- LIPOXYGENASE INHIBITORS
-
Various embodiments of the present disclosure are directed to compounds having Formula I, Formula II, Formula IIA, Formula III, Formula IIIA, Formula IIIB, and/or pharmaceutically acceptable salts thereof. The compounds can be suitable for inhibiting lipoxygenases and/or treating associated diseases. In some embodiments, subject compounds are used to prepare a composition that is effective in treating neurodegenerative diseases.
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Paragraph 00234; 00235
(2021/07/02)
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- LIPOXYGENASE INHIBITORS
-
Various embodiments of the present disclosure are directed to compounds having Formula (I), Formula (IA), Formula (IB), Formula (IC), Formula (ID), Formula (IE), and/or pharmaceutically acceptable salts thereof. The compounds can be suitable for inhibiting lipoxygenases, and/or treating associated diseases, such as Alzheimer's disease. In some embodiments, the compounds may be administered to a patient as part of a pharmaceutical formulation.
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Paragraph 00558-00561
(2021/10/02)
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- PHENYL-SULFAMOYL.BENZOYC ACIDS AS ERAP1 MODULATORS
-
The present invention relates to a compound of formula (I), or a pharmaceutically acceptable salt or hydrate thereof, wherein: the group X-Y is -NHSO2- or -SO2NH-; Z is a monocyclic aryl or heteroaryl group, each of which is optionally substituted by one ormore substituents selected from alkyl, cycloalkyl, halo, alkoxy, CN, haloalkyl and OH; R1 is H or alkyl; R2 is selected from COOH and a tetrazolyl group; R3 is selected from H, C land alkyl; R4 is selected from H and halo; R5 is selected from H, alkyl, haloalkyl, SO2-alkyl,Cl, alkoxy, OH, CN, hydroxyalkyl, alkylthio, heteroaryl, cycloalkyl, heterocycloalkyl andhaloalkoxy; R6 is H; R7 is selected from H, CN, haloalkyl, halo, SO2-alkyl,SO2NR12R13, heteroaryl, CONR10R11 and alkyl, wherein said heteroaryl group is optionallysubstituted by one or more substituents selected from alkyl, halo, alkoxy, CN, haloalkyl and OH; R8 is selected from H, alkyl, haloalkyl and halo; and R9 is H, alkyl or halo; R10 and R11 are each independently H or alkyl; and R12 and R13 are each independently H or alkyl. Further aspects of the invention relate to such compounds for use in the field of immuno- oncology and related applications. Another aspect of the invention relates to compounds of formulae (la) and (lb).
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Page/Page column 242
(2020/11/23)
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- A compound. Hole transporting material, organic electroluminescent device and display device (by machine translation)
-
The invention provides a compound of general formula (I). It can be used for hole transport materials. The compound has the fluorene fused ring-linked ortho-substituted phenyl triarylamine parent structure, the bond between atoms can be high, good thermal stability is achieved, solid deposition between molecules is facilitated, and the transition capability of holes is high. Be applied to hole transport layer, have suitable energy level level between adjacent level, be favorable to the injection and the migration of hole, can effectively reduce drive voltage, higher hole mobility simultaneously, can effectively promote organic electroluminescence device's luminous efficiency. The invention also provides a hole transport material comprising the compound of the general formula (I). Organic electroluminescent device and display device. (by machine translation)
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Paragraph 0116-0117; 0121
(2021/01/04)
-
- Copper(II)-Catalyzed Iodinations of Carbazoles: Access to Functionalized Carbazoles
-
A copper-catalyzed iodination of carbazoles has been developed. Barluenga's reagent IPy2BF4 is used to generate a soft electrophilic halonium species for the iodination of the carbazoles. This report represents the first concept of copper-catalyst-promoted electrophilic halogenation of carbazoles. We demonstrated numerous applications of this methodology synthesizing diverse carbazole derivatives, i.e., both electron-rich and electron-deficient systems.
- Przypis, Lukasz,Walczak, Krzysztof Zdzislaw
-
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- Organic metal compounds and organic light emitting diodes comprising the same
-
PURPOSE: An organic metal compound and an organic electroluminescent device containing the same are provided to ensure excellent thermal property and luminescence efficiency, and to be used in a display and a light. CONSTITUTION: An organic metal compound contains a compound of chemical formula 1. An organic electroluminescent device contains the organic metal compound of chemical formula 1. The compound is contained in a light emitting layer between anode and cathode. The organic electroluminescent device comprises one or more layers selected from a hole injection layer, a hole transport layer, an electron blocking layer, a hole blocking layer, an electron transport layer, and an electron injection layer between the anode and the cathode.
