666861-29-6

Basic information

• Product Name: [5-(4-Methoxyphenyl)-2-thienyl]boronic acid
• Synonyms: [5-(4-Methoxyphenyl)-2-thienyl]boronic acid;(5-(4-methoxy phenyl)thiophen -2-yl)boronic acid
• CAS NO: 666861-29-6
• Molecular Formula: C₁₁H₁₁BO₃S
• Molecular Weight: 234.07924
• Mol File: 666861-29-6.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: [5-(4-Methoxyphenyl)-2-thienyl]boronic acid(CAS DataBase Reference)
• NIST Chemistry Reference: [5-(4-Methoxyphenyl)-2-thienyl]boronic acid(666861-29-6)
• EPA Substance Registry System: [5-(4-Methoxyphenyl)-2-thienyl]boronic acid(666861-29-6)

Safety Data

• Hazardous Substances Data: 666861-29-6(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
[5-(4-Methoxyphenyl)-2-thienyl]boronic acid is used as a building block for the synthesis of complex organic molecules. Its ability to react with various organic compounds, such as alcohols and amines, through boronic acid coupling, makes it a valuable reagent in creating diverse molecular structures.
Used in Medicinal Chemistry:
In the pharmaceutical industry, [5-(4-Methoxyphenyl)-2-thienyl]boronic acid is utilized as a key intermediate in the development of new drugs. Its unique structure and reactivity contribute to the design and synthesis of potential therapeutic agents.
Used in Agrochemicals:
[5-(4-Methoxyphenyl)-2-thienyl]boronic acid is also employed in the agrochemical sector, where it serves as a precursor for the synthesis of various agrochemical compounds, including pesticides and herbicides.
Used in Cancer Treatment Research:
[5-(4-Methoxyphenyl)-2-thienyl]boronic acid has been studied for its potential therapeutic applications, particularly in the treatment of cancer. Its unique chemical properties may offer new avenues for the development of targeted cancer therapies.

Upstream product

• 54095-24-8 5-(4-methoxylphenyl)-2-bromothiophene 
• 42545-43-7 2-(4-methoxyphenyl)thiophene 
• 5419-55-6 Triisopropyl borate 
• 7732-18-5 water 
• 5720-07-0 4-methoxyphenylboronic acid 

Downstream Products

• 666861-41-2 4-{5-[4-(6-acryloyloxy-hexyloxy)-phenyl]-thiophen-2-yl}biphenyl-4-carboxylic acid 6-acryloyloxy-hexyl ester 

Relevant articles and documents

Effect of Thiophene Spacer Position in Carbazole-Based Dye-Sensitized Solar Cells on Photophysical, Electrochemical and Photovoltaic Properties

The synthesis, photophysical and electrochemical properties, and photovoltaic performances in dye-sensitized solar cells (DSSCs) of five new metal-free organic sensitizers with a carbazole moiety as the electron donor are reported. The compounds contain a thiophene at various positions and a cyanoacrylic acid unit as the electron acceptor. The position of the thiophene moiety affected both the photophysical and electrochemical properties, leading to conversion efficiencies of 1.44 to 4.57 % under AM 1.5 solar conditions (100 mW cm–2). The best performance and longest electron lifetime were found when a thiophene was located on both donor and acceptor sites. The DSSC showed a short-circuit current (Jsc) of 8.59 mA/cm2, an open-circuit photovoltage (Voc) of 0.75 V, and a fill factor (FF) of 0.71. The position of the π-conjugated bridges not only affects the absorption spectra and the energy levels of the sensitizers, but also adjusts the electron lifetime.

New insights into the SAR and binding modes of bis(hydroxyphenyl)thiophenes and -benzenes: Influence of additional substituents on 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1) inhibitory activity and selectivity

17β-Hydroxysteroid dehydrogenase type 1 (17β-HSD1) is responsible for the catalytic reduction of weakly active E1 to highly potent E2. E2 stimulates the proliferation of hormone-dependent diseases via activation of the estrogen receptor α (ERα). Because o