Quino[2,3:3,4]pyrrolo[2,1-b]quinazolin-11(13H)-one, 7,8,9-trimethoxy- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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Basic information
1. Product Name: Quino[2,3:3,4]pyrrolo[2,1-b]quinazolin-11(13H)-one, 7,8,9-trimethoxy-
2. Synonyms: Quino[2,3:3,4]pyrrolo[2,1-b]quinazolin-11(13H)-one, 7,8,9-trimethoxy-
3. CAS NO:704912-42-5
4. Molecular Formula: C21H17N3O4
5. Molecular Weight: 375.37738
6. EINECS: N/A
7. Product Categories: N/A
8. Mol File: 704912-42-5.mol
Chemical Properties
1. Melting Point: N/A
2. Boiling Point: N/A
3. Flash Point: N/A
4. Appearance: /
5. Density: N/A
6. Refractive Index: N/A
7. Storage Temp.: N/A
8. Solubility: N/A
9. CAS DataBase Reference: Quino[2,3:3,4]pyrrolo[2,1-b]quinazolin-11(13H)-one, 7,8,9-trimethoxy-(CAS DataBase Reference)
10. NIST Chemistry Reference: Quino[2,3:3,4]pyrrolo[2,1-b]quinazolin-11(13H)-one, 7,8,9-trimethoxy-(704912-42-5)
11. EPA Substance Registry System: Quino[2,3:3,4]pyrrolo[2,1-b]quinazolin-11(13H)-one, 7,8,9-trimethoxy-(704912-42-5)
Safety Data
1. Hazard Codes: N/A
2. Statements: N/A
3. Safety Statements: N/A
4. WGK Germany:
5. RTECS:
6. HazardClass: N/A
7. PackingGroup: N/A
8. Hazardous Substances Data: 704912-42-5(Hazardous Substances Data)

704912-42-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 704912-42-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,0,4,9,1 and 2 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 704912-42:
(8*7)+(7*0)+(6*4)+(5*9)+(4*1)+(3*2)+(2*4)+(1*2)=145
145 % 10 = 5
So 704912-42-5 is a valid CAS Registry Number.

704912-42-5Upstream product

704912-42-5Downstream Products

704912-42-5Relevant articles and documents

Synthesis and topoisomerase I inhibitory properties of luotonin A analogues

Cagir, Ali,Eisenhauer, Brian M.,Gao, Rong,Thomas, Shannon J.,Hecht, Sidney M.

, p. 6287 - 6299 (2007/10/03)

Luotonin A, a naturally occurring pyrroloquinazolinoquinoline alkaloid, has been previously demonstrated to be a topoisomerase I poison. A number of luotonin A derivatives have now been prepared through the condensation of anthranilic acid derivatives and 1,2-dihydropyrrolo[3,4-b]quinoline-3-one in the presence of phosphorus oxychloride. When dichloromethane was used as solvent the reaction proceeded to a single product. In contrast when the reaction was carried out in tetrahydrofuran or in phosphorus oxychloride, an additional isomeric product was obtained. The luotonin A analogues were evaluated for their ability to effect stabilization of the covalent binary complex formed between human topoisomerase I and DNA, and for cytotoxicity toward a yeast strain expressing the human topoisomerase I.

Synthesis and biochemical properties of E-ring modified luotonin a derivatives

Cagir, Ali,Jones, Shannon H.,Eisenhauer, Brian M.,Gao, Rong,Hecht, Sidney M.

, p. 2051 - 2054 (2007/10/03)

Luotonin A is a cytotoxic pyrroloquinazolinoquinoline alkaloid that has been shown to stabilize the human topoisomerase I-DNA covalent binary complex in the same fashion as the antitumor alkaloid camptothecin. A study of the structural elements in luotoni

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704912-42-5