65999-71-5Relevant articles and documents
Novel heteroarylcarboxamide derivative or pharmacutically acceptable salt thereof, process for the preparation thereof and pharmaceutical composition for prevention or treatment of RAGE receptor related diseases containing the same as an active ingredient
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Paragraph 0261; 0267-0268; 0281; 0285-0286, (2021/11/02)
The present invention refers to novel heterocyclic biting Carbox probably the id derivative acceptable salt, and manufacturing method thereof including RAGE associated active acetylcholinesterase receptor or pharmaceutical composition for preventing or treating disease is directed to. Heterocycle by the present invention a derivative biting Carbox probably the id RAGE receptor antagonism in by, nerve cells with the beta loss oh with wheat id RAGE conjunction with receptor, inhibiting moving into brain, the resulting beta Amyloid plaque formed 21 is known to effectively inhibit generation.. Furthermore, memory a chemicals that are important in the acetylcholine for decomposing an aromatic thus inhibiting acetylcholine s reel sacrifice , RAGE disease associated active acetylcholinesterase receptor or Alzheimer's disease, cerebrovascular dementia, dementia due to damage bean curd, multi blockade dementia, Alzheimer's disease or the like dementia alcoholic or mixed dementia multi blockade and including dementia, pick (pick) bottle, a smartcrew [...] -Jakob (Creutzfeldt-jakob) bottle, that thyroid gland symptoms , bean curd a blade Parkinson (Parkinson) bottle, Huntington's disease (Huntington) which is useful in preventing or treating, can be used.
1,3,3-Trimethyl-2-methylene indoline cationic n-methyl azo dyes
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, (2008/06/13)
New yellow cationic dyes of the formula STR1 ARE DISCLOSED WHEREIN X represents hydrogen or halogen, R represents an optionally substituted alkyl group or cycloalkyl group, Or --CH2 -- if this is linked with the phenylene group in the o-position with respect to the oxygen bond to form a 6-membered ring and n represents 1, R1 represents an unsubstituted, straight-chain or branched-chain alkyl group having 1 to 5 carbon atoms, R2 represents a substituted, or preferably unsubstituted, straight-chain or branched-chain alkyl group having 1 to 5 carbon atoms, N represents the numbers 1 or 2, and An represents an anion, which dyes are useful for dyeing and printing of textile material especially polyacrylonitrile.