- Preparation method N-substituted piperidine -3- ketone (by machine translation)
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The invention provides N -substituted piperi- 3 3-ketone preparation method, which uses acrylonitrile (II) and nitromethane as raw materials to obtain 4 -substituted-N-alkoxycarbonylmethyl- 4 4-aminobutyronitrile (III), to obtain 4 - substituent - N N-alkoxycarbonylmethyl( (IV),substituted-piperi- 3 3-one N - by addition reaction and decarboxylation to yield (V),substituted-piperidin-3-one according. to the present invention by two-time substituent reaction, reaction, and decarboxylation to obtain, a compound obtained from, N -substituted-piperidin-3-one of, the invention. (I). The method is simple, process and, times of reaction and decarboxylation. (by machine translation)
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Paragraph 0094-0097
(2020/03/25)
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- Daucus carota mediated-reduction of cyclic 3-oxo-amines
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Carrots (Daucus carota) were used to reduce cyclic amino-ketones in high yields and enantiomeric excesses. This cheap, eco-compatible, and efficient reducing reagent allows the easy access to precursors of biologically active products.
- Lacheretz, Romain,Pardo, Domingo Gomez,Cossy, Janine
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supporting information; experimental part
p. 1245 - 1248
(2009/08/08)
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