680231-46-3

Basic information

• Product Name: Oxiranecarboxamide, N-(2-hydroxyphenyl)-3-phenyl-, (2R,3S)- (9CI)
• Synonyms: Oxiranecarboxamide, N-(2-hydroxyphenyl)-3-phenyl-, (2R,3S)- (9CI)
• CAS NO: 680231-46-3
• Molecular Formula: C₁₅H₁₃NO₃
• Molecular Weight: 255.26862
• Product Categories: AMIDE
• Mol File: 680231-46-3.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Oxiranecarboxamide, N-(2-hydroxyphenyl)-3-phenyl-, (2R,3S)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Oxiranecarboxamide, N-(2-hydroxyphenyl)-3-phenyl-, (2R,3S)- (9CI)(680231-46-3)
• EPA Substance Registry System: Oxiranecarboxamide, N-(2-hydroxyphenyl)-3-phenyl-, (2R,3S)- (9CI)(680231-46-3)

Safety Data

• Hazardous Substances Data: 680231-46-3(Hazardous Substances Data)

Upstream product

• 95-55-6 2-amino-phenol 

Downstream Products

• 893421-97-1 (6S,7S)-7-hydroxy-6-phenyl-6,7-dihydro-9H-5-oxa-9-aza-benzocyclohepten-8-one 

Relevant articles and documents

CHEMICAL COMPOUNDS

The invention provides a new method for treating disorders associated with activation of the Notch signal transduction pathway comprising administering an effective amount of a compound of Formula (I), in free form or in a pharmaceutically acceptable salt

NOVEL MOLECULAR PROBES

The present invention relates to novel molecular probes having the formula (I) (I) useful for the characterization, detection, localization and isolation of the γ-secretase enzyme.

NOVEL LACTAMS AND USES THEREOF

Compounds having the formula (I) pharmaceutical compositions containing them and their methods of use for the treatment of neurological disorders related to amyloid ? protein production and neurological disorders such as Alzheimer's disease.. These compounds inhibit γ secretase and thereby inhibit the production of amyloid ? protein, thereby acting to prevent the formation of neurological deposits of amyloid protein.