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3-Amino-4-cyclopropyl-1H-pyrazole is a chemical compound with the molecular formula C5H7N3, belonging to the class of pyrazole derivatives. It is a heterocyclic compound that is frequently found in pharmaceuticals and agrochemicals due to its potential biological activity. 3-Amino-4-cyclopropyl-1H-pyrazole is notable for its role in the synthesis of various pharmaceuticals and its potential applications in treating a range of diseases.

673475-74-6

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673475-74-6 Usage

Uses

Used in Pharmaceutical Synthesis:
3-Amino-4-cyclopropyl-1H-pyrazole is used as a key intermediate in the synthesis of pharmaceuticals for its potential biological activity. It contributes to the development of new drugs with therapeutic benefits.
Used in Drug Research and Development:
In the pharmaceutical industry, 3-Amino-4-cyclopropyl-1H-pyrazole is utilized as a research compound for the exploration and development of novel drug candidates. Its presence in drug discovery pipelines underscores its importance in advancing medical treatments.
Used in Treatment of Diseases:
3-Amino-4-cyclopropyl-1H-pyrazole has been studied for its potential therapeutic applications in the treatment of various diseases, including cancer and inflammatory conditions. Its biological activity makes it a promising candidate for further research and potential clinical use.
Used in Agrochemicals:
Although not explicitly mentioned in the provided materials, given its common presence in agrochemicals, 3-Amino-4-cyclopropyl-1H-pyrazole may also be used in the development of agrochemical products, potentially for pest control or as a component in fertilizers, due to its chemical properties and reactivity.

Check Digit Verification of cas no

The CAS Registry Mumber 673475-74-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,7,3,4,7 and 5 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 673475-74:
(8*6)+(7*7)+(6*3)+(5*4)+(4*7)+(3*5)+(2*7)+(1*4)=196
196 % 10 = 6
So 673475-74-6 is a valid CAS Registry Number.
InChI:InChI=1/C6H9N3/c7-6-5(3-8-9-6)4-1-2-4/h3-4H,1-2H2,(H3,7,8,9)

673475-74-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-cyclopropyl-1H-pyrazol-5-amine

1.2 Other means of identification

Product number -
Other names 3-Amino-4-cyclopropyl-1H-pyrazole

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:673475-74-6 SDS

673475-74-6Downstream Products

673475-74-6Relevant articles and documents

TRISUBSTITUTED PYRAZOLO [1,5-A] PYRIMIDINE COMPOUNDS AS CDK7 INHIBITORS

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Page/Page column 66; 67, (2020/09/27)

Compounds having activity as cancer agents are provided. The compounds have the following structure (I) or a pharmaceutically acceptable salts, stereoisomers, tautomers, thereof, wherein R1, R2, R3 and L are as defined herein. This disclosure provides methods associated with preparation and use of such compounds, pharmaceutical compositions comprising such compounds, and methods for treating a CDK7-dependent disease (e.g., cancer).

INDOLE AHR INHIBITORS AND USES THEREOF

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Paragraph 00607; 00609, (2018/11/22)

The present invention provides compounds useful as inhibitors of AHR, compositions thereof, and methods of using the same.

6,7,8,9-TETRAHYDRO-5H-1,4,7,10A-TETRAAZA-CYCLOHEPT[F]INDENE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS, THEIR USE AND PROCESSES FOR PREPARING THEM

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Page/Page column 114, (2010/06/17)

The present invention relates to compounds defined by formula (I), wherein the groups X, Y, W and R 1 to R 4 are defined as in claim 1, possessing valuable pharmacological activity. Particularly the compounds are agonists of the 5-HT2C receptor, and thus are suitable for treatment and prevention of diseases which can be influenced by inhibition of this receptor, such as metabolic and CNS-related disorders

7-Aminopyrazolo[1,5-a]pyrimidines as potent multitargeted receptor tyrosine kinase inhibitors

Frey, Robin R.,Curtin, Michael L.,Albert, Daniel H.,Glaser, Keith B.,Pease, Lori J.,Soni, Niru B.,Bouska, Jennifer J.,Reuter, David,Stewart, Kent D.,Marcotte, Patrick,Bukofzer, Gail,Li, Junling,Davidsen, Steven K.,Michaelides, Michael R.

supporting information; experimental part, p. 3777 - 3787 (2009/04/07)

7-Aminopyrazolo[1,5-a]pyrimidine urea receptor tyrosine kinase inhibitors have been discovered. Investigation of structure-activity relationships of the pyrazolo[1,5-a]pyrimidine nucleus led to a series of 6-(4-N,N′-diphenyl) ureas that potently inhibited

PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS

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Page/Page column 31, (2008/06/13)

In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.

PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS

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Page 29-30, (2008/06/13)

In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.

PYRAZOLOPYRIMIDINES AS CYCLIN-DEPENDENT KINASE INHIBITORS

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Page 52, (2008/06/13)

In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.

PYRAZOLOPYRIMIDINES AND THE USE THEREOF FOR CONTROLLING HARMFUL ORGANISMS

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Page 105,106, (2010/11/30)

The invention relates to novel pyrazolopyrimidines of formula (I) wherein R1, R2, R3, X1 and X2 have the designations cited in the description, to a method for producing said substances, and to the use of the same for controlling harmful organisms. The invention also relates to novel intermediates of formulae (II), (V) and (VI), and to methods for producing the same.

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