Synthesis and Antiarrhythmic Activity of New 3--4-phenyl-3-buten-2-ones and Related Compounds
A number of the title compounds (1) and a few related hydroquinone derivatives (2) have been synthesized and tested for antiarrhythmic activity in vivo (protection against CaCl2-induced ventricular fibrillation in anesthetized rat) and in vitro (ability t
Salimbeni, Aldo,Manghisi, Elso,Fregnan, Giancarlo B.,Prada, Marco
p. 773 - 780
(2007/10/02)
RING OPENING AND RING-CHAIN TAUTERISM IN 2-CARBALKOXY- AND 2-ACYL-2,3-DIHYDRO-1,4-BENZODIOXINS.
The behaviour of benzodioxin esters 1a-c and ketones 2a-c under the action of K2CO3 in acetone and of NaH in DMSO has been studied; the experiments were also carried out in the presence of scavengers of phenolic intermediates or products.Under the action
Rosnati, Vittorio,Salimbeni, Aldo
p. 4541 - 4548
(2007/10/02)
Phenoxyalkylamines
The invention provides a new class of aminoalkoxyphenoxyalkenones having interesting pharmacological properties.
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(2008/06/13)
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