65990-86-5

Basic information

• Product Name: 2,2,2-TRIFLUORO-1-(4-CHLORO-PHENYL)-ETHYLAMINE HYDROCHLORIDE
• Synonyms: 2,2,2-TRIFLUORO-1-(4-CHLORO-PHENYL)-ETHYLAMINE HYDROCHLORIDE;1-(4-chlorophenyl)-2,2,2-trifluoroethan-1-aMine hydrochloride;BenzeneMethanaMine, 4-chloro-a-(trifluoroMethyl)-, hydrochloride;1-(4-CHLOROPHENYL)-2,2,2-TRIFLUOROETHANAMINE HYDROCHLORIDE;1-(4-Chlorophenyl)-2,2,2-trifluoroethanamine-HCl;4-Chloro-alpha-(trifluoromethyl)benzenemethanamine hydrochloride
• CAS NO: 65990-86-5
• Molecular Formula: C₈H₇ClF₃N*ClH
• Molecular Weight: 246.058
• Mol File: 65990-86-5.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,2,2-TRIFLUORO-1-(4-CHLORO-PHENYL)-ETHYLAMINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2,2-TRIFLUORO-1-(4-CHLORO-PHENYL)-ETHYLAMINE HYDROCHLORIDE(65990-86-5)
• EPA Substance Registry System: 2,2,2-TRIFLUORO-1-(4-CHLORO-PHENYL)-ETHYLAMINE HYDROCHLORIDE(65990-86-5)

Safety Data

• Hazardous Substances Data: 65990-86-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2,2,2-TRIFLUORO-1-(4-CHLORO-PHENYL)-ETHYLAMINE HYDROCHLORIDE is used as an intermediate in the synthesis of various pharmaceuticals. Its unique structure allows it to be a key component in the development of new drugs, contributing to the advancement of medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, 2,2,2-TRIFLUORO-1-(4-CHLORO-PHENYL)-ETHYLAMINE HYDROCHLORIDE serves as an intermediate for the production of agrochemicals. Its role in this industry is crucial for the synthesis of compounds that can protect crops and enhance agricultural productivity.
Used as a Building Block in Chemical Synthesis:
Beyond its applications in pharmaceuticals and agrochemicals, 2,2,2-TRIFLUORO-1-(4-CHLORO-PHENYL)-ETHYLAMINE HYDROCHLORIDE is also utilized as a building block in the preparation of other chemical compounds. Its versatility in chemical reactions makes it a valuable asset in the synthesis of a wide range of products across various industries.

InChI:InChI=1/C8H7ClF3N.ClH/c9-6-3-1-5(2-4-6)7(13)8(10,11)12;/h1-4,7H,13H2;1H

Upstream product

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Relevant articles and documents

Thermocontrolled benzylimine-benzaldimine rearrangement over Nafion-H catalysts for efficient entry into α-trifluoromethylbenzylamines

Nafion-H and Nafion SAC-13 are efficient solid Br?nsted acid catalysts for the preparation of trifluoromethyl ketimines from benzylamines and trifluoromethylated ketones in high yields. A finely tuned benzylimine- benzaldimine rearrangement by facile 1,3-hydrogen shift has been achieved for the formation of fluorinated benzaldimines in high yields by careful optimization of reaction conditions including attempts under microwave conditions and a flow system. These α-trifluoromethylated benzaldimines are efficient precursors for pharmaceutically important α- trifluoromethylated benzylamines, accessed through their direct acid hydrolysis.