1563-38-8

Basic information

• Product Name: 2,3-Dihydro-2,2-dimethyl-7-benzofuranol
• Synonyms: 2,2-Dimethyl-2,3-dihydro-1-benzofuran-7-ol;2,3-dihydro-2,2-dimethyl-3,7-benzofurandiol;2,3-dihydro-2,2-dimethyl-3-hydroxphenolmethylcarbamate-7-benzofuranol;2,3-dihydro-2,2-dimethyl-7-benzofurano;3,7-benzofurandiol,2,3-dihydro-2,2-dimethyl-;Carbofuran 7-phenol;Carbofuran-7-ol;carbofuran7-phenol
• CAS NO: 1563-38-8
• Molecular Formula: C₁₀H₁₂O₂
• Molecular Weight: 164.2
• EINECS: 216-350-4
• Product Categories: Miscellaneous;Furan&Benzofuran;Alphabetic;D;DID - DINEnvironmental Standards;Metabolites;Pesticides&Metabolites;Benzofurans;Building Blocks;Heterocyclic Building Blocks
• Mol File: 1563-38-8.mol
• Article Data: 18

Chemical Properties

• Boiling Point: 95°C 1mm
• Flash Point: >230 °F
• Appearance: white crystalline solid
• Density: 1.101 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.839mmHg at 25°C
• Refractive Index: n20/D 1.541(lit.)
• Storage Temp.: 2-8°C
• Solubility: Chloroform (Slightly), Methanol (Sparingly)
• PKA: 10.10±0.40(Predicted)
• CAS DataBase Reference: 2,3-Dihydro-2,2-dimethyl-7-benzofuranol(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-Dihydro-2,2-dimethyl-7-benzofuranol(1563-38-8)
• EPA Substance Registry System: 2,3-Dihydro-2,2-dimethyl-7-benzofuranol(1563-38-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• RIDADR: UN 3082 9 / PGIII
• WGK Germany: 3
• RTECS: DF7708985
• Hazardous Substances Data: 1563-38-8(Hazardous Substances Data)

Usage

Chemical Properties

Colorless liquid

Uses

2,3-Dihydro-2,2-dimethyl-7-benzofuranol was used as starting reagent in the preparation of aminoalkanol derivatives of 2,3-dihydro-2,2-dimethyl-7-benzofuranol.

General Description

Odorless, white crystalline solid.

Reactivity Profile

2,3-Dihydro-2,2-dimethyl-7-benzofuranol is a carbamate ester. Carbamates are chemically similar to, but more reactive than amides. Like amides they form polymers such as polyurethane resins. Carbamates are incompatible with strong acids and bases, and especially incompatible with strong reducing agents such as hydrides. Flammable gaseous hydrogen is produced by the combination of active metals or nitrides with carbamates. Strongly oxidizing acids, peroxides, and hydroperoxides are incompatible with carbamates.

InChI:InChI=1/C8H4F3NO2/c9-8(10,11)14-7-3-1-6(2-4-7)12-5-13/h1-4H

Synthetic route

methallylpyrocatechol → 2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8)

Conditions	Yield
With iodine In dichloromethane for 0.5h; Ambient temperature;	84%

ortho-methallylpyrocatechol (4790-71-0) → 2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8)

Conditions	Yield
With C10H11O2(1-)*C3H4O3(2-)*Al(3+) In 2-methoxy-ethanol at 155 - 165℃; for 3h; Reagent/catalyst;	81.6%

2,3-dihydro-2,2-dimethyl-7-benzofuranol methylcarbamate (1563-66-2) → 2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8)

Conditions	Yield
With potassium hydroxide In ethanol	77%
With sodium hydroxide In water at 70℃; for 1h;

benzene-1,2-diol (120-80-9) + 3-Chloro-2-methylpropene (563-47-3) → 2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8)

