651310-29-1

Basic information

• Product Name: 3-(4-(methylsulfonyl)phenyl)propan-1-ol
• Synonyms: 3-(4-(methylsulfonyl)phenyl)propan-1-ol;4-(methylsulfonyl)benzenepropanol
• CAS NO: 651310-29-1
• Molecular Formula: C₁₀H₁₄O₃S
• Molecular Weight: 214.28136
• Mol File: 651310-29-1.mol

Chemical Properties

• Boiling Point: 410.1±37.0 °C(Predicted)
• Appearance: /
• Density: 1.203±0.06 g/cm3(Predicted)
• PKA: 14.97±0.10(Predicted)
• CAS DataBase Reference: 3-(4-(methylsulfonyl)phenyl)propan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-(methylsulfonyl)phenyl)propan-1-ol(651310-29-1)
• EPA Substance Registry System: 3-(4-(methylsulfonyl)phenyl)propan-1-ol(651310-29-1)

Safety Data

• Hazardous Substances Data: 651310-29-1(Hazardous Substances Data)

Usage

Class of compound

Secondary alcohols

Structural relation

Related to phenylpropanolamine

Structure

Phenyl ring with sulfonylmethyl group at para position, attached to propan-1-ol moiety

Functional group

Sulfonyl group attached to methyl group

Potential use

Pharmaceutical agent or chemical intermediate

Upstream product

• 105135-96-4 3-(4-(methylsulfonyl)phenyl)prop-2-yn-1-ol 
• 387350-46-1 3-[4-(methylsulfonyl)phenyl]propanoic acid 
• 59209-70-0 4-(methylthio)benzenepropanol 
• 138485-81-1 3-(4-(methylmercapto)phenyl)propionic acid 

Relevant articles and documents

NOVEL IMIDAZOLE COMPOUND AND USE THEREOF AS MELANOCORTIN RECEPTOR AGONIST

The present invention relates to a novel imidazole compound or a pharmaceutically acceptable salt thereof having a melanocortin receptor agonistic activity, and medical use thereof. The present invention relates to an imidazole compound represented by general formula [I] [wherein: Ring A represents an optionally substituted aryl group or the like; R1 represents a hydrogen atom, an optionally substituted alkyl group, or the like; R2 represents a hydrogen atom, a halogen atom, or the like; and R3 represents an optionally substituted alkyl group] or a pharmaceutically acceptable salt thereof.

Pharmaceutical compositions (by machine translation)

[Problem] imidazole compound or its pharmacologically acceptable salt in the melanocortin receptor activity that operates as an active ingredient of a pharmaceutical composition comprising. "I" general formula [a]" Formula, the aryl group may be substituted A ring represents a; R1 Represents a hydrogen atom, or an alkyl group which may be substituted represented; R2 Represents a hydrogen atom, a halogen atom or represents a; R3 The alkyl group may be substituted " represented by the imidazole compound, its pharmacologically acceptable salt as an active ingredient in a pharmaceutical composition. [Drawing] no (by machine translation)

Optimization of asymmetric oxidation of sulfides with the Fe(salan) complex in water and the expanded scope of its application

The scope of asymmetric oxidation of sulfides using Fe(salan) complex as a catalyst and aqueous hydrogen peroxide as an oxidant in water was broadened by optimizing the reaction conditions with respect to reaction temperature, catalyst loading, and amount of water solvent. The oxidation proceeded with high enantioselectivity under the optimized conditions. The undesired over-oxidation of the resultant sulfoxides was significantly suppressed and the yields of sulfoxides were improved. Various functional groups were tolerant of the conditions.

PHENETANOLAMINE DERIVATIVES

Compounds of formula (I) and salts, solvates, and physiologically functional derivatives thereof, useful for the prophylaxis or treatment of a clinical condition for which a selective β2-adrenoreceptor agonist is indicated, for example asthma or chronic o

5-Substituted isoquinoline derivatives

A compound represented by the following formula (1) or a salt thereof: wherein R1 represents hydrogen atom, a halogen atom and the like; R2 represents hydrogen atom, a halogen atom, a C1-6 alkyl group and the like; and R3 represents —O—X—C(A1)(A11)—C(A2)(A2l)—N(A3l)(A3)(X represents propylene group etc., A11 and A21 represent hydrogen atom, or a C1-6 alkyl group, A31 represents a C1-6 alkyl group substituted with hydroxyl group, or hydrogen atom, and A1, A2, and A3 represent hydrogen atom, a C1-6 alkyl group and the like) and the like, which has an inhibitory activity on the phosphorylation of myosin regulatory light chain, and is useful for treatment of diseases relating to contraction of various cells and the like.