675843-82-0

Basic information

• Product Name: 1-(2-Hydroxy-ethyl)-4,6-dimethyl-2-oxo-1,2-dihydro-pyridine-3-carbonitrile
• Synonyms: 1-(2-Hydroxy-ethyl)-4,6-dimethyl-2-oxo-1,2-dihydro-pyridine-3-carbonitrile
• CAS NO: 675843-82-0
• Molecular Formula: C10H12N2O2
• Molecular Weight: 192.21448
• Mol File: 675843-82-0.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(2-Hydroxy-ethyl)-4,6-dimethyl-2-oxo-1,2-dihydro-pyridine-3-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-Hydroxy-ethyl)-4,6-dimethyl-2-oxo-1,2-dihydro-pyridine-3-carbonitrile(675843-82-0)
• EPA Substance Registry System: 1-(2-Hydroxy-ethyl)-4,6-dimethyl-2-oxo-1,2-dihydro-pyridine-3-carbonitrile(675843-82-0)

Safety Data

• Hazardous Substances Data: 675843-82-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1-(2-Hydroxy-ethyl)-4,6-dimethyl-2-oxo-1,2-dihydro-pyridine-3-carbonitrile is used as a key intermediate in the synthesis of pharmaceutical drugs for its potential to contribute to the development of new medications for treating a range of diseases. Its unique chemical structure allows for the creation of complex organic molecules that can be tailored for specific therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 1-(2-Hydroxy-ethyl)-4,6-dimethyl-2-oxo-1,2-dihydro-pyridine-3-carbonitrile serves as a crucial component in the production of various agrochemicals. Its incorporation aids in the development of effective compounds for crop protection and enhancement of agricultural yields.
Further research and development of 1-(2-Hydroxy-ethyl)-4,6-dimethyl-2-oxo-1,2-dihydro-pyridine-3-carbonitrile may pave the way for the discovery of additional drugs and other beneficial products, highlighting its importance in both the pharmaceutical and agrochemical industries.

Upstream product

• 15029-40-0 2-cyano-N-(2-hydroxyethyl)acetamide 
• 123-54-6 acetylacetone 
• 748158-50-1 2-[(2-acetoxyethoxymethoxy)]-4,6-dimethylpyridine-3-carbonitrile 
• 748158-51-2 4,6-dimethyl-2-(2-hydroxyethoxymethoxy)pyridine-3-carbonitrile 
• 769-28-8 3-Cyano-4,6-dimethyl-2(1H)-pyridon 
• 748158-63-6 1-(2-acetoxyethyl)-4,6-dimethyl-2-oxo-1,2-dihydropyridine-3-carbonitrile 

Relevant articles and documents

Continuous flow synthesis of some 6- And 1,6-substituted 3-cyano-4-methyl-2-pyridones

In this study, six 6- and 1,6-substituted-3-cyano-4-methyl-2-pyri-dones were synthesized in a continuous flow microreactor system. The syntheses were realized at room temperature and the obtained results were compared to those achieved within classical syntheses. In order to optimize the continuous flow syntheses and increase the yield of the products, the retention time in the microreactor was varied by changing the flow rates of the reactant solutions. Furthermore, the reaction was optimized for 3-cyano-4,6-dimethyl-2-pyridone and 3-cyano-6-hydroxy-4-methyl-2-pyridone, which are comercially important in the pharmaceutical and dye industries. Both 2-pyridones were obtained in satisfactory yield of circa 60 % in less than 10 min. The resulting compounds were characterized by their melting points, FT-IR, 1H-NMR and UV–Vis spectra. The efficiency of the presented method for the synthesis of 2-pyridone-based molecules has promising potential for industrial production.

Alkylation of 2-pyridinones: Synthesis of novel acyclonucleosides

This paper presents the synthesis of some novel acyclonucleosides containing 2-pyridinones and 2-hydroxyethoxymethyl, 2,3-dihydroxy-propyl side chain. The tosylate of these nucleosides analogues could be modified to azido derivatives. Also, acyclonucleosides with 1-ethoxymethyl, 1-benzyloxymethyl, 1-methylthiomethyl and 2-hydroxyethyl side chains have been investigated. The O-alkylated pyridine derivatives were obtained during most reactions.