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2-(2,2-Dimethyl-2,3-dihydro-benzofuran-7-yloxy)-ethylamine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

680203-71-8

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  • 2-((2,2-Dimethyl-2,3-dihydrobenzofuran-7-yl)oxy)ethanamine hydrochloride

    Cas No: 680203-71-8

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680203-71-8 Usage

Molecular Structure

2-(2,2-Dimethyl-2,3-dihydro-benzofuran-7-yloxy)-ethylamine consists of an ethylamine group attached to a benzofuran molecule, which contains a benzene ring fused to a furan ring.

Substitution

The benzofuran portion of the molecule is substituted with two methyl groups and an ether functional group, contributing to its unique properties.

Potential Applications

This chemical compound has potential applications in pharmaceutical and chemical research due to its diverse chemical composition and potential biological activity.

Further Study

The specific properties and potential uses of 2-(2,2-Dimethyl-2,3-dihydro-benzofuran-7-yloxy)-ethylamine would require additional study and experimentation to be fully understood and utilized.

Check Digit Verification of cas no

The CAS Registry Mumber 680203-71-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,8,0,2,0 and 3 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 680203-71:
(8*6)+(7*8)+(6*0)+(5*2)+(4*0)+(3*3)+(2*7)+(1*1)=138
138 % 10 = 8
So 680203-71-8 is a valid CAS Registry Number.
InChI:InChI=1/C12H17NO2/c1-12(2)8-9-4-3-5-10(11(9)15-12)14-7-6-13/h3-5H,6-8,13H2,1-2H3

680203-71-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[(2,2-Dimethyl-2,3-dihydro-1-benzofuran-7-yl)oxy]ethanamine

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:680203-71-8 SDS

680203-71-8Downstream Products

680203-71-8Relevant articles and documents

Discovery of Novel pERK1/2- or β-Arrestin-Preferring 5-HT1AReceptor-Biased Agonists: Diversified Therapeutic-like versus Side Effect Profile

Sniecikowska, Joanna,Gluch-Lutwin, Monika,Bucki, Adam,Wi?ckowska, Anna,Siwek, Agata,Jastrzebska-Wiesek, Magdalena,Partyka, Anna,Wilczyńska, Daria,Pytka, Karolina,Latacz, Gniewomir,Przejczowska-Pomierny, Katarzyna,Wyska, El?bieta,Weso?owska, Anna,Paw?owski, Maciej,Newman-Tancredi, Adrian,Kolaczkowski, Marcin

supporting information, p. 10946 - 10971 (2020/11/09)

Novel 1-(1-benzoylpiperidin-4-yl)methanamine derivatives with high affinity and selectivity for serotonin 5-HT1A receptors were obtained and tested in four functional assays: ERK1/2 phosphorylation, adenylyl cyclase inhibition, calcium mobilization, and β-arrestin recruitment. Compounds 44 and 56 (2-methylaminophenoxyethyl and 2-(1H-indol-4-yloxy)ethyl derivatives, respectively) were selected as biased agonists with highly differential "signaling fingerprints"that translated into distinct in vivo profiles. In vitro, 44 showed biased agonism for ERK1/2 phosphorylation and, in vivo, it preferentially exerted an antidepressant-like effect in the Porsolt forced swimming test in rats. In contrast, compound 56 exhibited a first-in-class profile: it preferentially and potently activated β-arrestin recruitment in vitro and potently elicited lower lip retraction in vivo, a component of "serotonergic syndrome". Both compounds showed promising developability properties. The presented 5-HT1A receptor-biased agonists, preferentially targeting various signaling pathways, have the potential to become drug candidates for distinct central nervous system pathologies and possessing accentuated therapeutic activity and reduced side effects.

Delta-aminoalkylbenzofuranol ethers, and preparation method and application thereof

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Paragraph 0064-0067, (2018/04/01)

The invention relates to delta-aminoalkylbenzofuranol ethers represented by chemical structural formula I shown in the description, and an application thereof in the preparation of herbicides. In thechemical structural formula I, R is selected from C1-C2 alkyl groups, and n is selected from 2, 3 and 4.

N-[(dihydrobenzofuran-7-yloxyl)alkyl]-2-aryloxy amide derivatives

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Paragraph 0027; 0028; 0029; 0034, (2017/12/27)

The invention discloses N-[( dihydrobenzofuran-7-yloxyl)alkyl]-2-aryloxy amide derivatives which are represented as a structural formula I and a structural formula II, and in the structural formula I or II, R is selected from a group consisting of H, C1-C2 alkyl, C3-C4 linear alkyl and C3-C4 branched alkyl; n is selected from a group consisting of 1,2,3,4,5 and 6; Y is selected from a group consisting of H, C1-C2 alkyl, F, Cl, Br and I; Y is selected from a group consisting of H, C1-C2 alkyl, F, Cl, Br, I, trifluoromethyl and trifluoroethyl; and Y is selected from a group consisting of H, C1-C2 alkyl, F, Cl, Br and I. The invention also provides an application of the N-[(dihydrobenzofuran-7-yloxyl)alkyl]-2-aryloxy amide derivatives to preparing herbicides.

Towards a new generation of potential antipsychotic agents combining D 2 and 5-HT1A receptor activities

Cuisiat, Stephane,Bourdiol, Nathalie,Lacharme, Vincent,Newman-Tancredi, Adrian,Colpaert, Francis,Vacher, Bernard

, p. 865 - 876 (2007/10/03)

We report the discovery and the synthesis of novel, potential antipsychotic compounds combining potent dopamine D2 receptor antagonist and serotonin 5-HT1A receptor agonist properties in the same molecule. We describe the structure-a

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