62716-49-8 Usage
Uses
Used in Research Applications:
Decanoic-2,2-d2 Acid is used as an internal standard for the quantification of decanoic acid by gas chromatography (GC) or liquid chromatography-mass spectrometry (LC-MS) techniques. This application is crucial for accurate measurement and analysis of decanoic acid in various research settings.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, decanoic-2,2-d2 Acid serves as a valuable compound for studying the effects of decanoic acid on AMPA receptors. Its ability to selectively reduce glutamate-induced currents in specific AMPA receptor subtypes makes it a potential candidate for the development of drugs targeting neurological disorders.
Used in Neurological Research:
Decanoic-2,2-d2 Acid is used in neurological research to investigate the inhibition of epileptiform activity induced by pentylenetetrazole or low magnesium in rat hippocampal slices. This application aids in understanding the underlying mechanisms of epilepsy and the potential therapeutic effects of decanoic acid.
Used in Gastrointestinal Research:
In gastrointestinal research, decanoic-2,2-d2 Acid is utilized to study the effects of decanoic acid on isolated guinea pig duodenum, where it induces contractions. This application helps researchers understand the role of decanoic acid in gastrointestinal motility and its potential implications for treating gastrointestinal disorders.
Used in Analgesic Research:
Decanoic-2,2-d2 Acid is used in analgesic research to explore the pain-relieving properties of decanoic acid. Its ability to increase the escape threshold in an orofacial mechanical stimulation test in rats indicates potential applications in the development of novel analgesic drugs.
Used in Oncology Research:
In oncology research, decanoic-2,2-d2 Acid is employed to study the differences in plasma levels of decanoic acid in patients with colorectal cancer compared to those with breast cancer, ulcerative colitis, or without cancer. This information can provide insights into the role of decanoic acid in cancer progression and its potential as a biomarker or therapeutic target.
Check Digit Verification of cas no
The CAS Registry Mumber 62716-49-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,2,7,1 and 6 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 62716-49:
(7*6)+(6*2)+(5*7)+(4*1)+(3*6)+(2*4)+(1*9)=128
128 % 10 = 8
So 62716-49-8 is a valid CAS Registry Number.
62716-49-8Relevant articles and documents
Vibrational Study of the Dynamics of n-Decylammonium Chains in the Perovskite-Type Layer Compound (C10H21NH3)2CdCl4
Ricard, L.,Rey-Lafon, M.,Biran, C.
, p. 5614 - 5620 (1984)
The perovskite-type compound (C10H21NH3)2CdCl4(C10Cd) exhibits two phase transitions, at 35 and 39 deg C, connected with reorientations of the whole deacylammonium chains and melting of the hydrocarbon parts.A temperature-dependence study of the infrared and Raman spectra of C10Cd and three selectively deuterated derivatives, C10Cd-1,1-d2, C10Cd-2,2-d2, and C10Cd-4,4-d2, provides evidence for coupling between the two types of chain dynamics and allows for a more precise description of the conformational disorder of deacylammonium cations in the high-temperature phases.
Unexpected stereoselective exchange of straight-chain fatty acyl-CoA α-protons by human α-methylacyl-CoA racemase 1A (P504S)
Sattar, Fouzia A.,Darley, Daniel J.,Politano, Francesco,Woodman, Timothy J.,Threadgill, Michael D.,Lloyd, Matthew D.
supporting information; experimental part, p. 3348 - 3350 (2010/08/06)
α-Methylacyl-CoA racemase (AMACR; P504S) catalysed exchange of straight-chain fatty acyl-CoA α-protons. One α-proton was removed in each catalytic cycle, with the pro-S proton preferred. This reaction was most efficient for straight-chain substrates with longer side-chains. 2-Methyldecanoyl-CoA underwent α-proton exchange 3× more efficiently (as judged by Kcat/Km) than decanoyl-CoA.
