- 2 - Alkynyl mannose derivative and application thereof
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The present invention relates to a 2-alkynyl mannose derivative and an application thereof. The mannose derivative, as well as a pharmaceutically acceptable salt, an isotope and an isomer thereof have the structure represented by general formula I. The de
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Paragraph 0082-0084
(2021/10/05)
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- HETEROARYLPHENOXY BENZAMIDE KAPPA OPIOID LIGANDS
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The present invention provides compounds of Formula I: and pharmaceutically acceptable salts thereof wherein the variables R1, R2, R3, R4, R9, X, m and n are as defined herein; processes for the prepa
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Paragraph 0283; 0284
(2018/06/09)
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- Two-stage sonogashira coupling method in the synthesis of auxin active acetylenes
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A sequential Sonogashira coupling of a protected acetylene precursor with aryl halides (5) followed by pyrazolyl iodides (14) allows efficient access to the unsymmetrical aryl-heteroarylacetylene (8). Subsequent regioselective lithiation exchange followed by dimethyl oxalate quench produced readily vicinal ketoesters (9) which show auxin effects in a wide variety of plant species.
- Wayne Craig,Eberle, Martin,Irminger, Bruno,Schueckenboehmer, Anegret,Laime, Yvette,Mueller, Patrick
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p. 1967 - 1974
(2008/09/16)
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