674804-66-1

Basic information

• Product Name: Ethanone, 1-(3a,5,6,6a-tetrahydro-4H-cyclopent[d]isoxazol-3-yl)- (9CI)
• Synonyms: Ethanone, 1-(3a,5,6,6a-tetrahydro-4H-cyclopent[d]isoxazol-3-yl)- (9CI)
• CAS NO: 674804-66-1
• Molecular Formula: C8H11NO2
• Molecular Weight: 153.17844
• Product Categories: CYCLOPENTANE;ACETYLGROUP
• Mol File: 674804-66-1.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Ethanone, 1-(3a,5,6,6a-tetrahydro-4H-cyclopent[d]isoxazol-3-yl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(3a,5,6,6a-tetrahydro-4H-cyclopent[d]isoxazol-3-yl)- (9CI)(674804-66-1)
• EPA Substance Registry System: Ethanone, 1-(3a,5,6,6a-tetrahydro-4H-cyclopent[d]isoxazol-3-yl)- (9CI)(674804-66-1)

Safety Data

• Hazardous Substances Data: 674804-66-1(Hazardous Substances Data)

Upstream product

• 67-64-1 acetone 
• 142-29-0 cyclopentene 

Relevant articles and documents

A convenient and efficient one-pot synthesis of 3-acylisoxazoles using iron(III) salts

3-Acylisoxazoles were synthesized by the reaction of alkenes or alkynes with ketones (acetone or acetophenone), as both a reagent and the solvent, by three methods: iron(III) nitrate under reflux, iron(III) salt-nitrogen dioxide (NO2) at room temperature,

Formation of isoxazole derivatives via nitrile oxide using ammonium cerium nitrate (CAN): A novel one-pot synthesis of 3-acetyl- and 3-benzoylisoxazole derivatives

The reactions of alkenes and alkynes with ammonium cerium(IV) nitrate ((NH4)2Ce(NO3)6, CAN(IV)) in acetone under reflux gave the corresponding 3-acetyl-4,5-dihydroisoxazole and 3-acetylisoxazole derivatives. In the case of acetophenone, 3-benzoyl-4,5- dihydroisoxazole and 3-benzoylisoxazole derivatives were obtained. Reaction of acetone with CAN(IV) afforded the corresponding furoxan (3,4-diacetyl-1,2,5- oxadiazole 2-oxide) as the dimer of nitrile oxide. Moreover, it was found that yields of isoxazole derivatives were improved using ammonium cerium(III) nitrate tetrahydrate ((NH4)2Ce(NO3) 5·4H2O, CAN(III))-formic acid. The reaction mechanisms based on nitration and formation of nitrile oxide mediated by CAN(IV) or CAN(III) from acetone or acetophenone are also proposed.