643083-82-3Relevant articles and documents
NPC1L1 (NPC3) and methods of identifying ligands thereof
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, (2011/04/14)
The present invention provides human, rat and mouse NPCIL1 polypeptides and polynucleotides encoding the polypeptides. Methods for detecting ligands which bind to NPC1L1 and block intestinal cholesterol absorption are provided. Also included is a method o
Synthesis of trisubstituted pyrroles from rhodium-catalyzed alkyne head-to-tail dimerization and subsequent goldcatalyzed cyclization
Peng, Hong Mei,Zhao, Jing,Li, Xingwei
supporting information; experimental part, p. 1371 - 1377 (2009/12/07)
Dimerization of N-protected propargylic amines in a rather rare head-to-tail mode has been achieved under mild conditions with high selectivity using rhodium catalysts. The JV-protecting group could be a sulfonyl, carbamate, or carbonyl functionality and
Anti-hypercholesterolemic compounds
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Page/Page column 12-13, (2008/06/13)
This invention provides cholesterol absorption inhibitors of Formula I: and the pharmaceutically acceptable salts and esters thereof. The compounds are useful for lowering plasma cholesterol levels, particularly LDL cholesterol, and for treating and preventing atherosclerosis and atherosclerotic disease events.
ANTI-HYPERCHOLESTEROLEMIC COMPOUNDS
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Page/Page column 25, (2008/06/13)
This invention provides cholesterol absorption inhibitors of Formula (I), and the pharmaceutically acceptable salts and esters thereof. The compounds are useful for lowering plasma cholesterol levels, particularly LDL cholesterol, and for treating and preventing atherosclerosis and atherosclerotic disease events.
Anti-hypercholesterolemic compounds
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Page/Page column 9; 10, (2008/06/13)
This invention provides cholesterol absorption inhibitors of Formula I: and the pharmaceutically acceptable salts and esters thereof. The compounds are useful for lowering plasma cholesterol levels, particularly LDL cholesterol, and for treating and preve