682352-76-7

Basic information

• Product Name: 4-Isoxazolecarboxylicacid,3-(4-chlorophenyl)-5-formyl-,methylester(9CI)
• Synonyms: 4-Isoxazolecarboxylicacid,3-(4-chlorophenyl)-5-formyl-,methylester(9CI);Methyl 3-(4-chlorophenyl)-5-forMylisoxazole-4-carboxylate;3-(4-Chlorophenyl)-5-formyl-4-isoxazolecarboxylic acid methyl ester;3-(4-chlorophenyl)-5-formyl-4-Isoxazole carbocylic acid methyl ester
• CAS NO: 682352-76-7
• Molecular Formula: C₁₂H₈ClNO₄
• Molecular Weight: 265.65
• Product Categories: ISOXAZOLE
• Mol File: 682352-76-7.mol

Chemical Properties

• Boiling Point: 480.085°C at 760 mmHg (Cal.) ref.
• Flash Point: 244.147°C (Cal.) ref.
• Appearance: /
• Density: 1.382g/cm3 (Cal.) ref.
• PKA: -7.01±0.50(Predicted)
• CAS DataBase Reference: 4-Isoxazolecarboxylicacid,3-(4-chlorophenyl)-5-formyl-,methylester(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Isoxazolecarboxylicacid,3-(4-chlorophenyl)-5-formyl-,methylester(9CI)(682352-76-7)
• EPA Substance Registry System: 4-Isoxazolecarboxylicacid,3-(4-chlorophenyl)-5-formyl-,methylester(9CI)(682352-76-7)

Safety Data

• Hazardous Substances Data: 682352-76-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
4-Isoxazolecarboxylic acid, 3-(4-chlorophenyl)-5-formyl-, methyl ester (9CI) is used as a building block for the synthesis of various drugs and drug intermediates. Its unique chemical structure allows it to be a versatile component in the development of new pharmaceutical compounds.
Used in Antifungal Applications:
4-Isoxazolecarboxylic acid, 3-(4-chlorophenyl)-5-formyl-, methyl ester (9CI) is known for its potential antifungal activities. It can be used as an active ingredient in the development of antifungal medications, targeting a wide range of fungal infections.
Used in Antibacterial Applications:
4-Isoxazolecarboxylicacid,3-(4-chlorophenyl)-5-formyl-,methylester(9CI) also exhibits potential antibacterial activities, making it a candidate for use in the development of antibacterial drugs. It can be utilized to combat various bacterial infections and contribute to the treatment of infectious diseases.
It is important to handle and store 4-Isoxazolecarboxylic acid, 3-(4-chlorophenyl)-5-formyl-, methyl ester (9CI) with care, as it may pose a risk to human health and the environment if not properly managed.

Upstream product

• 682352-73-4 3-(4-chloro-phenyl)-5-hydroxymethyl-isoxazole-4-carboxylic acid methyl ester 
• 682352-84-7 3-(4-chloro-phenyl)-5-(hydroxyimino-methyl)-isoxazole-4-carboxylic acid methyl ester 
• 68870-58-6 methyl 3-(p-chlorophenyl)-5-methylisoxazole-4-carboxylate 
• 682352-69-8 3-(4-chloro-phenyl)-5-dibromomethyl-isoxazole-4-carboxylic acid methyl ester 

Downstream Products

• 811446-70-5 5-(1-acetoxy-2-butoxycarbonyl-allyl)-3-(4-chloro-phenyl)-isoxazole-4-carboxylic acid methyl ester 
• 811446-67-0 5-(1-acetoxy-2-methoxycarbonyl-allyl)-3-(4-chloro-phenyl)-isoxazole-4-carboxylic acid methyl ester 
• 811446-56-7 3-(4-chloro-phenyl)-5-(1-hydroxy-2-methoxycarbonyl-allyl)-isoxazole-4-carboxylic acid methyl ester 

Relevant articles and documents

Insights into the bromination of 3-aryl-5-methyl-isoxazole-4-carboxylate: Synthesis of 3-aryl-5-bromomethyl-isoxazole-4-carboxylate as precursor to 3-aryl-5-formyl-isoxazole-4-carboxylate

Results of the detailed investigations on the bromination of the methyl group of 3-aryl-5-methyl-isoxazole-4-carboxylate, a precursor to obtain 3-aryl-5-formyl-isoxazole-4-carboxylate, are described. The products generated during the study have been utilized as substrates for the synthesis of isoxazole-fused heterocycles.