683241-04-5

Basic information

• Product Name: Piperazine, 1-(3,5-difluoro-2-pyridinyl)- (9CI)
• Synonyms: Piperazine, 1-(3,5-difluoro-2-pyridinyl)- (9CI)
• CAS NO: 683241-04-5
• Molecular Formula: C9H11F2N3
• Molecular Weight: 199.2005464
• Product Categories: PYRIDINE
• Mol File: 683241-04-5.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Piperazine, 1-(3,5-difluoro-2-pyridinyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Piperazine, 1-(3,5-difluoro-2-pyridinyl)- (9CI)(683241-04-5)
• EPA Substance Registry System: Piperazine, 1-(3,5-difluoro-2-pyridinyl)- (9CI)(683241-04-5)

Safety Data

• Hazardous Substances Data: 683241-04-5(Hazardous Substances Data)

Upstream product

• 2875-18-5 2,3,5,6-tetrafluoropyridine 
• 668484-18-2 tert-butyl 4-(3,5,6-trifluoropyridin-2-yl)piperazine-1-carboxylate 
• 683241-03-4 tert-butyl 4-(3,5-difluoropyridin-2-yl)piperazine-1-carboxylate 

Relevant articles and documents

INHIBITORS OF DIHYDROCERAMIDE DESATURASE FOR TREATING DISEASE

Disclosed herein are dihydroceramide desaturase 1 (Des1) inhibitor compounds and compositions, which are useful in the treatment of diseases, such as metabolic disorders, where inhibition of Des1 is expected to be therapeutic to a patient. Methods of inhibition of Des1 activity in a human or animal subject are also provided.

BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS VANILLOID RECEPTOR LIGANDS

Compounds of formula (I) are useful in the treatment of vanilloid-receptor-meditated diseases, such as inflammatory or neuropathic pain and diseases involving sensory nerve function such as asthma, rheumatoid arthritis, osteoarthritis, inflammatory bowel disorders, urinary incontinence, migraine and psoriasis.