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Paragraph 0269; 0270; 0272-0275
(2018/10/19)
-
- Biscarbazole derivative host materials and green emitter for OLED emissive region
-
An organic electroluminescence device utilizes a novel combination comprising one or more biscarbazole derivative compounds as the phosphorescent host material in combination with a green phosphorescent dopant material in the light emitting region of the device, where the biscarbazole derivative compounds are represented by a formula (1A) or (1B) below; where A1 represents a substituted or unsubstituted nitrogen-containing heterocyclic group having 1 to 30 ring carbon atoms; A2 represents a substituted or unsubstituted aromatic hydrocarbon group having 6 to 30 ring carbon atoms, or substituted or unsubstituted nitrogen-containing heterocyclic group having 1 to 30 ring carbon atoms; X1 and X2 each are a linking group; Y1 to Y4 each represent a substituent; p and q represent an integer of 1 to 4; and r and s represent an integer of 1 to 3; and the green phosphorescent dopant material is a phosphorescent organometallic complex having a chemical structure represented by LL′L″M wherein M is a metal that forms octahedral complexes, L, L′, and L″ are equivalent or inequivalent bidentate ligands wherein each L comprises a substituted or unsubstituted phenylpyridine ligand coordinated to M through an sp2 hybridized carbon and N; and, one of L, L′ and L″ is different from at least one of the other two.
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Page/Page column 99-100
(2018/05/24)
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- Organic electroluminescent element and material for organic electroluminescent elements
-
An organic electroluminescence device includes: a cathode; an anode; and an organic thin-film layer having one or more layers and provided between the anode and the cathode, in which the organic layer includes an emitting layer. The emitting layer includes a first host material, a second host material and a phosphorescent dopant material. The first host material is a compound represented by a formula (1A). The second host material is a compound represented by a formula (2A).
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Page/Page column 214
(2017/08/08)
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- Color-tunable thiazole-based iridium(III) complexes: Synthesis, characterization and their OLED applications
-
With respect to the commonly used electron-deficient pyridyl group in the benchmark dopant Ir(ppy)3, incorporating the electron-rich thiazolyl group with different chromophores have not been extensively studied. In this paper, some iridium(III) complexes bearing functional ligands with the thiazolyl moiety were synthesized and characterized by1H and13C NMR, UV–Vis absorption and photoluminescence spectroscopy. The emission color of these thiazole-based Ir(III) complexes can be tuned from yellow to red and the best phosphorescent organic light-emitting device exhibited the maximum external quantum efficiency of 11.1%, current efficiency of 35.8 cd/A and power efficiency of 21.9 lm/W.
- Chau, Nga-Yuen,Ho, Po-Yu,Ho, Cheuk-Lam,Ma, Dongge,Wong, Wai-Yeung
-
-
- An electric element for an organic compound, an organic electronic device and its electric element
-
The present invention provides a novel compound which is capable of improving light-emitting efficiency, stability and lifespan of an element, an organic electronic element using the same, and an electronic device thereof.
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Paragraph 0051; 0052
(2016/10/07)
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- Material for organic electroluminescence device and organic electroluminescence device
-
A material for organic electroluminescence device having a specific central skeleton to which a cyano-substituted aromatic hydrocarbon group or a cyano-substituted heterocyclic group is bonded at its specific position is described. Further described is an organic electroluminescence device including an organic thin film layer between an anode and a cathode. The organic thin film layer include an light emitting layer and at least one layer of the organic thin film layer contains the material for organic electroluminescence device. The material for organic electroluminescence device realizes an organic electroluminescence device with good emission efficiency.
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Page/Page column 135; 136
(2016/05/02)
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- ORGANIC ELECTROLUMINESCENCE ELEMENT, AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT
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An organic electroluminescence device according to an aspect of the invention includes: a cathode; an anode; and an organic thin-film layer disposed between the cathode and the anode, the organic thin-film layer having one or more layers including an emitting layer, in which the emitting layer includes a first material represented by the following formula (1) and a second material in a form of a fluorescent dopant material.
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Page/Page column 82; 83
(2017/03/08)
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- COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF
-
Provided in the present invention are: a novel compound, capable of improving lifespan, stability, and light emitting efficiency of an element; an organic electrical element using the same; and an electronic device thereof. The compound is represented by chemical formula (1).COPYRIGHT KIPO 2016
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Paragraph 0190-0192
(2016/10/17)
-
- Synthesis of Biaryls by Decarboxylative Hiyama Coupling
-
A trimetallic palladium/copper/silver system has been developed that allows the decarboxylative Hiyama coupling of ortho-substituted aryl carboxylates with trialkoxyarylsilanes to give the corresponding biaryls. The cross-coupling is catalyzed by a Pd/N-heterocyclic carbene complex with silver carbonate aiding its reoxidation. Copper(II) fluoride acts as decarboxylation catalyst, stoichiometric oxidant, and fluoride source. The scope of the protocol is demonstrated by 22 examples, among them aryl halides suitable for further coupling, and the synthetic utility of the products is illustrated by their conversion into carbazoles and 1H-indazoles.
