70380-29-9

Usage

Uses

Used in Pharmaceutical Industry:
1-Benzyl-4-(chloromethyl)-1H-1,2,3-triazole is used as a building block for the synthesis of molecules with cytostatic activity. Its unique structure allows it to be incorporated into the design of new drugs that can potentially inhibit the growth and proliferation of cancer cells, making it a valuable component in the development of anticancer agents.

Upstream product

• 100-39-0 benzyl bromide 
• 28798-81-4 (1-benzyl-[1,2,3]triazol-4-yl)methanol 
• 622-79-7 benzyl azide 
• 624-65-7 2-propynyl chloride 

Downstream Products

• 1187396-71-9 (1-benzyl-1H-1,2,3-triazole-4-yl)acetonitrile 
• 258261-56-2 N-[1-[1-benzyl-1,2,3-(1H)-triazol-5-yl]-3-oxo-2-pentyl]propanamide 
• 128864-39-1 di-<(1-benzyl-1H-1,2,3-triazol-4-yl)-methylen>sulfide 
• 128864-40-4 1-benzyl-4-ethylthiomethylen-1H-1,2,3-triazole 

Relevant academic research and scientific papers

Anti-Lung Cancer Activities of 1,2,3-Triazole Curcumin Derivatives via Regulation of the MAPK/NF-κB/STAT3 Signaling Pathways

In this study, a series of curcumin derivatives containing 1,2,3-triazole were designed and synthesized, and their inhibitory activities against the proliferation of lung cancer cells were studied. Compound 5 k (3,4-dichlorobenzyltriazole methyl curcumin)

Tris-isocyanide copper(I) complex enabling copper azide-alkyne cycloaddition in neat conditions

The three-coordinated homoleptic Cu(I) complex with 2,6-dimethylphenyl isocyanide in the coordination sphere was easily synthesized and isolated as tetrafluoroborate salt. The structure of the compound was determined by single-crystal X-ray diffraction. T

An abnormal N-heterocyclic carbene-copper(I) complex in click chemistry

Herein we report the synthesis of a copper(I) chloro complex using an abnormal N-heterocyclic carbene (aNHC) salt, 1,3-bis(2,6-diisopropylphenyl)-2,4- diphenylimidazolium. The Cu(aNHC) complex efficiently catalyzed Huisgen 1,3-dipolar cycloaddition reacti

Conventional and microwave assisted synthesis of 1,4-disubstituted 1,2,3-triazoles from Huisgen cycloaddition

In this paper the synthesis of a library of new 1,4-disubstituted 1,2,3-triazoles 1, with a variety of additional functional groups on its structure, from an in situ generated benzyl azide 2 and different alkynes and dialkynes 3 is reported. Optimal exper

PHARMACOLOGICALLY ACTIVE GUANIDINE COMPOUNDS

The compounds are substituted thioalkyl-, aminoalkyl-and oxyalkyl-guanidines which are inhibitors of histamine activity.

PHARMACOLOGICALLY ACTIVE THIOUREA AND UREA COMPOUNDS

The compounds are substituted thioalkyl-, aminoalkyl-and oxyalkyl-thioureas and ureas which are inhibitors of histamine activity.