Conditions	Yield
In toluene at 144.84℃; for 4h; Reagent/catalyst; Temperature; Time; Autoclave;	76.2%

toluene-4-sulfonic acid (104-15-4) + 2-isobutenyl-6-chlorophenol (53889-58-0) → 2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8)

Conditions	Yield
With sodium hydroxide In benzene	67%

2,3-dihydro-2,2-dimethyl-7-benzofuranol methylcarbamate (1563-66-2) → 2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8) + 3-isobutenyl-1,2-dihydroxybenzene + 3-(2-hydroxy-2 methylpropyl) benzene-1,2-diol

Conditions	Yield
With dissolved organic matter at 28℃; Kinetics; Further Variations:; Reaction partners; Decomposition; UV-irradiation;

2,3-dihydro-2,2-dimethyl-7-benzofuranol methylcarbamate (1563-66-2) → 2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8) + carbon dioxide (124-38-9) + methylamine (74-89-5)

Conditions	Yield
With borate buffer; cetyltrimethylammonim bromide In water at 100℃; for 0.00833333h; pH=9.0; Product distribution; Further Variations:; Temperatures; Decomposition;

2,3-dihydro-2,2-dimethyl-7-benzofuranol methylcarbamate (1563-66-2) → 2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8) + 2,3-dihydro-2,2-dimethyl-3-oxobenzofuran-7-ol (17781-16-7) + 2,3-dihydro-2,2-dimethylbenzofuran-7-yl formate + 2,3-dihydro-3-hydroxy-2,2-dimethylbenzofuran-7-ol

Conditions	Yield
With dihydrogen peroxide; iron; sodium chloride In water at 25℃; Activation energy; Product distribution; Further Variations:; Temperatures; Electrolysis;

2,3-dihydro-2,2-dimethyl-7-benzofuranol methylcarbamate (1563-66-2) → 2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8) + N-methyl-carbamic acid (6414-57-9)

Conditions	Yield
With sodium hydroxide; Sulfuric acid, monodecyl ester, sodium salt at 25℃; Kinetics; Further Variations:; Reagents;

2-(2-hydroxy-2-methylpropoxy) phenol (107189-19-5) → 2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8)

Conditions	Yield
With pyridine hydrochloride
toluene-4-sulfonic acid In toluene

phosphoric acid (H3 PO4) + benzene-1,2-diol (120-80-9) + isobutyraldehyde (78-84-2) → 2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8)

85%-phosphoric acid (H3 PO4) + benzene-1,2-diol (120-80-9) + isobutyraldehyde (78-84-2) → 2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8)

Conditions	Yield
With zinc diacetate In water; toluene
In water; toluene

benzene-1,2-diol (120-80-9) + dimethyl sulfate (77-78-1) + 3-Chloro-2-methylpropene (563-47-3) → 2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8)

Conditions	Yield
With sodium hydroxide In water

benzene-1,2-diol (120-80-9) → 2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8)

2,2-dichloro-6-chloro-6-(1-chloroisobutyl)cyclohexanone → 2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8)

Conditions	Yield
With hydrogenchloride; sodium acetate; acetic acid; copper(I) chloride In water; benzene

carbosulfan (55285-14-8) → 3-Hydroxycarbofuran (16655-82-6) + 2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8) + 2,3-dihydro-2,2-dimethyl-7-benzofuranol methylcarbamate (1563-66-2) + 2,3-dihydro-2,2-dimethyl-3-oxobenzofuran-7-ol (17781-16-7) + 2,3-dihydro-3-oxo-2,2-dimethylbenzofuran-7-yl methylcarbamate (16709-30-1) + C20H32N2O4S (1260117-81-4) + dibutylamine (111-92-2) + 2,3-dihydro-3-hydroxy-2,2-dimethylbenzofuran-7-ol

Conditions	Yield
With liver microsomal protein; NADPH In dimethyl sulfoxide at 37℃; pH=7.4; Kinetics; Reagent/catalyst; aq. phosphate buffer; Enzymatic reaction;

