680210-85-9

Basic information

• Product Name: 4-Chloro-3-cyano-1,2-dihydro-2-oxoquinoline
• Synonyms: 4-Chloro-1,2-dihydro-2-oxoquinoline-3-carbonitrile;4-Chloro-3-cyano-1,2-dihydro-2-oxoquinoline
• CAS NO: 680210-85-9
• Molecular Formula: C₁₀H₅ClN₂O
• Molecular Weight: 204.6125
• Mol File: 680210-85-9.mol

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 4-Chloro-3-cyano-1,2-dihydro-2-oxoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Chloro-3-cyano-1,2-dihydro-2-oxoquinoline(680210-85-9)
• EPA Substance Registry System: 4-Chloro-3-cyano-1,2-dihydro-2-oxoquinoline(680210-85-9)

Safety Data

• Hazardous Substances Data: 680210-85-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Synthesis:
4-Chloro-3-cyano-1,2-dihydro-2-oxoquinoline is used as a key intermediate in the synthesis of pharmaceuticals for its ability to be incorporated into the molecular structures of various drugs. Its unique functional groups allow for versatile chemical reactions, facilitating the development of new therapeutic agents.
Used in Agrochemical Production:
In the agrochemical industry, 4-Chloro-3-cyano-1,2-dihydro-2-oxoquinoline serves as an intermediate in the production of pesticides and other crop protection agents. Its chemical properties make it suitable for the creation of compounds that can effectively control pests and diseases in agriculture.
Used in Organic Compounds Synthesis:
4-Chloro-3-cyano-1,2-dihydro-2-oxoquinoline is also utilized in the synthesis of other organic compounds, including dyes and pigments, due to its reactive functional groups. Its presence in these compounds can enhance their color properties and improve their stability.
Used in Fine Chemicals Production:
4-Chloro-3-cyano-1,2-dihydro-2-oxoquinoline is employed as an intermediate in the production of fine chemicals, which are high-purity chemicals used in various applications such as research, pharmaceuticals, and specialty industries.
Used in Medicinal Chemistry Research:
With its potential biological activities, 4-Chloro-3-cyano-1,2-dihydro-2-oxoquinoline has attracted interest in the field of medicinal chemistry. Researchers are exploring its properties and potential uses in the development of new drugs and therapeutic agents.
However, it is important to note that further research is needed to fully understand the properties and potential uses of 4-Chloro-3-cyano-1,2-dihydro-2-oxoquinoline, ensuring its safe and effective application in various industries.

Upstream product

• 69875-54-3 2,4-Dichloroquinoline-3-carbonitrile 
• 118-48-9 isatoic anhydride 
• 15000-43-8 2,4-dihydroxyquinoline-3-carbonitrile 
• 15000-43-8 4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carbonitrile 

Downstream Products

• 16560-18-2 4-phenyl-2-oxo-1,2-dihydroquinoline-3-carbonitrile 

Relevant articles and documents

PHENYL-CYANOQUINOLINONE PDE9 INHIBITORS

The present invention is directed to phenylcyanoquinolinone compounds which may be useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 9 (PDE9). The present invention also relates to the use

AZA-CYANOQUINOLINONE PDE9 INHIBITORS

The present invention is directed to azacyanoquinolinone compounds which may be useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 9 (PDE9). The present invention also relates to the use of such compounds for treating neurological and psychiatric disorders, such as schizophrenia, psychosis or Huntington's disease, and those associated with striatal hypofunction or basal ganglia dysfunction.

OXY-CYANOQUINOLINONE PDE9 INHIBITORS

The present invention is directed to oxycyanoquinolinone compounds which may be useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 9 (PDE9). The present invention also relates to the use of

MODULATION OF CHEMOSENSORY RECEPTORS AND LIGANDS ASSOCIATED THEREWITH

The present invention provides screening methods for identifying modifiers of chemosensory receptors and their ligands, e.g., by determining whether a test entity is suitable to interact with one or more interacting sites within the Venus flytrap domains of the chemosensory receptors as well as modifiers capable of modulating chemosensory receptors and their ligands.

PYRAZOLOQUINOLONE DERIVATIVE AND USE THEREOF

The present invention provides a pyarzoloquinolone derivative having kinase inhibitory activity. The derivative is represented by the formula: wherein R1 is an aryl group which may be substituted, or an aromatic heterocyclic group which may be

INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR AND METHODS FOR IDENTIFYING THE SAME

Inhibitors of MIF are provided which have utility in the treatment of a variety of disorders, including the treatment of pathological conditions associated with MIF activity. The inhibitors of MIF have the following structures (Ia), (Ib) including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof, wherein n, R1, R2, R3, R4, X, and Z are as defined herein. Compositions containing an inhibitor of MIF in combination with a pharmaceutically acceptable carrier are also provided, as well as methods for use of the same.