582319-15-1

Basic information

• Product Name: 2,4-DIFLUORO-6-IODOANILINE
• Synonyms: 2,4-DIFLUORO-6-IODOANILINE;2-Amino-3,5-difluoroiodobenzene;2,4-Difluoro-6-iodobenzenamine
• CAS NO: 582319-15-1
• Molecular Formula: C₆H₄F₂IN
• Molecular Weight: 255
• Mol File: 582319-15-1.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 231℃
• Flash Point: 93℃
• Appearance: /
• Density: 2.086
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 1.20±0.10(Predicted)
• CAS DataBase Reference: 2,4-DIFLUORO-6-IODOANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-DIFLUORO-6-IODOANILINE(582319-15-1)
• EPA Substance Registry System: 2,4-DIFLUORO-6-IODOANILINE(582319-15-1)

Safety Data

• Hazard Codes: T
• Hazardous Substances Data: 582319-15-1(Hazardous Substances Data)

Usage

General Description

2,4-Difluoro-6-iodoaniline is a chemical compound with the molecular formula C6H4F2IN. It is a derivative of aniline, consisting of a benzene ring with two fluorine atoms and one iodine atom attached to it. 2,4-Difluoro-6-iodoaniline is commonly used in organic synthesis and pharmaceutical research, as it can be utilized as a building block for the synthesis of various pharmaceuticals and agrochemicals. It is important to handle this chemical with caution, as it can be harmful if ingested, inhaled, or absorbed through the skin. Additionally, it may cause irritation to the eyes, skin, and respiratory system. Proper safety measures and protective equipment should be used when working with 2,4-Difluoro-6-iodoaniline.

InChI:InChI=1S/C6H4F2IN/c7-3-1-4(8)6(10)5(9)2-3/h1-2H,10H2

Upstream product

• 367-25-9 2,4-difluorophenylamine 

Downstream Products

• 684250-12-2 2-ethynyl-4,6-difluoroaniline 
• 1363411-85-1 C₁₄H₁₅F₂NO₂ 
• 1363411-84-0 C₁₄H₉F₂N 
• 1363411-83-9 C₁₂H₁₃F₂N 
• 1363411-82-8 C₁₁H₁₁F₂NO 
• 684250-21-3 2,4-difluoro-6-[(trimethylsilyl)ethynyl]aniline 
• 1297280-41-1 2-(3-((1-(2,4-difluorobenzyl)-6-oxo-1,6-dihydropyridazin-3-yl)methyl)-5,7-difluoro-2-methyl-1H-indol-1-yl)acetic acid 
• 1297280-23-9 2-(3-(1-benzyl-6-oxo-1,6-dihydropyridazin-3-yl)-5,7-difluoro-2-methyl-1H-indol-1-yl)acetic acid 

Relevant articles and documents

Polycyclic compound and preparation method and application thereof

The invention discloses a polycyclic compound and a preparation method and application thereof. The invention provides a polycyclic compound shown as a formula I or a pharmaceutically acceptable saltthereof. The compound has a relatively good inhibition effect on CDK7.

NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS

The present invention discloses compounds according to Formula (I), wherein R1, R3, R4, R5, L1, and Cy are as defined herein. The present invention also provides compounds, methods for the production of said compounds of the invention, pharmaceutical compositions comprising the same and their use in allergic or inflammatory conditions, autoimmune diseases, proliferative diseases, transplantation rejection, diseases involving impairment of cartilage turnover, congenital cartilage malformations, and/or diseases associated with hypersecretion of IL6 and/or interferons. The present invention also methods for the prevention and/or treatment of the aforementioned diseases by administering a compound of the invention.

Synthesis of polyfluorinated ortho-alkynylanilines

A series of polyfluorinated ortho-alkynylanilines - the versatile building blocks for diverse polyfluorobenzo azaheterocycles - have been synthesized by the Sonogashira reaction of polyfluorinated ortho-iodanilines with terminal alkynes.