675827-10-8

Basic information

• Product Name: 5-BROMO-1-ISOPROPYL-1H-INDOLE
• Synonyms: 5-BROMO-1-ISOPROPYL-1H-INDOLE
• CAS NO: 675827-10-8
• Molecular Formula: C₁₁H₁₂BrN
• Molecular Weight: 238.127
• Mol File: 675827-10-8.mol

Chemical Properties

• Boiling Point: 311.8±15.0 °C(Predicted)
• Appearance: /
• Density: 1.36±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 5-BROMO-1-ISOPROPYL-1H-INDOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-1-ISOPROPYL-1H-INDOLE(675827-10-8)
• EPA Substance Registry System: 5-BROMO-1-ISOPROPYL-1H-INDOLE(675827-10-8)

Safety Data

• Hazardous Substances Data: 675827-10-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
5-Bromo-1-isopropyl-1H-indole is used as a building block for the synthesis of various organic compounds. It serves as a key component in the development of potential drug candidates and research on new chemical entities.
Used in Medicinal Chemistry:
5-Bromo-1-isopropyl-1H-indole is used as a versatile compound for chemical and biological studies. Its structural diversity allows it to exhibit different biological activities, making it valuable in the discovery and development of new drugs and therapeutic agents.

Upstream product

• 10075-50-0 5-bromo-1H-indole 
• 75-26-3 isopropyl bromide 
• 75-30-9 2-iodo-propane 

Downstream Products

• 1289141-78-1 C₂₁H₂₀N₄O 

Relevant articles and documents

2,4-disubstituted pyrimidine derivative as CDK (cyclin-dependent protein kinases) inhibitor and application thereof

The invention relates to a 2,4-disubstituted pyrimidine derivative and application thereof as a treatment effective CDK (cyclin-dependent protein kinases) inhibitor. Particularly, the invention relates to a novel 2,4-disubstituted pyrimidine derivative shown by a general formula (I), a medicine composition thereof, and a purpose of the derivative as the selective CDK4/6 inhibitor to the prevention or treatment of diseases relevant to CDK4/6. The formula I is shown in the description.

THERAPEUTIC COMPOUNDS AND USES THEREOF

The present invention relates to compounds of formula (I): and to salts thereof, wherein A has any of the values defined in the specification, and compositions and uses thereof. The compounds are useful as inhibitors of CBP and/or EP300. Also included are pharmaceutical compositions comprising a compound of formula (I) or a pharmaceutically acceptable salt thereof, and methods of using such compounds and salts in the treatment of various CBP and/or EP300-mediated disorders.

GLUCOSYLCERAMIDE SYNTHASE INHIBITORS FOR THE TREATMENT OF DISEASES

Described herein are compounds of Formula I, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or conditions associated with the enzyme glucosylceramide synthase (GCS).