cas 681001-30-9, (R)-8-HYDROXY-3-METHYL-1,2,3,4-TETRAHYDROBENZ[A]ANTHRACENE-7,12-DIONE

Articles about 681001-30-9Total 3 be found

Angucyclinone antibiotics: Total syntheses of YM-181741, (+)-ochromycinone, (+)-rubiginone B2, (-)-tetrangomycin, and MM-47755
(Chemical Equation Presented) A concise and highly enantioselective route has been developed for the synthesis of angucyclinone-type natural products. Utilizing this strategy, total syntheses of five natural products YM-181741, (+)-ochromycinone, (+)-rubi
Kaliappan, Krishna P.,Ravikumar, Velayutham
p. 6116 - 6126
(2008/02/10)

A facile synthesis of the angucyclinone antibiotic (+)-rubiginone B 2 involving the BF3-mediated Diels-Alder reaction of juglone
A short synthesis of (+)-rubiginone B2 is reported. The BF 3-mediated Diels-Alder reaction of juglone and (R)-3-methyl-1- vinylcyclohexene followed by aromatization gave the anthraquinone as the desired regioisomer, which was converted into the target antibiotic after a two-step operation.
Motoyoshiya, Jiro,Masue, Yusuke,Iwayama, Gento,Yoshioka, Sachiko,Nishii, Yoshinori,Aoyama, Hiromu
p. 2099 - 2102
(2007/10/03)

Total synthesis of Angucyclines. Part 18: A short and efficient synthesis of (+)-ochromycinone
A short and highly enantiospecific (seven steps, 99% ee) synthesis of (+)-ochromycinone 2 in 19% overall yield is reported. Key steps are the regioselective Diels-Alder reaction of the juglone derivative 4 with the mixture of dienes 5 and 9 derived from 3-methylcyclohexanone (99% ee) and the photooxidation of 1-deoxyochromycinone 3 to the natural ketone 2. A pronounced concentration dependence of the specific rotation was observed for (+)-ochromycinone 2 in CHCl3.
Krohn, Karsten,Sohrab, Md. Hossain,Floerke, Ulrich
p. 713 - 718
(2007/10/03)