627093-96-3Relevant articles and documents
Process method for producing dehydroacetic acid and patchoulenone and analogues thereof by utilizing carbon dioxide
-
Paragraph 0019; 0024, (2019/08/01)
The invention discloses a process method for producing dehydroacetic acid and patchoulenone and analogues thereof by utilizing carbon dioxide. The process method comprises the following steps: weighing a 4-hydroxy-2-pyrone substrate, a cuprous salt and cesium carbonate to be added into a Schleck bottle, degassing, and continuously introducing carbon dioxide; adding a solvent, reacting in an oil bath, and performing after-treatment to obtain a compound 2; carrying out an esterification reaction among the obtained compound 2, (1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride), 2-methylaminopyridine and isopropanol, and performing column chromatography isolation to obtain a compound 3; adding the compound 3 into anhydrous tetrahydrofuran containing sodium hydride, dropping methyl magnesium bromide (or isopentyl magnesium bromide) into the solution, reacting at a normal temperature, and separating, thereby obtaining the dehydroacetic acid or analogue compounds 4 thereof (or patchoulenone and analogue compounds 5 thereof). According to the process method disclosed by the invention, the raw material source is wide, the toxicity is low, and the price is low; the preparation process is simple, the equipment requirement is low, and industrial scale-up production is easily realized.
USE OF PYRONE CARBOXYLATES FOR CONTROLLING PESTS
-
Page 19, (2008/06/13)
Pests can be controlled by applying an effective amount of a compound of formula (1):wherein R is C2-C6 alkyl, C3-C6 cycloalkyl, (C3-C6 cycloalkyl)C1-C2 alkyl, 3,3,3-trifluoropropyl or 3,3,3-trifluoro-2-methylpropyl to pests or habitats of pests.
