668484-45-5

Basic information

• Product Name: 2-[1-(TERT-BUTOXYCARBONYL)-4-PIPERIDINYL]-1,3-THIAZOLE-4-CARBOXYLIC ACID
• Synonyms: 2-(PIPERDIN-4-YL)-1,3-THIAZOLE-4-CARBOXYLIC ACID, N1-BOC PROTECTED;2-[1-(TERT-BUTOXYCARBONYL)PIPERDIN-4-YL]-1,3-THIAZOLE-4-CARBOXYLIC ACID;2-[1-(TERT-BUTOXYCARBONYL)-4-PIPERIDINYL]-1,3-THIAZOLE-4-CARBOXYLIC ACID;2-[1-(tert-butoxycarbonyl)piperid-4-yl]-1,3-thiazole-4-carboxylic acid;2-[1-(tert-butoxycarbonyl)piperidin-4-yl]-1,3-thiazole-4-carboxylic acid;1-(tert-Butoxycarbonyl)-4-(4-carboxy-1,3-thiazol-2-yl)piperidine, 2-[1-(tert-Butoxycarbonyl)piperidin-4-yl]-4-carboxy-1,3-thiazole
• CAS NO: 668484-45-5
• Molecular Formula: C14H20N2O4S
• Molecular Weight: 312.38
• Mol File: 668484-45-5.mol

Chemical Properties

• Melting Point: 162 °C
• Boiling Point: 0°C
• Flash Point: 0°C
• Appearance: /
• Density: 1.279g/cm³
• Vapor Pressure: 1.04E-09mmHg at 25°C
• Refractive Index: 1.563
• Storage Temp.: 2-8°C
• PKA: 1.35±0.10(Predicted)
• CAS DataBase Reference: 2-[1-(TERT-BUTOXYCARBONYL)-4-PIPERIDINYL]-1,3-THIAZOLE-4-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[1-(TERT-BUTOXYCARBONYL)-4-PIPERIDINYL]-1,3-THIAZOLE-4-CARBOXYLIC ACID(668484-45-5)
• EPA Substance Registry System: 2-[1-(TERT-BUTOXYCARBONYL)-4-PIPERIDINYL]-1,3-THIAZOLE-4-CARBOXYLIC ACID(668484-45-5)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36
• HazardClass: IRRITANT
• Hazardous Substances Data: 668484-45-5(Hazardous Substances Data)

Usage

Uses

Used in Medicinal Chemistry:
2-[1-(TERT-BUTOXYCARBONYL)-4-PIPERIDINYL]-1,3-THIAZOLE-4-CARBOXYLIC ACID is used as a key intermediate in the synthesis of pharmaceuticals for targeting specific biological pathways. Its unique structure allows for the creation of molecules with potential therapeutic effects.
Used in Drug Discovery and Development:
In the pharmaceutical industry, 2-[1-(TERT-BUTOXYCARBONYL)-4-PIPERIDINYL]-1,3-THIAZOLE-4-CARBOXYLIC ACID is utilized as a building block for the development of new drugs. Its versatility in chemical synthesis and potential for biological activity make it a valuable asset in the creation of novel therapeutic agents.
Used in Chemical Synthesis:
2-[1-(TERT-BUTOXYCARBONYL)-4-PIPERIDINYL]-1,3-THIAZOLE-4-CARBOXYLIC ACID is used as a synthetic precursor in the preparation of more complex organic molecules. Its functional groups facilitate various chemical reactions, contributing to the synthesis of a diverse range of compounds with potential applications in different fields.
Used in Research and Exploration:
In the field of scientific research, 2-[1-(TERT-BUTOXYCARBONYL)-4-PIPERIDINYL]-1,3-THIAZOLE-4-CARBOXYLIC ACID is employed as a subject of study to explore its chemical reactivity and biological properties. Understanding its behavior in different conditions can lead to the discovery of new applications and insights into its role in drug development.

InChI:InChI=1/C14H20N2O4S/c1-14(2,3)20-13(19)16-6-4-9(5-7-16)11-15-10(8-21-11)12(17)18/h8-9H,4-7H2,1-3H3,(H,17,18)

Upstream product

• 867065-53-0 4-(4-ethoxycarbonylthiazol-2-yl)piperazine-1-carboxylic acid tert-butyl ester 
• 57260-71-6 1-t-Butoxycarbonylpiperazine 

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