678144-48-4

Basic information

• Product Name: 8-Oxabicyclo[5.1.0]octane, 2-methylene-
• Synonyms: 8-Oxabicyclo[5.1.0]octane, 2-methylene-
• CAS NO: 678144-48-4
• Molecular Formula: C8H12O
• Molecular Weight: 124.18
• Mol File: 678144-48-4.mol

Chemical Properties

• Boiling Point: 171.8±19.0 °C(Predicted)
• Appearance: /
• Density: 0.98±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 8-Oxabicyclo[5.1.0]octane, 2-methylene-(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Oxabicyclo[5.1.0]octane, 2-methylene-(678144-48-4)
• EPA Substance Registry System: 8-Oxabicyclo[5.1.0]octane, 2-methylene-(678144-48-4)

Safety Data

• Hazardous Substances Data: 678144-48-4(Hazardous Substances Data)

Upstream product

• 57260-82-9 8-oxabicyclo[5.1.0]octane-2-one 
• 1779-49-3 Methyltriphenylphosphonium bromide 

Downstream Products

• 678144-55-3 (R)-3-propyl-2-cyclohepten-1-ol 
• 678144-55-3 (S)-3-propyl-2-cyclohepten-1-ol 
• 678144-56-4 (1R,2R)-2-ethyl-3-methylidenecycloheptan-1-ol 
• 678144-56-4 (1S,2S)-2-ethyl-3-methylidenecycloheptan-1-ol 

Relevant articles and documents

Tandem reactions with chiral enolates: Preparation of allylic alcohols via trapping with vinyl oxiranes

[Chemical equation presented] An opening of vinyl oxiranes has been accomplished with Zn and Al enolates resulting from asymmetric conjugate addition reactions on cyclic enones. This novel tandem procedure affords the adducts In moderate to good yields, enantioselectivities up to 98%, and moderate to good cis/trans selectivities. This provides potentially useful synthetic substrates to prepare complex bicyclic compounds.

Catalytic Regiodivergent Kinetic Resolution of Allylic Epoxides: A New Entry to Allylic and Homoallylic Alcohols with High Optical Purity

A novel regiodivergent kinetic resolution of a series of allylic epoxides with alkylzinc reagents is described. Results demonstrate the potential of chiral copper-phosphoramidite catalysts for enantiomer differentiation of allylic epoxides, allowing a chiral catalyst-stereoregulated synthesis of cyclic allylic and homoallylic alcohols with high optical purities.