cas 6274-28-8, 3-AMINO-4-METHYLBENZENESULFONAMIDE | Articles data ｜lookchem

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6274-28-8

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SEVEN-MEMBERED RING COMPOUND, PRODUCTION METHOD THEREOF AND PHARMACEUTICAL USE THEREOF
A 7-membered heterocyclic compound having the formula (I), or its salt, or a solvate thereof with a chymase inhibitory action and useful for the prevention or treatment of various diseases, in which chymase is involved: a method for producing the same, and a pharmaceutical composition useful for the prevention or treatment of diseases, in which chymase is involved, including the compound of having the formula (I), or its pharmaceutically acceptable salt, or a solvate thereof are provided.
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Page/Page column 50

(2009/03/07)

7-MEMBERED RING COMPOUND, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL USE THEREOF
A 7-membered heterocyclic compound having the formula (I), or its salt, or a solvate thereof with a chymase inhibitory action and useful for the prevention or treatment of various diseases, in which chymase is involved: a method for producing the same, and a pharmaceutical composition useful for the prevention or treatment of diseases, in which chymase is involved, including the compound of having the formula (I), or its pharmaceutically acceptable salt, or a solvate thereof are provided.
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Page/Page column 41

(2008/06/13)

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Chemical Properties

Melting Point: 176 °C
Boiling Point: 411.2 °C at 760 mmHg
Flash Point:202.5 °C
Density: 1.359 g/cm³
Storage Temp.:Keep in dark place,Sealed in dry,Room Temperature
Vapor Pressure: 5.7E-07mmHg at 25°C
Refractive Index: 1.609
PKA: 10.46±0.60(Predicted)
PSA: 94.56000
LogP: 2.58690

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