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3-Amino-4-iodobenzonitrile, a chemical compound with the molecular formula C7H5IN2, is a white to off-white crystalline solid. It serves as a versatile intermediate in the synthesis of pharmaceuticals, agrochemicals, dyes, pigments, and other specialty chemicals. Its multifunctional reactivity and broad application potential make it a valuable chemical in the field of organic chemistry.

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  • 665033-21-6 Structure
  • Basic information

    1. Product Name: 3-AMino-4-iodobenzonitrile
    2. Synonyms: 3-AMino-4-iodobenzonitrile
    3. CAS NO:665033-21-6
    4. Molecular Formula: C7H5IN2
    5. Molecular Weight: 244.03247
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 665033-21-6.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
    8. Solubility: N/A
    9. CAS DataBase Reference: 3-AMino-4-iodobenzonitrile(CAS DataBase Reference)
    10. NIST Chemistry Reference: 3-AMino-4-iodobenzonitrile(665033-21-6)
    11. EPA Substance Registry System: 3-AMino-4-iodobenzonitrile(665033-21-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 665033-21-6(Hazardous Substances Data)

665033-21-6 Usage

Uses

Used in Pharmaceutical Industry:
3-Amino-4-iodobenzonitrile is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 3-Amino-4-iodobenzonitrile is utilized as an intermediate in the production of agrochemicals, aiding in the creation of compounds that can enhance crop protection and yield.
Used in Dye and Pigment Production:
3-Amino-4-iodobenzonitrile is employed as a building block in the organic synthesis of dyes and pigments, contributing to the coloration and properties of these compounds for various applications.
Used in Specialty Chemicals:
As a versatile chemical, 3-Amino-4-iodobenzonitrile is used in the production of specialty chemicals, where its unique properties can be harnessed for specific industrial needs.
Used as a Reagent in Organic Synthesis:
3-Amino-4-iodobenzonitrile is used as a reagent in the preparation of various functionalized heterocycles and other organic compounds, facilitating the creation of complex molecules for research and industrial applications.

Check Digit Verification of cas no

The CAS Registry Mumber 665033-21-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,6,5,0,3 and 3 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 665033-21:
(8*6)+(7*6)+(6*5)+(5*0)+(4*3)+(3*3)+(2*2)+(1*1)=146
146 % 10 = 6
So 665033-21-6 is a valid CAS Registry Number.

665033-21-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-Amino-4-iodobenzonitrile

1.2 Other means of identification

Product number -
Other names CL9066

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:665033-21-6 SDS

665033-21-6Relevant articles and documents

Synthesis of benzannelated sultams by intramolecular Pd-catalyzed arylation of tertiary sulfonamides

Rassadin, Valentin A.,Scholz, Mirko,Klochkova, Anastasiia A.,De Meijere, Armin,Sokolov, Victor V.

supporting information, p. 1932 - 1939 (2017/09/27)

A new and efficient approach to five- and six-membered benzannelated sultams by intramolecular C-arylation of tertiary 1-(methoxycarbonyl)methanesulfonamides under palladium catalysis is described. In case of the α-toluenesulfonamide derivative, an unexpected formation of a 2,3-diarylindole was observed under the same conditions.

Non-steroidal dissociated glucocorticoid agonists: Indoles as A-ring mimetics and function-regulating pharmacophores

Betageri, Raj,Gilmore, Thomas,Kuzmich, Daniel,Kirrane, Thomas M.,Bentzien, J?rg,Wiedenmayer, Dieter,Bekkali, Younes,Regan, John,Berry, Angela,Latli, Bachir,Kukulka, Alison J.,Fadra, Tazmeen N.,Nelson, Richard M.,Goldrick, Susan,Zuvela-Jelaska, Ljiljana,Souza, Don,Pelletier, Josephine,Dinallo, Roger,Panzenbeck, Mark,Torcellini, Carol,Lee, Heewon,Pack, Edward,Harcken, Christian,Nabozny, Gerald,Thomson, David S.

, p. 6842 - 6851 (2011/12/22)

We report a SAR of non-steroidal glucocorticoid mimetics that utilize indoles as A-ring mimetics. Detailed SAR is discussed with a focus on improving PR and MR selectivity, GR agonism, and in vitro dissociation profile. SAR analysis led to compound (R)-33 which showed high PR and MR selectivity, potent agonist activity, and reduced transactivation activity in the MMTV and aromatase assays. The compound is equipotent to prednisolone in the LPS-TNF model of inflammation. In mouse CIA, at 30 mg/kg compound (R)-33 inhibited disease progression with an efficacy similar to the 3 mg/kg dose of prednisolone.

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