Anti-Lung Cancer Activities of 1,2,3-Triazole Curcumin Derivatives via Regulation of the MAPK/NF-κB/STAT3 Signaling Pathways
In this study, a series of curcumin derivatives containing 1,2,3-triazole were designed and synthesized, and their inhibitory activities against the proliferation of lung cancer cells were studied. Compound 5 k (3,4-dichlorobenzyltriazole methyl curcumin)
Zhi, Tai Xin,Liu, Kai Qiang,Cai, Kun Yi,Zhao, Yu Chao,Li, Zhen Wang,Wang, Xin,He, Xin Hua,Sun, Xian Yu
(2021/12/01)
Tris-isocyanide copper(I) complex enabling copper azide-alkyne cycloaddition in neat conditions
The three-coordinated homoleptic Cu(I) complex with 2,6-dimethylphenyl isocyanide in the coordination sphere was easily synthesized and isolated as tetrafluoroborate salt. The structure of the compound was determined by single-crystal X-ray diffraction. T
An abnormal N-heterocyclic carbene-copper(I) complex in click chemistry
Herein we report the synthesis of a copper(I) chloro complex using an abnormal N-heterocyclic carbene (aNHC) salt, 1,3-bis(2,6-diisopropylphenyl)-2,4- diphenylimidazolium. The Cu(aNHC) complex efficiently catalyzed Huisgen 1,3-dipolar cycloaddition reacti
Sau, Samaresh Chandra,Roy, Sudipta Raha,Sen, Tamal K.,Mullangi, Dinesh,Mandal, Swadhin K.
p. 2982 - 2991
(2014/03/21)
Conventional and microwave assisted synthesis of 1,4-disubstituted 1,2,3-triazoles from Huisgen cycloaddition
In this paper the synthesis of a library of new 1,4-disubstituted 1,2,3-triazoles 1, with a variety of additional functional groups on its structure, from an in situ generated benzyl azide 2 and different alkynes and dialkynes 3 is reported. Optimal exper
Sarmiento-Sanchez, Juan I.,Ochoa-Teran, Adrian,Rivero, Ignacio A.
experimental part
p. 177 - 188
(2011/08/07)
PHARMACOLOGICALLY ACTIVE GUANIDINE COMPOUNDS
The compounds are substituted thioalkyl-, aminoalkyl-and oxyalkyl-guanidines which are inhibitors of histamine activity.
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(2008/06/13)
PHARMACOLOGICALLY ACTIVE THIOUREA AND UREA COMPOUNDS
The compounds are substituted thioalkyl-, aminoalkyl-and oxyalkyl-thioureas and ureas which are inhibitors of histamine activity.
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(2008/06/13)
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