Synthesis and Platelet Aggregation Inhibiting Activity of Prostaglandin D Analogues
Several prostaglandin D (PGD) analogues have been synthesized, incorpotating the following variations: (a) varying degrees of side-chain unsaturation, (b) C-9 hydroxy removed or in the unnatural 9β configuration, (c) metabolically stabilized analogues (e.
Bundy, Gordon L.,Morton, D. R.,Peterson, D. C.,Nishizawa, E. E.,Miller, W. L.
p. 790 - 799
(2007/10/02)
9-Deoxy-PGF2 Analogs
Prostaglandin analogs with the following cyclopentane ring structure: STR1 are disclosed along with intermediates useful in their preparation and processes for their preparation. These analogs are useful for some of the same pharmacological purposes as the prostaglandins.
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(2008/06/13)
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