Phase transfer catalysis extends the scope of the Algar-Flynn-Oyamada synthesis of 3-Hydroxyflavones
The Algar-Flynn-Oyamada reaction is the classical method to synthesize 3-hydroxyflavones from chalcones. Despite its relative simplicity, the reaction has several drawbacks including variable and often low product yields. We have found that phase transfer
Nhu, Duong,Hawkins, Bill C.,Burns, Christopher J.
p. 1102 - 1107
(2016/01/15)
Solution phase synthesis of a combinatorial library of chalcones and flavones as potent cathepsin v inhibitors
Cathepsin V is a papain-like cysteine protease. It is involved in the control of human T cells (responsible for cell immunity), and presents the largest elastolytic activity among the proteolytic enzymes. Therefore, cathepsin V is a potential molecular ta
Alvim, Joel,Severino, Richele P.,Marques, Emerson F.,Martinelli, Ariane M.,Vieira, Paulo C.,Fernandes, Joao B.,Da Silva, M. Fatima Das G. F.,Correa, Arlene G.
experimental part
p. 687 - 695
(2010/11/18)
STRUCTURAL CONFIRMATION OF SPIROELLIPTIN FROM IRYANTHERA ELLIPTICA BY SYNTHESIS
Spiroelliptin, a spiro from Iryanthera elliptica was synthesized by a novel process which involved the catalytic hydrogenation of the appropriate chalcone.This and other spiro derivati
Morais, Anselmo A.,Fo, Raimundo Braz,Gottlieb, Otto R.
p. 3023 - 3028
(2007/10/02)
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