- Katayev, Dmitry,Exner, Benjamin,Goossen, Lukas J.
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p. 2028 - 2032
(2015/11/24)
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- Novel organic compounds and an organic electroluminescent device comprising the same
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Provided is an organic compound for a capping layer in an organic electroluminescent device, which is selected from a group comprised of elements represented by chemical formula 1. In addition, provided is an organic electroluminescent device comprising the capping layer (CPL) which is made of the organic compound.COPYRIGHT KIPO 2016
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Paragraph 0088-0091
(2016/10/08)
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- Organic compounds for forming capping layer of an organic electroluminescent device and an organic electroluminescent device comprising the same
-
Provided is an organic compound for forming a capping layer of an organic electroluminescent device selected from a group consisting of chemical formula 1. In addition, provided is the organic electroluminescent device equipped with the capping layer (CPL) made of the organic compound.COPYRIGHT KIPO 2015
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Paragraph 0109-0113
(2016/10/10)
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- COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF
-
The present invention provides a novel compound to improve light emission efficiency and stability of an element and to extend lifespan of the element, an organic electronic element using the same, and an electronic device thereof. The compound is represented by chemical formula 1, wherein m and o are integers in the range of zero and four, and n is an integer in the range of zero and three.(110) Substrate(120) Positive electrode(130) Hole injection layer(140) Hole transfer layer(141) Buffer layer(150) Light emitting layer(151) Light-emitting assisting layer(160) Electron transfer layer(170) Electron injection layer(180) Negative electrodeCOPYRIGHT KIPO 2015
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Paragraph 0136; 0137; 0138; 0139; 0140
(2016/10/08)
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- COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF
-
Provided are a compound of Formula 1 and an organic electric element including a first electrode, a second electrode, and an organic material layer between the first electrode and the second electrode and comprising the compound, the element showing improved luminescence efficiency, stability, and life span.
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Paragraph 0143 - 0145
(2016/10/07)
-
- COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF
-
Disclosed is a compound represented by chemical formula 1. In addition, disclosed is an organic electronic element comprising a first electrode, a second electrode and an organic material layer between the first and second electrodes, wherein the organic material layer includes the compound represented by chemical formula 1. The compound represented by chemical formula 1 is included in the organic material layer, thereby enhancing luminous efficiency, stability and lifespan of the organic electronic element.(110) Substrate(120) Positive electrode(130) Hole injection layer(140) Hole transport layer(141) Buffer layer(150) Light emitting layer(151) Auxiliary light emitting layer(160) Electron transport layer(170) Electron injection layer(180) Negative electrodeCOPYRIGHT KIPO 2015
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Paragraph 0138; 0142-0146
(2016/10/08)
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- COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF
-
Disclosed is a compound presented by chemical formula 1. Disclosed is an organic electronic element including a first electrode, a second electrode, and an organic substance layer located between the first electrode and the second electrode, wherein the organic substance layer includes the compound presented by chemical formula 1. When the compound represented by chemical formula 1, light emitting efficiency, stability, and life of the organic electronic element can be improved.(110) Substrate(120) Positive electrode(130) Hole injection layer(140) Hole transporting layer(141) Buffer layer(150) Light emitting layer(151) Light-emitting assisting layer(160) Electron transporting layer(170) Electron injection layer(180) Negative electrodeCOPYRIGHT KIPO 2015
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Paragraph 0140-0144
(2016/10/08)
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- COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREWITH
-
The present invention provides a novel compound capable of improving light emitting efficiency, stability, and lifespan of the element, an organic element using the same, and an electric device for the same.