...Expand

2,3-dihydro-2,2-dimethyl-7-benzofuranol methylcarbamate (1563-66-2) → 2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8) + 2,3-dihydro-2,2-dimethyl benzofuran-4,7-diol (131161-60-9)

Conditions	Yield
With oxygen In water pH=5.4; Photolysis;

benzene-1,2-diol (120-80-9) + 3-Chloro-2-methylpropene (563-47-3) → 2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8) + 4-(2-methylallyl)-1,2-dihydroxybenzene (1310466-22-8)

Conditions	Yield
Stage #1: benzene-1,2-diol; 3-Chloro-2-methylpropene With potassium carbonate In water; 4-methyl-2-pentanone at 130℃; for 2h; sealed autoclave reactor; Stage #2: With hydrogenchloride In water; 4-methyl-2-pentanone at 70℃; for 0.5h; pH=3 - 4; Stage #3: With aluminum isopropoxide In xylene at 180℃; sealed autoclave reactor;

benzene-1,2-diol (120-80-9) + 3-Chloro-2-methylpropene (563-47-3) → 2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8) + ortho-methallylpyrocatechol (4790-71-0)

Conditions	Yield
In toluene at 119.84℃; for 4h; Autoclave;

2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8) + acetic anhydride (108-24-7) → 2,2-dimethyl-2,3-dihydrobenzofuran-7-yl acetate (21620-95-1)

Conditions	Yield
With triethylamine In dichloromethane at 0 - 20℃; for 12h;	100%
With pyridine In dichloromethane at 20℃; for 18h;

2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8) + allyl bromide (106-95-6) → 2,2-dimethyl-7-(prop-2-enyloxy)-2,3-dihydrobenzofuran (87386-25-2)

Conditions	Yield
With potassium carbonate In acetone for 60h; Heating;	97%

2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8) → 2,2-dimethyl-2,3-dihydrobenzofuran-4,7-dione (84428-21-7)

Conditions	Yield
With potassiuim nitrosodisulfonate In ethanol; water at 20℃; for 1h;	95%
With potassium nitrososulfonate In ethanol; water for 0.166667h;	84%
With potassiuim nitrosodisulfonate; sodium acetate; acetic acid In methanol; water at 25℃; for 1h;

2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8) → C10H11BrO2 (1259401-35-8)

Conditions	Yield
With N-Bromosuccinimide In dichloromethane at -15℃; for 12h;	95%

N,N-phenylbistrifluoromethane-sulfonimide (37595-74-7) + 2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8) → 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl trifluoromethasulfonate (308110-31-8)

Conditions	Yield
With triethylamine In dichloromethane at 0 - 20℃;	94%

2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8) + 2-chloro-ethanol (107-07-3) → 2-(2,2-dimethyl-2,3-dihydrobenzofuran-7-oxy)ethanol

Conditions	Yield
With potassium carbonate In ethanol at 70℃; for 10h;	93.2%

2-iodo-propane (75-30-9) + 2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8) → 7-isopropoxy-2,2-dimethyl-2,3-dihydrobenzofuran (1346169-07-0)

Conditions	Yield
With potassium carbonate In acetone for 48h; Williamson synthesis; Reflux;	93%

2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8) + N,N-diethylcarbamyl chloride (88-10-8) → C15H21NO3 (1379516-35-4)

Conditions	Yield
With sodium hydride In 1,2-dimethoxyethane; mineral oil at 23℃; for 45h; Inert atmosphere;	92%
With sodium hydride In 1,2-dimethoxyethane; mineral oil at 23℃; for 45h;	92%

2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8) + chloroacetic acid ethyl ester (105-39-5) → C14H18O3

Conditions	Yield
With potassium carbonate; potassium iodide In N,N-dimethyl-formamide at 60℃;	90%

2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8) + chloroacetic acid ethyl ester (105-39-5) → ethyl 2-((2,2-dimethyl-2,3-2,3-dihydrobenzofuran-7-yl)oxy)acetate

