684250-21-3

Basic information

• Product Name: 2,4-Difluoro-6-((triMethylsilyl)ethynyl)aniline
• Synonyms: 2,4-Difluoro-6-((triMethylsilyl)ethynyl)aniline
• CAS NO: 684250-21-3
• Molecular Formula: C₁₁H₁₃F₂NSi
• Molecular Weight: 225.3099264
• Mol File: 684250-21-3.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2,4-Difluoro-6-((triMethylsilyl)ethynyl)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Difluoro-6-((triMethylsilyl)ethynyl)aniline(684250-21-3)
• EPA Substance Registry System: 2,4-Difluoro-6-((triMethylsilyl)ethynyl)aniline(684250-21-3)

Safety Data

• Hazardous Substances Data: 684250-21-3(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
2,4-Difluoro-6-((triMethylsilyl)ethynyl)aniline is used as a reagent in organic synthesis for the construction of complex molecules. Its unique structure allows for the creation of intricate chemical entities that are otherwise difficult to synthesize.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2,4-Difluoro-6-((triMethylsilyl)ethynyl)aniline is used as a building block for the development of new drugs. Its specific chemical properties contribute to the design and synthesis of potential therapeutic agents.
Used in Agrochemical Industry:
2,4-Difluoro-6-((triMethylsilyl)ethynyl)aniline is also utilized in the agrochemical sector, serving as a component in the synthesis of new pesticides or other agricultural chemicals, enhancing crop protection and yield.
Used in Materials Science:
In the field of materials science, 2,4-Difluoro-6-((triMethylsilyl)ethynyl)aniline is used as a precursor for the synthesis of novel organic electronic materials. Its properties are harnessed to develop advanced materials for use in electronic devices and components.
Used in Polymer Preparation:
2,4-Difluoro-6-((triMethylsilyl)ethynyl)aniline is used in the preparation of functional polymers, where its unique reactivity and structure contribute to the creation of polymers with specific properties for various applications.
Overall, 2,4-Difluoro-6-((triMethylsilyl)ethynyl)aniline's applications span across multiple industries, highlighting its importance in the development of new technologies and products in chemistry, medicine, and materials science.

Upstream product

• 444-14-4 2-bromo-4,6-difluoroaniline 
• 1066-54-2 trimethylsilylacetylene 
• 367-25-9 2,4-difluorophenylamine 
• 582319-15-1 2,4-difluoro-6-iodo-aniline 

Relevant articles and documents

Polycyclic compound and preparation method and application thereof

The invention discloses a polycyclic compound and a preparation method and application thereof. The invention provides a polycyclic compound shown as a formula I or a pharmaceutically acceptable saltthereof. The compound has a relatively good inhibition effect on CDK7.

P -Toluenesulfonic Acid Induced Conversion of Fluorinated Trimethylsilylethynylanilines into Aminoacetophenones: Versatile Precursors for the Synthesis of Benzoazaheterocycles

A simple and efficient approach to the synthesis of fluorinated amino-substituted acetophenones in good to excellent yields is reported. The heart of the proposed method consists of conversion of a Me 3 Si-C≡C- moiety into a MeC(=O)- group in the presence of p -tolu ene sulfonic acid (p -TSA) passing a stage of ethynylaniline formation. The reaction is metal-free, proceeds under mild conditions, and uses readily available starting compounds (trimethylsilylarylacetylene derivatives). The reaction provides access to amino-substituted acetophenones, which may serve as precursors for the synthesis of polyfluorinated azaheterocycles, having potential anticarcinogenic activity.

CuI-Catalyzed intramolecular aminocyanation of terminal alkynes in N-(2-ethynylphenyl)-N-sulfonylcyanamides via Cu-vinylidene intermediates

CuI-Catalyzed intramolecular aminocyanation of terminal alkynes in N-(2-ethynylphenyl)-N-sulfonylcyanamides was initiated by the formation of Cu-acetylide to trigger N-CN bond cleavage of the N-sulfonylcyanamide moiety followed by CN migration to form a β-cyano Cu-vinylidene intermediate. Subsequently, the indole ring closure furnished the corresponding 1-sulfonyl-3-cyanoindoles.

4-AMINO-6-(HETEROCYCLIC)PICOLINATES AND 6-amino-2-(HETEROCYCLIC)pyrimidine-4-carboxylates AND THEIR USE AS HERBICIDES

4-Amino-6-(heterocyclic)picolinic acids and their derivatives; 6-amino-2-(heterocyclic)pyrimidine-4-carboxylates and their derivatives; and methods of using the same as herbicides.

Gold(III)-catalyzed annulation of 2-alkynylanilines: A mild and efficient synthesis of indoles and 3-haloindoles

Gold(III)-catalyzed annulation of 2-alkynylanilines in EtOH or EtOH-water mixtures at room temperature gives indoles derivatives in good yields. One-flask protocol for the gold-catalyzed conversion of 2-alkynylanilines to 3-bromo and 3-iodoindoles is also reported.