6272-36-2Relevant academic research and scientific papers
Synthesis of C-Unsubstituted 1,2-Diazetidines and Their Ring-Opening Reactions via Selective N-N Bond Cleavage
Chaminda Lakmal, Hetti Handi,Xu, Joanna Xiuzhu,Xu, Xue,Ahmed, Bassem,Fong, Christopher,Szalda, David J.,Ramig, Keith,Sygula, Andrzej,Webster, Charles Edwin,Zhang, Dongmao,Cui, Xin
, p. 9497 - 9503 (2018/06/22)
C-Unsubstituted 1,2-diazetidines, a rarely studied type of four-membered heterocyclic compounds, were synthesized through an operationally simple intermolecular vicinal disubstitution reaction. 1,2-Diazetidine derivatives bearing various N-arylsulfonyl groups were readily accessed and studied by experimental and computed Raman spectra. The ring-opening reaction of the diazetidine was explored and resulted in the identification of a selective N-N bond cleavage with thiols as nucleophiles, which stereoselectively produced a new class of N-sulfenylimine derivatives with C-aminomethyl groups.
SYNTHESIS OF 10 - 13 MEMBERED TETRAAZACYCLOALKANES WITH A N,N'-BIS(2-AMINOETHYL)-HYDRAZINE UNIT IN THE RING
Goss, Ewa,Grudzinski, Stefan
, p. 305 - 312 (2007/10/02)
A convenient method of synthesis of four new 10 -13 membered heteromacrocyclic systems with a N,N'-bis(2-aminoethyl)-hydrazine unit in the ring has been elaborated.This method consists in the cyclocondensation of the 1,2-diacylhydrazine alkali metal salts
