6942-01-4

Efficient oil–water separation plays a vital role in treating large amounts of industrial wastewater. However, current traditional separation methods are entwined with problems such as low efficiency and poor operability. Herein, we reported a nanofiber based on electrospinning and electrospray technology and spraying microspheres on the surface of a fiber mat for efficient oil–water separation. Owing to the electrostatic repulsion among the microspheres, the surface of the developed membrane had a honeycomb-like through-hole structure and super-high oil–water separation efficiency and oil flux. After 10 cycles, the membrane showed good separation efficiency and flux. This innovative work may provide a new idea and method for the design of biomimetic biopolymers, with broad application prospects in the field of oil–water separation.

The invention discloses epoxy resin with a long alkyl side chain as well as a preparation method and a curing method thereof, and belongs to the technical field of epoxy resin toughening. The structural formula of the epoxy resin monomer with the long alk

Adjuvants are added to vaccines to enhance the immune response and provide increased protection against disease. In the last decade, hundreds of synthetic immune adjuvants have been created, but many induce undesirable levels of proinflammatory cytokines including TNF-α and IL-6. Here we present small molecule NF-κB inhibitors that can be used in combination with an immune adjuvant to both decrease markers associated with poor tolerability and improve the protective response of vaccination. Additionally, we synthesize a library of honokiol derivatives identifying several promising candidates for use in vaccine formulations.

The present invention provides a positive photosensitive resin composition containing (A) a polymer compound containing a siloxane chain, the polymer compound having a repeating unit shown by the general formula (1) and a weight average molecular weight of 3,000 to 500,000, (B) a photosensitive material capable of generating an acid by light and increasing a dissolution rate in an aqueous alkaline solution, (C) a crosslinking agent, and (D) a solvent. There can be provided a positive photosensitive resin composition that can remedy the problem of delamination caused on a metal wiring such as Cu and Al, an electrode, and a substrate, especially on a substrate such as SiN, and can form a fine pattern having a forward tapered shape without generating a scum and a footing profile in the pattern bottom and on the substrate when a widely used 2.38% TMAH aqueous solution is used as the developer.

The present invention provides a silicone skeleton-containing polymer compound containing a repeating unit shown by the general formula (1) and having a weight average molecular weight of 3,000 to 500,000. There can be provided a silicone skeleton-containing polymer compound suitable used as a base resin of a chemically amplified negative resist composition that can remedy the problem of delamination generated on a metal wiring such as Cu and Al, an electrode, and a substrate, especially on a substrate such as SiN, and can form a fine pattern without generating a scum and a footing profile in the pattern bottom and on the substrate when the widely used 2.38% TMAH aqueous solution is used as a developer.

A small collection of C2-symmetry hydroxylated biphenyls was prepared by straightforward methods and the capability to act as inhibitors of tyrosinase has been evaluated by both spectrophotometric and electrochemical assays. Our attention was f

A group of 36 biphenyl derivatives structurally related to honokiol were synthesized by means of Suzuki coupling reactions. Their cytotoxicities were evaluated and compared to that of honokiol. Some of the compounds were then evaluated for their ability to downregulate the secretion of the VEGF protein and the expression of the VEGF, hTERT, and c-Myc genes; the two latter involved in the activation of telomerase in tumoral cells. Some of the synthetized derivatives showed promising pharmacological features as they exhibited IC50 values in low micromolar range, good therapeutic margins, and a multiple mode of action on tumor cells based on the inhibition of VEGF and, at the same time, of the expression of genes related to the activation of telomerase.

The present invention relates to an epoxy compound having an alkoxysilylalkyl-S-alkyl group and a method for preparing the same, and a composite of organic-inorganic materials comprising a cured product thereof and a method for preparing the composite. Th

There is provided a composition including an alkoxysilylated epoxy compound, a composition of which exhibits good heat resistance properties, low CTE and high glass transition temperature or Tg-less and not requiring a separate coupling agent, and inorganic particles, a cured product formed of the composition, and a use of the cured product. An epoxy composition including an alkoxysilylated epoxy compound and inorganic particles, an epoxy composition including an epoxy compound, inorganic particles and a curing agent, a cured product of the composition, and a use of the composition are provided. Since chemical bonds may be formed between the alkoxysilyl group and the inorganic particles and between the alkoxysilyl groups, a composition of the composition including the alkoxysilylated epoxy compound and the inorganic particles exhibits improved heat resistance properties, decreased CTE, and increased glass transition temperature or Tg less.

