627511-06-2

Basic information

• Product Name: 2-FURAN-3-YL-1H-PYRROLO[2,3-C]PYRIDINE
• Synonyms: 2-FURAN-3-YL-1H-PYRROLO[2,3-C]PYRIDINE
• CAS NO: 627511-06-2
• Molecular Formula: C11H8N2O
• Molecular Weight: 184.19
• Mol File: 627511-06-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-FURAN-3-YL-1H-PYRROLO[2,3-C]PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-FURAN-3-YL-1H-PYRROLO[2,3-C]PYRIDINE(627511-06-2)
• EPA Substance Registry System: 2-FURAN-3-YL-1H-PYRROLO[2,3-C]PYRIDINE(627511-06-2)

Safety Data

• Hazardous Substances Data: 627511-06-2(Hazardous Substances Data)

Upstream product

• 3430-27-1 3-amino-4-methylpyridine 
• 614-98-2 ethyl 3-furancarboxylate 
• 627510-97-8 N-{4-[(E)-2-(3-furyl)ethenyl]pyridin-3-yl}hydroxylamine 
• 627510-91-2 4-[(E)-2-(3-furyl)ethenyl]-3-nitropyridine 
• 5832-44-0 3-nitro-4-methylpyridine 
• 498-60-2 furan-3-carboxaldehyde 
• 627511-03-9 2-(3-furyl)-1H-pyrrolo[2,3-c]pyridin-1-ol 

Relevant articles and documents

A novel one-step synthesis of 2-substituted 6-azaindoles from 3-amino-4-picoline and carboxylic esters

Dilithiation of 3-amino-4-picoline (1) was achieved with sec-BuLi at room temperature. Condensation of the resulting dianion (2) with carboxylic esters afforded a wide range of 2-substituted 6-azaindoles in good yields.

Synthesis of 2-aryl-1-hydroxyazaindoles and 2-arylazaindoles via oxidation of o-hydroxyaminostyrylpyridines

2-Aryl-1-hydroxyazaindoles (pyrrolopyridin-1-ols) are prepared via an oxidation/cyclization of o-hydroxyaminostyrylpyridines with DDQ. Reduction of the N-OH bond affords the corresponding 2-arylazaindoles (1H-pyrrolopyridines). The scope of the cyclization is explored via (i) the condensation of 4-methyl-3-nitropyridine with various aryl aldehydes to afford 2-aryl substituted 6-azaindoles and, (ii) the synthesis of 2-phenyl-4-, 5- and 7-azaindoles.