68870-58-6

Basic information

• Product Name: 4-Isoxazolecarboxylic acid, 3-(4-chlorophenyl)-5-Methyl-, Methyl
• Synonyms: 4-Isoxazolecarboxylic acid, 3-(4-chlorophenyl)-5-Methyl-, Methyl;4-Isoxazolecarboxylic acid, 3-(4-chlorophenyl)-5-Methyl-, Methyl ester;Methyl 3-(4-chlorophenyl)-5-methylisoxazole-4-carboxylate
• CAS NO: 68870-58-6
• Molecular Formula: C₁₂H₁₀ClNO₃
• Molecular Weight: 251.6657
• Mol File: 68870-58-6.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-Isoxazolecarboxylic acid, 3-(4-chlorophenyl)-5-Methyl-, Methyl(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Isoxazolecarboxylic acid, 3-(4-chlorophenyl)-5-Methyl-, Methyl(68870-58-6)
• EPA Substance Registry System: 4-Isoxazolecarboxylic acid, 3-(4-chlorophenyl)-5-Methyl-, Methyl(68870-58-6)

Safety Data

• Hazardous Substances Data: 68870-58-6(Hazardous Substances Data)

Upstream product

• 4916-22-7 methyl 3-phenylaminobut-2-enoate 
• 28123-63-9 4-chlorobenzohydroximoyl chloride 
• 72002-24-5 methyl 3-(benzylamino)but-2-enoate 
• 36244-62-9 C₉H₁₇NO₂ 
• 73967-70-1 methyl 3-(isopropylamino)but-2-enoate 
• 13412-12-9 3-methylaminobut-2-enoic acid methyl ester 
• 34284-28-1 methyl acetoacetate, monosodium salt 
• 3848-36-0 4-chlorobenzaldoxime 
• 105-45-3 acetoacetic acid methyl ester 
• 18913-35-4 methyl buta-2,3-dienoate 

Downstream Products

• 91059-01-7 3-(4-chloro-phenyl)-5-methyl-isoxazole-4-carbonyl chloride 
• 91063-34-2 3-(4-chloro-phenyl)-5-methyl-isoxazole-4-carboxylic acid amide 
• 21106-64-9 6β-[3-(4-chloro-phenyl)-5-methyl-isoxazole-4-carbonylamino]-penicillanic acid 
• 95514-45-7 (E)-3-(p-chlorophenyl)-5-<2-(p-chlorophenyl)vinyl>isothiazole 
• 95514-46-8 (Z)-3-(p-chlorophenyl)-5-<2-(p-chlorophenyl)vinyl>isothiazole 
• 95514-34-4 (Z)-2-[3-(4-Chloro-phenyl)-isothiazol-5-yl]-1-(2,6-dichloro-phenyl)-vinylamine 
• 95514-35-5 (Z)-1-(4-Chloro-phenyl)-2-[3-(2,6-dichloro-phenyl)-isothiazol-5-yl]-vinylamine 
• 95514-37-7 3-(p-chlorophenyl)-5-(p-chlorophenacyl)isothiazole 
• 95514-30-0 (Z)-2-[3-(4-Chloro-phenyl)-isothiazol-5-yl]-1-(4-fluoro-phenyl)-vinylamine 
• 95514-31-1 (Z)-1-(4-Chloro-phenyl)-2-[3-(4-fluoro-phenyl)-isothiazol-5-yl]-vinylamine 
• 95514-22-0 1-amino-1-(p-chlorophenyl)-3-oxo-1-buten-2-carboxylic acid 
• 95514-39-9 3-(p-chlorophenyl)-5-<(trimethylsilyl)methyl>isothiazole 
• 95514-23-1 1-amino-1-(p-chlorophenyl)-1-buten-3-one 
• 95514-43-5 3-(p-chlorophenyl)-5-<2-<(tert-butyldimethylsilyl)amino>-2-(3,5-dichlorophenyl)vinyl>isothiazole 

Relevant articles and documents

Catalyst- and solvent-free mechanochemical synthesis of isoxazoles from N-hydroxybenzimidoyl chlorides and enamino carbonyl compounds

A regioselective, solvent-free and catalyst-free synthesis of isoxazoles has been successfully developed under ball milling conditions. Milling the mixtures of N-hydroxybenzimidoyl chlorides and enamino carbonyl compounds in a ball mill at a frequency of

Ring Transformation Equilibrium (Bond Switch) in the 5-(2-Aminovinyl)isothiazole System via Hypervalent Sulfurane. Synthesis, Structure Determination, and Kinetic Study

Reaction of 3-aryl-5-methylisothiazoles (4) with aromatic nitriles afforded the adducts 3, 5-(2-amino-2-arylvinyl)-3-arylisothiazole derivatives, in the presence of LDA.By employing p-chlorobenzonitrile-15N, the presence of ring transformation from one is