Conditions	Yield
Stage #1: 2,3-dihydro-2,2-dimethylbenzofuran-7-ol With sodium hydride In N,N-dimethyl-formamide at 20℃; Cooling with ice; Stage #2: chloroacetic acid ethyl ester With potassium iodide In N,N-dimethyl-formamide at 80℃;	89%
With potassium carbonate In acetone for 4.5h; Reflux;
With potassium carbonate In acetone for 4h; Reflux;
With potassium carbonate; potassium iodide In N,N-dimethyl-formamide at 60℃;

titanium(IV) isopropylate (546-68-9) + 2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8) → titanium(IV)(diisopropoxo)bis(2,3-dihydro-2,2-dimethyl-benzofuranoxo)

Conditions	Yield
In tetrahydrofuran byproducts: (CH3)2CHO; (N2), ligand in THF treated dropwise with 0.5 equiv. of Ti complex, stirred at room temp. for 12 h; evapd.(vac.), rinzed twice (cold pentane);	85%

titanium(IV) isopropylate (546-68-9) + 2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8) → di[titanium(IV)(triisopropoxo)(2,3-dihydro-2,2-dimethyl-benzofuranoxo)] (928764-19-6)

Conditions	Yield
In tetrahydrofuran byproducts: (CH3)2CHO; (N2), ligand in THF treated dropwise with 1 equiv. of Ti complex, stirred at room temp. for 12 h; evapd.(vac.), rinzed twice (cold pentane);	85%

2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8) + methyl (E)-2-[2-(bromomethyl)phenyl]-2-(methoxyimino)acetate (133409-72-0) → (E)-2-(2-(((2,2-dimethyl-2,3-dihydrobenzofuran-7-yl)oxy)methyl)phenyl)-2-(methoxyimino)acetic acid methyl ester

Conditions	Yield
With potassium carbonate; potassium iodide In acetonitrile for 3h; Reflux;	85%

2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8) + carbonochloridic acid 1-chloro-ethyl ester (50893-53-3) → 2,2-Dimethyl-2,3-dihydro-1-benzofuran-7-yl 1-chloroethyl carbonate (101506-44-9)

Conditions	Yield
With pyridine In dichloromethane for 5h; Ambient temperature;	84%
With pyridine In dichloromethane; water	84%

2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8) + 1-bromo-3-propanol (627-18-9) → 3-(2,2-dimethyl-2,3-dihydrobenzofuran-7-oxy)propanol

Conditions	Yield
With potassium carbonate In ethanol at 70℃; for 7h;	83.2%

2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8) → 4,6-dibromo-2,2-dimethyl-2,3-dihydrobenzofuran-7-alcohol

Conditions	Yield
With bromine In chloroform at 20℃; for 1.5h;	83%
With bromine In chloroform at 0℃; for 1.5h;	83%
With bromine In chloroform at 25℃; for 2h;	67%
With bromine In chloroform at 0 - 20℃; for 2h;	67.3%
With bromine In chloroform at 20℃; for 1.5h;	45%

2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8) + 2-(3-bromopropyl)isoindole-1,3-dione (5460-29-7) → 2-(3-(2,2-dimethyl-2,3-dihydrobenzofuran-7-yloxy)propyl)isoindoline-1,3-dione

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 70℃; for 2h;	82.8%
With potassium carbonate In N,N-dimethyl-formamide at 70℃; for 2h;	82.8%

1,4-dibromo-butane (110-52-1) + 2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8) → 1-(2,2-dimethyl[2,3]dihydrobenzofuran-7-yloxy)-4-bromobutane (1094709-97-3)

Conditions	Yield
With tetrabutylammomium bromide; potassium carbonate; sodium hydroxide Reflux; Microwave irradiation;	82%

2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8) + 1,2-Epoxy-3-bromopropane (3132-64-7) → 7-(2,3-epoxypropoxy)-2,3-dihydro-2,2-dimethylbenzofuran (250289-99-7)

