63769-98-2

Basic information

• Product Name: BOC-ALA-ALA-PRO-OH
• Synonyms: BOC-ALA-ALA-PRO-OH;Boc-AAP-OH
• CAS NO: 63769-98-2
• Molecular Formula: C₁₆H₂₇N₃O₆
• Molecular Weight: 357.4
• Mol File: 63769-98-2.mol

Chemical Properties

• Boiling Point: 626.2±55.0 °C(Predicted)
• Appearance: /
• Density: 1.228±0.06 g/cm3(Predicted)
• Storage Temp.: -15°C
• PKA: 3.44±0.20(Predicted)
• CAS DataBase Reference: BOC-ALA-ALA-PRO-OH(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-ALA-ALA-PRO-OH(63769-98-2)
• EPA Substance Registry System: BOC-ALA-ALA-PRO-OH(63769-98-2)

Safety Data

• Hazardous Substances Data: 63769-98-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
BOC-ALA-ALA-PRO-OH is used as a key building block for the synthesis of peptides and proteins. Its role in this industry is crucial for the development of new drugs and therapeutic agents, as it allows for the controlled assembly of complex peptide structures.
Used in Agrochemical Industry:
In the agrochemical sector, BOC-ALA-ALA-PRO-OH is utilized as a component in the synthesis of bioactive peptides. These peptides can have applications in pest control, plant protection, and other agricultural areas, contributing to more effective and targeted agrochemical products.
Used in Materials Science:
BOC-ALA-ALA-PRO-OH is employed in materials science for the development of advanced materials with specific properties. The controlled synthesis of peptides using this compound can lead to the creation of biomaterials, sensors, and other innovative materials with applications in various fields.

Upstream product

• 50903-48-5 N-tert.butyloxycarbonyl-alanine pentafluorophenyl ester 
• 13485-59-1 L-alanyl-L-proline 
• 108827-49-2 H-Pro-OTmse 
• 21027-01-0 N-benzyloxycarbonyl-L-alanyl-L-proline 
• 63769-97-1 Boc-Ala-Ala-Pro-O-Bzl 

Downstream Products

• 90105-47-8 (S)-1-[(S)-2-((S)-2-Amino-propionylamino)-propionyl]-pyrrolidine-2-carboxylic acid ((S)-3-chloro-1-isopropyl-2-oxo-propyl)-amide 
• 65144-33-4 N-3-carboxypropanoyl-alanyl-alanyl-prolyl-valyl-chloromethylketone 
• 1001200-95-8 C₇₀H₈₂N₁₀O₁₅ 
• 1140971-98-7 Boc-AAPF-CH₂Cl 
• 1336878-84-2 C₅₀H₅₅N₇O₁₁ 
• 1140971-99-8 H-AAPF-CH₂Cl*HCl 
• 106771-22-6 N-<<5-(dimethylamino)-1-naphtalenyl>sulfonyl>-L-alanyl-L-alanyl-N-<3,3,3-trifluoro-1-(1-methylethyl)-2-oxopropyl>-L-prolinamide 

Relevant articles and documents

Design of a novel secondary structure scaffolding device: Induction of a reverse turn in tetrapeptides by incorporating a β-amino acid and stereocontrolled free radical α-substitution reactions in peptide motifs

The incorporation of α-substituted β-amino acids into a tetrapeptide motif induces a reverse rum in aprotic solvent systems as revealed by NOESY and ROESY techniques, and by CD spectra. The conformations of these compounds have been studied by molecular modeling, and further supported by performing a highly stereoselective free radical allylation reaction on an α-phenylseleno β-amino acid unit within the tetrapeptide.

Peptidase inhibitors

This invention relates to analogs of peptidase substrates in which the amide group containing the scissile amide bond of the substrate peptide has been replaced by an activated electrophilic ketone moiety. These analogs of the peptidase substrates provide specific enzyme inhibitors for a variety of proteases, the inhibition of which will have useful physiological consequences in a variety of disease states.