Process for preparing thiophene derivatives and thiophene derivatives obtained thereby
Process for the preparation of a series of thiophene derivatives, from which 2-thiopheneacetic acid derivatives can easily be prepared, in high yields and selectivity by using substituted or unsubstituted thiophenes as the starting materials by easy operations. 2-Thiopheneacetic acid derivatives are very useful compounds as the chemical modifier of penicillin and cephalosporin. Novel compounds, i.e. α-arylthio-2-thiopheneacetic acids are also disclosed. These compounds are useful as the intermediates of the synthesis of 2-thiopheneacetic acids.
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(2008/06/13)
Aromatic acetic acid derivatives having sulfur atom at alpha-position and process for their preparation
Aromatic acetic acid derivatives having a sulfur atom at the alpha-position, and a process for their preparation. Useful drugs can be produced from these derivatives.
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(2008/06/13)
Cephalosporins having a sulfur containing functional group in the 7-position side chain
Cephalosporins having a sulfur-containing functional group of the formula STR1 present at the carbon atom directly bonded to the thienyl or furyl group in the side chain of the 7-position of cephem derivatives. These compounds are useful as anti-bacterial agents against Gram-positive and Gram-negative bacteria.
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(2008/06/13)
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