Conditions	Yield
With potassium carbonate at 20℃; for 25h; Heating;	80%

2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8) + 3,5-dimethylphenyl isocyanate (54132-75-1) → 2,2-dimethyl-2,3-dihydrobenzofuran-7-yl 3,5-dimethylphenylcarbamate

Conditions	Yield
With triethylamine In toluene Heating;	79%

2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8) + 2-(4-bromobutyl)isoindoline-1,3-dione (5394-18-3) → 2-(4-(2,2-dimethyl-2,3-dihydrobenzofuran-7-yloxy)butyl)isoindoline-1,3-dione

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 70℃; for 2h;	78.7%
With potassium carbonate In N,N-dimethyl-formamide at 70℃; for 3h;	78.7%

N-chloroacetyl-N-methylcarbamoyl chloride (96924-32-2) + 2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8) → 2,3-dihydro-2,2-dimethyl-7-benzofuranyl N-chloroacetyl-N-methylcarbamate (32515-39-2)

Conditions	Yield
In toluene	77%

2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8) + 4-Chloro-1-butanol (928-51-8) → 4-(2,2-dimethyl-2,3-dihydrobenzofuran-7-oxy)butanol (884604-54-0)

Conditions	Yield
With tetrabutylammomium bromide; potassium carbonate In acetone for 12h; Reflux;	76.2%

2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8) + acrylonitrile (107-13-1) → 3-[(2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl)oxy]propanenitrile

Conditions	Yield
With potassium carbonate In tert-butyl alcohol for 48h; Inert atmosphere; Reflux;	75.1%
With potassium carbonate In tert-butyl alcohol for 48h; Inert atmosphere; Reflux;	75.1%
With potassium carbonate In tert-butyl alcohol for 48h; Reflux; Inert atmosphere;	75.1%
With potassium carbonate In tert-butyl alcohol for 48h; Inert atmosphere; Reflux;	75.1%

titanium(IV) isopropylate (546-68-9) + 2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8) → Ti(2,3-dihydro-2,2-dimethyl-7-benzofuran(1-))4

Conditions	Yield
In toluene (under N2); toluene and ligand added to Ti(OCH(CH3)2)4, warmed to 100°C for 2 h, refluxed for 4 h, cooled; solvent removed under vac., toluene added, refluxed for 6 h, cooled, solvent removed under vac., hexane added, placed in freezer overnight, filtered, washed with cold hexane, dried under vac.;	75%

2,3-dihydro-2,2-dimethylbenzofuran-7-ol (1563-38-8) + carbonochloridic acid, chloromethyl ester (22128-62-7) → chloromethyl (2,2-dimethyl-2,3-dihydro-7-benzofuryl) carbonate (132905-88-5)

Conditions	Yield
With sodium hydroxide; adogen 464 In water; benzene at 5℃; for 0.666667h;	73.5%

Upstream product

• 1563-66-2 2,3-dihydro-2,2-dimethyl-7-benzofuranol methylcarbamate 
• 107189-19-5 2-(2-hydroxy-2-methylpropoxy)-phenol 
• 120-80-9 benzene-1,2-diol 
• 78-84-2 isobutyraldehyde 
• 89110-96-3 2,2-dichloro-6-chloro-6-(1-chloroisobutyl)cyclohexanone 
• 4790-71-0 ortho-methallylpyrocatechol 
• 563-47-3 3-Chloro-2-methylpropene 
• 55285-14-8 carbosulfan 
• 77-78-1 dimethyl sulfate 
• 104-15-4 toluene-4-sulfonic acid 
• 53889-58-0 2-isobutenyl-6-chlorophenol 
• 77391-95-8 methallylpyrocatechol 

