641571-03-1

Basic information

• Product Name: N-BOC-3-BROMO-5-TRIFLUOROMETHYLANILINE
• Synonyms: N-BOC-3-BROMO-5-TRIFLUOROMETHYLANILINE;t-Butyl 3-bromo-5-(trifluoromethyl)phenylcarbamate
• CAS NO: 641571-03-1
• Molecular Formula: C₁₂H₁₃BrF₃NO₂
• Molecular Weight: 340.15
• Mol File: 641571-03-1.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: N-BOC-3-BROMO-5-TRIFLUOROMETHYLANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-BOC-3-BROMO-5-TRIFLUOROMETHYLANILINE(641571-03-1)
• EPA Substance Registry System: N-BOC-3-BROMO-5-TRIFLUOROMETHYLANILINE(641571-03-1)

Safety Data

• Hazardous Substances Data: 641571-03-1(Hazardous Substances Data)

Usage

Uses

Since the provided materials do not specify the uses of N-BOC-3-BROMO-5-TRIFLUOROMETHYLANILINE, I can only infer potential applications based on its classification as an anilide and its chemical properties. Here are some hypothetical uses:
Used in Pharmaceutical Industry:
N-BOC-3-BROMO-5-TRIFLUOROMETHYLANILINE is used as an intermediate in the synthesis of pharmaceutical compounds for its ability to be modified and incorporated into various drug molecules.
Used in Chemical Synthesis:
N-BOC-3-BROMO-5-TRIFLUOROMETHYLANILINE is used as a reagent or building block in the synthesis of complex organic molecules, taking advantage of its unique functional groups and properties.
Used in Research and Development:
N-BOC-3-BROMO-5-TRIFLUOROMETHYLANILINE is used as a research compound to study its chemical behavior and explore its potential in new applications, such as material science or as a precursor to new types of compounds.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 54962-75-3 [3-bromo-5-(trifluoromethyl)phenyl]amine 

Downstream Products

• 1207351-03-8 5-trifluoromethyl-3-(tert-butyl-oxycarbonyl)amino-phenylboronic acid 
• 1072710-87-2 3-(3-methyl-3H-imidazol-4-yl)-5-trifluoromethyl-phenylamine 
• 1072710-96-3 [3-(3-methyl-3H-imidazol-4-yl)-5-trifluoromethyl-phenyl]-carbamic acid tert-butyl ester 
• 641571-21-3 3-(4-methyl-1-piperazinyl)-5-(trifluoromethyl)benzenamine 

Relevant articles and documents

DIARYL UREA DERIVATIVES IN THE TREATMENT OF PROTEIN KINASE DEPENDENT DISEASES

The invention relates to the use of diaryl urea derivatives for the manufacture of pharmaceutical compositions for the treatment of RET dependent disorders, especially RET dependent tumor diseases. The invention further relates to novel N-[4-(pyrimidin-4-yloxy)-phenyl]-N’-phenyl-urea derivatives and their use in the treatment of the animal or human body, especially in the treatment of a protein kinase dependent disease, to pharmaceutical compositions comprising such novel N-[4-pyrimidin-4-yloxy)-phenyl]-N’-phenyl-urea derivatives and to the use of such novel N-[4-(pyrimidin-4-yloxy)-phenyl]-N’-phenyl-urea derivatives for the preparation of pharmaceutical compositions for use in the treatment of protein kinase dependent diseases, especially of proliferative diseases, such as tumour diseases.

INHIBITORS OF TYROSINE KINASES

The invention relates to compounds of formula (I) Wherein the substituents R1, R2 and R4 have the meaning as set forth and explained in the description of the invention, to processes for the preparation of these compounds, pharmaceutical compositions containing same, the use thereof optionally in combination with one or more other pharmaceutically active compounds for the therapy of a disease which responds to an inhibition of protein kinase activity, especially a neoplastic disease, in particular leukaemia, and a method for the treatment of such disease.