Provided are an alkoxysilylated epoxy compound, a composite of which exhibits good heat resistance properties, particularly low CTE and increased glass transition temperature, and a cured product thereof exhibits good flame retardancy and composition of w

The present invention relates to an alkoxysilyl-based epoxy compound which exhibits excellent heat resistance characteristics, more particularly, a low coefficient of thermal expansion (CTE) and a high glass transition temperature in a composite, and/or which exhibits excellent flame retardancy in a cured product, and which eliminates the necessity of a separate silane coupling agent. The present invention also relates to a method for preparing the compound, and to a composition and cured product comprising the compound. According to the present invention, provided are: an alkoxysilyl-based epoxy compound having at least one alkoxysilyl group and at least two epoxy groups; a method for preparing the alkoxysilyl-based epoxy compound by means of the ring-opening of the epoxy of a starting material and alkoxysilylation; an epoxy composition comprising the epoxy compound; and a cured product made therefrom and the use thereof. The efficiency of the chemical bonding of the cured product, which is a composite of the composition comprising a novel alkoxysilyl-based epoxy compound according to the present invention, is improved when a composite is formed not only by chemical bonding between an alkoxysilyl group of the epoxy compound and a filler, but also by chemical bonding between alkoxysilyl groups of the epoxy compound having the alkoxysilyl groups. Accordingly, the compound of the present invention exhibits excellent heat resistance characteristics, such as a low CTE and a high glass transition temperature in a composite, and/or exhibits excellent flame retardancy in a cured product.

Disclosed are an epoxy compound having an alkoxysilyl group, a composite of which exhibits good heat resistant properties and/or a cured product of which exhibits good flame retardant properties, a method of preparing the same, a composition comprising the same, and a cured product and a use of the composition. An alkoxysilylated epoxy compound comprising at least one of Chemical Formula S1 substituent and at least two epoxy groups in a core, a method of preparing the epoxy compound by an allylation, a claisen rearrangement, an epoxidation and an alkoxysilylation, an epoxy composition comprising the epoxy compound, and a cured product and a use of the composition are provided. The composite of the disclosed exhibits improved chemical bonding, good heat resistant properties, a low CTE, a high glass transition temperature or Tg-less The cured product of the composition exhibits good flame retardant properties.

Disclosed are an epoxy compound having an alkoxysilyl group, a composite of which exhibits good heat resistant properties and/or a cured product of which exhibits good flame retardant properties, a method of preparing the same, a composition comprising the same, a cured product of the composition and a use of the composition. An alkoxysilylated epoxy compound comprising at least one of Chemical Formula S1 substituent and at least two epoxy groups in a core, a method of preparing the epoxy compound by an allylation, a claisen rearrangement, a glycidylation and an alkoxysilylation, an epoxy composition comprising the epoxy compound, a cured product of the composition and a use of the composition are provided. The composite of the composition comprising the alkoxysilylated epoxy compound exhibits improved chemical bonding,-good heat resistant properties, a low CTE, a high glass transition temperature or Tg-less via the enhanced chemical bonding efficiency of alkoxysilyl group. The cured product of the composition exhibits good flame retardant properties.

A facile synthetic route of the tandem Claisen rearrangement/aerobic Wacker-type oxidative cyclization toward 5,5′-bis-benzofurans 2 and 5-arylbenzofurans 3 starting with bis-allyl aryl ethers 4 or allyl aryl ethers 5 with good yields is described. Skelet

A straightforward synthesis of 3,8-dimethoxy-10,11-dihydrobenzo[j] fluoranthen-12-ones 1 is reported in a seven-step route from biphenyl-4,4′-diol 2 via the transformation of a double Claisen rearrangement, cross metathesis with ethyl acrylate, and polyph

A silylated dihydroxy aromatic compound of the formula (1a); wherein Ga and Gb are each independently C1-12 alkyl, —OSi(C1-12 alkyl)3, C1-12 arylalkyl, or —OSi(C1-12 arylalkyl)s

A series of new bisphenol derivatives bearing allylic moieties were synthesized as potential analogs of honokiol and/or magnolol. Certain compounds exhibited specific anti-proliferation activity against SVR cells and moderate anti-HIV-1 activity in primary human lymphocytes. Compound 5h was the most potent compound and its anti-tumor activity was evaluated in vivo.

A synthetic strategy based on tandem application of double Claisen rearrangement and two-directional ring-closing metathesis reaction as key-steps has been developed for the synthesis of various hitherto unknown tri-, tetra- and pentacyclic benzofused bis

A novel monomer composition is described. The novel monomer composition includes at least one property imparting unit. The property imparting unit has at least one member selected from the group consisting of conductivity imparting unit, stability imparting unit and any combinations thereof. The novel monomer may further include a delinking agent, which is attached to at least one of said property imparting unit. The delinking agent includes at least one member selected from the group consisting of C—C bond, CH2, CH3, CF2, CF3, Si, O, S, functional groups, aromatic residues and any combinations thereof.

In a successful attempt to amplify the pharmacological activity of the antimalarial bialamicol, substituents have been introduced in the 2-position of the allyl side chains. 2-Fluoroallyl bromide, a versatile C3F building block, is described for the first time.

Analogs of 5,5'-di-2-propenyl-3,3'-bis(1-pyrrolidinylmethyl) [1,1'-biphenyl]-4,4'-diol 2 which exhibited modest activity against chloroquine- and mefloquine-resistant lines of Plasmodium berghei were prepared. Modifications of the Mannich side chain, the propenyl group, and analogs wherein a bridging atom was inserted between the phenyl rings were prepared. None of the structural changes provided an improvement in antimalarial activity over the lead compound in the P. berghei mouse system.