Downstream Products

• 222641-43-2 benzyloxymethylcarbamic acid 2,2-dimethyl-2,3-dihydrobenzofuran-7-yl ester 
• 18999-70-7 hydroxymethylcarbamic acid 2,2-dimethyl-2,3-dihydrobenzofuran-7-yl ester 
• 17781-16-7 2,3-dihydro-3-oxo-2,2-dimethylbenzofuran-7-ol 
• 1563-66-2 2,3-dihydro-2,2-dimethyl-7-benzofuranol methylcarbamate 
• 1286763-02-7 C₁₆H₁₆O 
• 265119-94-6 2-((2,2-dimethyl-2,3-dihydrobenzofuran-7-yl)oxy)acetic acid 

Relevant articles and documents

Preparation of Lewis acid ionic liquids for one-pot synthesis of benzofuranol from pyrocatechol and 3-chloro-2-methylpropene

Several Lewis acid ionic liquids (LAILs) with different acidic scales were synthesised and used as catalysts for the synthesis of benzofuranol by condensation of pyrocatechol and 3-chloro-2-methylpropene in one pot. The catalytic activity of these ionic liquids was correlated with their Lewis acidity. Low to moderate conversion with excellent selectivity to benzofuranol was obtained in the presence of the appropriate LAILs. Compared to the two-step synthetic method currently used in industry, a higher yield plateau (81.1 %) of benzofuranol was achieved in the presence of [BMIm][AlCl4] IL as catalyst at 418 K after 4 h. Furthermore, the catalyst is readily separated from the resultant products via decantation and could be reused after treatment in vacuum.

Development of a biomimetic sensor modified with hemin and graphene oxide for monitoring of carbofuran in food

A biomimetic sensor based on a carbon paste electrode modified with hemin complex and graphene oxide was developed as an alternative technique for the sensitive and selective analysis of carbofuran pesticide. The electrochemical analysis of carbofuran was initially carried out with the biomimetic sensor using cyclic voltammetry within the potential range of -0.2 to 0.8 V vs. Ag/AgCl (KClsat). The sensor showed in square wave voltammetry (SWV) a linear response between 5.0 × 10-6 and 9.5 × 10-5 mol L-1, a sensitivity of 1.1 × 105 (±1.4 × 103) μA L mol-1 and detection limit of 9.0 × 10-9 mol L-1. The sensitive and selective detection of carbofuran was confirmed through the analysis of other pesticides using SWV. When the proposed sensor was applied in food samples, the results obtained in the recovery studies were found to be close to 100%. These results obtained were similar to those of the high performance liquid chromatography (HPLC) method. Furthermore, an electrochemical study was conducted aiming at verifying the importance of the use of hemin complex and graphene oxide in the construction of the sensor. The results obtained showed a clear improvement in selectivity, reproducibility and sensitivity of the proposed sensor.

Photodecomposition of the carbamate pesticide carbofuran: Kinetics and the influence of dissolved organic matter

This study examined the photodecomposition of carbofuran, a carbamate pesticide with high oral toxicity. Rate constants are measured for the pesticide in aqueous solution and in the presence of various samples of dissolved organic matter (DOM). Kinetic experiments are monitored with HPLC, while reaction products are determined using HPLC, GC-MS, and 1H NMR: mechanisms are proposed for the first three steps of the reaction. It was found that the photodecomposition proceeds via first-order reaction kinetics and that the presence of various DOM samples inhibits the photolysis reaction of carbofuran. This phenomenon can be correlated to the magnitude of the binding interaction between carbofuran and DOM. Finally, techniques such as GC-MS and 1H NMR are used to identify the photodecomposition products. The first three steps of the reaction are defined. In the first step of the reaction, the carbamate group is cleaved from the molecule. The furan moiety is opened in the second step producing a substituted catechol with a tert-butyl alcohol group as the substituent at the number three carbon. This molecule then undergoes a dehydration reaction to form an alkene side group from the tert-butyl alcohol side group.

PURIFICATION PROCESS FOR PARA-METHALLYLPYROCATECHOL

The present invention relates to a process for the purification of para-methallylpyrocatechol and to the preparation of flavor and fragrance compounds from para-methallylpyrocatechol.