DNA binding ligands targeting drug-resistant Gram-positive bacteria. Part 2: C-terminal benzimidazoles and derivatives
The synthesis and in vitro potency of DNA minor-groove binding antibacterials lacking the C-terminal amide bond are described. The crescent shaped molecules bear the positively charged amino group at an internal pyrrole unit instead of the C-terminus. Thr
Buerli, Roland W.,Jones, Peter,McMinn, Dustin,Le, Quan,Duan, Jian-Xin,Kaizerman, Jacob A.,Difuntorum, Stacey,Moser, Heinz E.
p. 1259 - 1263
(2007/10/03)
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