655233-39-9

Basic information

• Product Name: (6R,7R)-7-AMINO-8-OXO-3-((2S)-TETRAHYDROFURAN-2-YL)-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC ACID 4-NITROBENZYL ESTER HCL
• Synonyms: (6R,7R)-7-AMINO-8-OXO-3-((2S)-TETRAHYDROFURAN-2-YL)-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC ACID 4-NITROBENZYL ESTER HCL
• CAS NO: 655233-39-9
• Molecular Formula: C18H20ClN3O6S
• Molecular Weight: 441.8859
• Mol File: 655233-39-9.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (6R,7R)-7-AMINO-8-OXO-3-((2S)-TETRAHYDROFURAN-2-YL)-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC ACID 4-NITROBENZYL ESTER HCL(CAS DataBase Reference)
• NIST Chemistry Reference: (6R,7R)-7-AMINO-8-OXO-3-((2S)-TETRAHYDROFURAN-2-YL)-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC ACID 4-NITROBENZYL ESTER HCL(655233-39-9)
• EPA Substance Registry System: (6R,7R)-7-AMINO-8-OXO-3-((2S)-TETRAHYDROFURAN-2-YL)-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC ACID 4-NITROBENZYL ESTER HCL(655233-39-9)

Safety Data

• Hazardous Substances Data: 655233-39-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(6R,7R)-7-AMINO-8-OXO-3-((2S)-TETRAHYDROFURAN-2-YL)-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC ACID 4-NITROBENZYL ESTER HCL is used as a pharmaceutical compound for its potential therapeutic applications. (6R,7R)-7-AMINO-8-OXO-3-((2S)-TETRAHYDROFURAN-2-YL)-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC ACID 4-NITROBENZYL ESTER HCL's unique structure and chemical properties allow it to interact with biological targets, making it a candidate for the development of new drugs to treat various diseases.
Used in Drug Synthesis:
In the field of drug synthesis, (6R,7R)-7-AMINO-8-OXO-3-((2S)-TETRAHYDROFURAN-2-YL)-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC ACID 4-NITROBENZYL ESTER HCL serves as a key intermediate or building block in the synthesis of more complex pharmaceutical agents. Its versatile functional groups enable further chemical modifications to optimize the drug's efficacy, selectivity, and pharmacokinetic properties.
Used in Medicinal Chemistry Research:
(6R,7R)-7-AMINO-8-OXO-3-((2S)-TETRAHYDROFURAN-2-YL)-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC ACID 4-NITROBENZYL ESTER HCL is utilized in medicinal chemistry research to explore its binding affinity, selectivity, and mechanism of action against various biological targets. Understanding the compound's interactions with these targets can provide valuable insights into the design of more effective and selective drugs.

Upstream product

• 436100-74-2 (3R,4R)-(4-nitrophenyl)methyl ester α-hydroxy-2-oxo-4-[[2-oxo-2-[(1S)-(tetrahydro-2-furanyl)]ethyl]thio]-3-[(phenylacetyl)amino]-1-azetidineacetic acid 

Relevant articles and documents

Development of an alternative process for the manufacture of a key starting material for cefovecin sodium

A process has been developed for the use of trimethylphosphite for the formation of the six-membered 3,6-dihydro-2H-[1,3]-thiazine ring in the cephem architecture by an intramolecular Horner-Emmons-Wadsworth condensation. The process is a suitable alternative to the traditional Wittig process, which uses trimethylphosphine. The process developed is a highly telescoped reaction pathway consisting of at least six known reaction intermediates that was scaled for production use to produce 2.

PROCESS FOR PREPARING CEPHALOSPORIN INTERMEDIATES USING α-IODO-1-AZETIDINEACETIC ACID ESTERS AND TRIALKYLPHOSPHITES

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