666751-73-1

Basic information

• Product Name: 3aH-Cyclopenta[b]furan-3a-carboxylicacid,hexahydro-6a-methoxy-,methylester(9CI)
• Synonyms: 3aH-Cyclopenta[b]furan-3a-carboxylicacid,hexahydro-6a-methoxy-,methylester(9CI)
• CAS NO: 666751-73-1
• Molecular Formula: C10H16O4
• Molecular Weight: 200.23
• Product Categories: METHOXY
• Mol File: 666751-73-1.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3aH-Cyclopenta[b]furan-3a-carboxylicacid,hexahydro-6a-methoxy-,methylester(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3aH-Cyclopenta[b]furan-3a-carboxylicacid,hexahydro-6a-methoxy-,methylester(9CI)(666751-73-1)
• EPA Substance Registry System: 3aH-Cyclopenta[b]furan-3a-carboxylicacid,hexahydro-6a-methoxy-,methylester(9CI)(666751-73-1)

Safety Data

• Hazardous Substances Data: 666751-73-1(Hazardous Substances Data)

Upstream product

• 54460-31-0 (+/-)-2-[1-(methoxycarbonyl)-2-oxocyclopentyl]ethyl acetate 
• 67-56-1 methanol 
• 10472-24-9 methyl 2-oxocyclopentane-1-carboxylate 

Relevant articles and documents

An efficient method for the synthesis of hydrocyclopenta[1,2-b]furan with various side chains at 3a-position

(3aS*,1aR*)-1a-Methoxy-3a-methoxycarbonyl-2,3,4,5,6, 3a-hexahydrocyclopenta[1,2-b]furan was prepared in 96% overall yield from 2-methoxycarbonylated cyclopenta-1-one in two steps. This furan derivative is used as a divergent intermediate in the synthesis of our originally designed chiral resolving agents having various substitutions. During the preliminary evaluation of divergent synthetic products, it was discovered that 3a-(fluoren-9-ylidenemethyl)-2,3,4,5,3a-pentahydrocyclopenta[1,2-b]furan, was a remarkably improved chiral resolving agent for secondary alcohols.

OPTICAL RESOLVER, PROCESS FOR PRODUCING OPTICALLY ACTIVE ISOMER, AND 1,5-SUBSTITUTED BICYCLO (3.3.0) -2-OXAOCTANE COMPOUND

An agent for optical resolution comprising a bicyclo [3.3.0] -2-oxaoctane compound represented by the formula [1], [2] or [3] ; a process for producing an optically active substance comprising obtaining a mixture of diastereomers by reaction of the agent with a mixture of optically active substances having active hydrogen atom, resolving the mixture of diastereomers into each diastereomer and obtaining an (R) optically active substance or an (S) optically active substance by decomposition of the diastereomer; and compounds represented by the above formulae in which R11 represents fluorenylmethyl group, fluorenylidenemethyl group, bis(4-cyclohexylphenyl)methyl group, 4-(9-phenanthryl)phenyl group, 4-(1-pyrenyl)phenyl group, 4-(5-acenaphthenyl)phenyl group or 4-(9-anthryl)phenyl group, are disclosed. A useful optically active substance having a very high purity can be produced efficiently by using the agent of the present invention.

2-OXABICYCLO 3.3.0 OCTANE COMPOUNDS, PROCESS FOR PRODUCING THE SAME, OPTICAL RESOLVER, METHOD OF SEPARATING DIASTEREOMER MIXTURE, AND METHOD OF OPTICALLY RESOLVING ALCOHOL

2-Oxabicyclo[3.3.0]octane compounds represented by the following formula (1) (compound (1)); an optical resolver comprising at least one of the compounds (1); a process for producing the compounds (1) which comprises reacting a compound (2) or compound (3) with an alcohol (5) in the presence of an acid catalyst; a method of separating a diastereomer mixture of a compound (1); and a method of optically resolving an alcohol with the optical resolver. [In the formulae, R1 to R10 each represents hydrogen atom, etc.; R11 represents an alkyl group, etc.; R12 represents a hydrocarbon group, etc.; R13 represents a hydrocarbon group, etc.; and A represents acetyl group, etc.]