- Synthesis of C-Unsubstituted 1,2-Diazetidines and Their Ring-Opening Reactions via Selective N-N Bond Cleavage
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C-Unsubstituted 1,2-diazetidines, a rarely studied type of four-membered heterocyclic compounds, were synthesized through an operationally simple intermolecular vicinal disubstitution reaction. 1,2-Diazetidine derivatives bearing various N-arylsulfonyl groups were readily accessed and studied by experimental and computed Raman spectra. The ring-opening reaction of the diazetidine was explored and resulted in the identification of a selective N-N bond cleavage with thiols as nucleophiles, which stereoselectively produced a new class of N-sulfenylimine derivatives with C-aminomethyl groups.
- Chaminda Lakmal, Hetti Handi,Xu, Joanna Xiuzhu,Xu, Xue,Ahmed, Bassem,Fong, Christopher,Szalda, David J.,Ramig, Keith,Sygula, Andrzej,Webster, Charles Edwin,Zhang, Dongmao,Cui, Xin
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p. 9497 - 9503
(2018/06/22)
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- SYNTHESIS OF 10 - 13 MEMBERED TETRAAZACYCLOALKANES WITH A N,N'-BIS(2-AMINOETHYL)-HYDRAZINE UNIT IN THE RING
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A convenient method of synthesis of four new 10 -13 membered heteromacrocyclic systems with a N,N'-bis(2-aminoethyl)-hydrazine unit in the ring has been elaborated.This method consists in the cyclocondensation of the 1,2-diacylhydrazine alkali metal salts
- Goss, Ewa,Grudzinski, Stefan
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p. 305 - 312
(2007/10/02)
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