638218-70-9

Basic information

• Product Name: 3-benzofurancarboxylic acid, 6-hydroxy-2-Methyl-, Methyl ester
• Synonyms: 3-benzofurancarboxylic acid, 6-hydroxy-2-Methyl-, Methyl ester;Methyl 6-hydroxy-2-methylbenzofuran-3-carboxylate
• CAS NO: 638218-70-9
• Molecular Formula: C₁₁H₁₀O₄
• Molecular Weight: 206.1947
• Mol File: 638218-70-9.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-benzofurancarboxylic acid, 6-hydroxy-2-Methyl-, Methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-benzofurancarboxylic acid, 6-hydroxy-2-Methyl-, Methyl ester(638218-70-9)
• EPA Substance Registry System: 3-benzofurancarboxylic acid, 6-hydroxy-2-Methyl-, Methyl ester(638218-70-9)

Safety Data

• Hazardous Substances Data: 638218-70-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Applications:
Esculetin is used as a therapeutic agent for its anti-inflammatory, antioxidant, and anticancer properties. It has been investigated for its potential to modulate various biological pathways and exert inhibitory effects on tumor growth and progression.
Used in Cosmetic and Skincare Industry:
Esculetin is used as an active ingredient in cosmetic and skincare products for its potential skin lightening and anti-aging effects. It may contribute to improving skin appearance and reducing signs of aging.
Used in Research and Development:
Esculetin is utilized in research and development for its potential health benefits and applications in various industries. Further studies are needed to explore its mechanisms of action, efficacy, and safety profile in different therapeutic areas.

Upstream product

• 92810-82-7 6-acetoxy-2-methylbenzofuran 
• 108-46-3 recorcinol 
• 67-56-1 methanol 
• 1316841-72-1 acetic acid 4-acetyl-3,4-dihydrocoumarin-7-yl ester 
• 95239-02-4 C₁₀H₁₆N₂O₄ 

Downstream Products

• 638218-93-6 methyl 2-methyl-6-[thieno[3,2-b]pyridin-7-yloxy]benzofuran-3-carboxylate 

Relevant articles and documents

Novel and convenient synthesis of benzofurans from dihydrocoumarins

7-Hydroxy-3,4-dihydrocoumarin-4-carboxylic acid (7), conveniently prepared from m-resorcinol and maleic anhydride, was surprisingly transformed by acid anhydride and pyridine into the corresponding ketone, 4-alkanoyl analog 11. The latter reacted in turn

Metal and oxidant-free Br?nsted acid-mediated cascade reaction to substituted benzofurans

Substituted hydroxy-benzofurans are easily accessible by treatment of resorcinols and 1,2-diaza-1,3-dienes (DDs) under acidic conditions. The reaction happens through an uncommon Michael reaction between aromatic derivatives as aromatic C(sp2)-

Benzofused heterozryl amide derivatives of thienopyridines useful as therapeutic agents, pharmaceutical compositions including the same, and methods for their use

The invention relates to compounds represented by the formula I and to prodrugs or metabolites thereof, or pharmaceutically acceptable salts or solvates of said compounds, said prodrugs, and said metabolites, wherein Z, Y, R11 and R14, R15, R16, and R17 are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula I and to methods of treating hyperproliferative disorders in a mammal by administering the compounds of formula I.

BENZOFUSED HETEROARYL AMIDE DERIVATIVES OF THIENOPYRIDINES USEFUL AS THERAPEUTIC AGENTS, PHARMACEUTICAL COMPOSITIONS INCLUDING THE SAME, AND METHODS FOR THEIR USE

The invention relates to compounds represented by the formula I and to prodrugs or metabolites thereof, or pharmaceutically acceptable salts or solvates of said compounds, said prodrugs, and said metabolites, wherein Z, Y, R11 and R14, R15, R16, and R17 are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula I and to methods of treating hyperproliferative disorders in a mammal by administering the compounds of formula I.