70239-64-4Relevant academic research and scientific papers
Phase transfer catalysis extends the scope of the Algar-Flynn-Oyamada synthesis of 3-Hydroxyflavones
Nhu, Duong,Hawkins, Bill C.,Burns, Christopher J.
, p. 1102 - 1107 (2016/01/15)
The Algar-Flynn-Oyamada reaction is the classical method to synthesize 3-hydroxyflavones from chalcones. Despite its relative simplicity, the reaction has several drawbacks including variable and often low product yields. We have found that phase transfer
Solution phase synthesis of a combinatorial library of chalcones and flavones as potent cathepsin v inhibitors
Alvim, Joel,Severino, Richele P.,Marques, Emerson F.,Martinelli, Ariane M.,Vieira, Paulo C.,Fernandes, Joao B.,Da Silva, M. Fatima Das G. F.,Correa, Arlene G.
experimental part, p. 687 - 695 (2010/11/18)
Cathepsin V is a papain-like cysteine protease. It is involved in the control of human T cells (responsible for cell immunity), and presents the largest elastolytic activity among the proteolytic enzymes. Therefore, cathepsin V is a potential molecular ta
STRUCTURAL CONFIRMATION OF SPIROELLIPTIN FROM IRYANTHERA ELLIPTICA BY SYNTHESIS
Morais, Anselmo A.,Fo, Raimundo Braz,Gottlieb, Otto R.
, p. 3023 - 3028 (2007/10/02)
Spiroelliptin, a spiro from Iryanthera elliptica was synthesized by a novel process which involved the catalytic hydrogenation of the appropriate chalcone.This and other spiro derivati