- -
-
Paragraph 0089; 0090; 0290
(2015/11/03)
-
- COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF
-
The present invention provides a novel compound capable of improving light emitting efficiency, stability, and lifespan of an element, an organic electronic element using the same, and an electronic device thereof. The organic electronic element comprises a first electrode, a second electrode, and an organic matter layer located between the first electrode and the second electrode, wherein the organic matter layer comprises the compound.(150) Light emitting layer(141) Buffer layer(140) Hole transport layer(130) Hole injection layer(120) Positive electrode(110) Substrate(170) Electron injection layer(160) Electron transport layer(151) Auxiliary light emitting layer(180) Negative electrodeCOPYRIGHT KIPO 2015
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Paragraph 0127-0129
(2016/10/08)
-
- COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF
-
The present invention provides a compound represented by Chemical Formula 1. Moreover, provided is an organic electric element including a first electrode, a second electrode, and an organic material layer between the first electrode and the second electrode, wherein the organic material layer includes the compound represented by Chemical Formula 1. When the compound represented by Chemical Formula 1 is included in the organic material layer of the organic electric element, a driving voltage is reduced, and light emitting efficiency, color purity, and lifecycle may be improved.(110) Substrate(120) Positive electrode(130) Hole injecting layer(140) Hole transporting layer(141) Buffer layer(150) Light-emitting layer(151) Light-emitting assisting layer(160) Electron transferring layer(170) Electron injecting layer(180) Negative electrodeCOPYRIGHT KIPO 2015
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Paragraph 0129-0132; 0151-0154
(2016/10/08)
-
- COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF
-
The present invention provides a novel compound to improve light emission efficiency and stability of an element and to extend lifespan of the element, an organic electronic element using the same, and an electronic device thereof. The compound is represented by chemical formula 1, wherein m is a constant in the range of zero and four, and n is a constant in the range of zero and three.(140) Hole transfer layer(141) Buffer layer(150) Light emitting layer(151) Light-emitting assisting layer(160) Electron transfer layer(170) Electron injection layer(180) Negative electrode(130) Hole injection layer(120) Positive electrode(110) SubstrateCOPYRIGHT KIPO 2015
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Paragraph 0135-0139; 0145; 0146; 0179-0183; 0184; 0185
(2016/10/08)
-
- A NOVEL COMBINATION OF A HOST COMPOUND AND A DOPANT COMPOUND AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME
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The present invention relates to a specific combination of a dopant compound and a host compound, and an organic electroluminescent device comprising the same. The organic electroluminescent device of the present invention provides the advantages of excellent luminous characteristics with lower driving voltages, compared to devices using conventional luminescent materials.
- -
-
Paragraph 172; 173; 174; 175
(2014/01/17)
-
- Carbazole-BODIPY conjugates: Design, synthesis, structure and properties
-
A set of carbazole substituted BODIPYs 2a-2c were designed and synthesized by the Pd-catalysed Sonogashira cross-coupling reaction. The effects of variation in the donor strength of various carbazoles were investigated by photophysical, electrochemical and computational studies. The electronic absorption spectra of BODIPYs 2a and 2c show charge transfer bands, which show red shift in polar solvents. The BODIPYs 2a-2c are highly fluorescent in nonpolar solvents (emission from the localized state) and poorly fluorescent in polar solvents (emission from the charge transfer state). The photophysical and electrochemical studies reveal strong donor-acceptor interaction between carbazole and BODIPY and follows the order 2a > 2c > 2b. The computational calculations show good agreement with the experimental results. The single crystal structures of BODIPYs 2a-2c are reported, which exhibit interesting supramolecular interactions. The packing diagrams of 2a show a zigzag 3D structural arrangement, whereas 2b and 2c show complex 3D structural motifs. This journal is the Partner Organisations 2014.
- Misra, Rajneesh,Jadhav, Thaksen,Dhokale, Bhausaheb,Gautam, Prabhat,Sharma, Rekha,Maragani, Ramesh,Mobin, Shaikh M.
-
p. 13076 - 13086
(2014/08/18)
-
- Optimizing the photovoltaic performance of thiocyanate-free ruthenium photosensitizers by structural modification of C^N cyclometalating ligand in dye-sensitized solar cells
-
Five new thiocyanate-free ruthenium(II) complexes with different electron-donating functionalized cyclometalating ligands C^N were synthesized, characterized and applied as photosensitizers in dye-sensitized solar cells (DSSCs). Their photophysical, electrochemical, thermal and photovoltaic properties have been investigated and density functional theory (DFT) calculations have been carried out on these dyes. These dyes exhibit good thermal stability with the onset decomposition temperature at 5% weight-loss (Td) of around 330 °C. The DSSC device using the Ru(II) dye with the 9-tolylcarbazole chromophore exhibited the highest power conversion efficiency (η) up to 3.39%, with a short-circuit photocurrent density (Jsc) of 8.06 mA cm-2, an open-circuit photovoltage (Voc) of 0.62 V and a high fill factor (ff) of 0.68 under illumination of an AM 1.5 solar cell simulator.
- Siu, Chi-Ho,Ho, Cheuk-Lam,He, Jian,Chen, Tao,Majumda, Poulomi,Zhao, Jianzhang,Li, Hua,Wong, Wai-Yeung
-
-
- NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME
-
The present invention relates to a novel organic electroluminescent compound and an organic electroluminescent device comprising the same. The organic electroluminescent compound according to the present invention is better in luminous efficiency and lifespan characteristics compared to conventional materials. Using the compounds of the present invention, it is possible to manufacture an OLED device with a long operational lifespan. In addition, the compounds can improve the power efficiency of the device to reduce overall power consumption.
- -
-
Paragraph 196-198
(2013/08/28)
-
- Synthesis of nitrodienes, nitrostyrenes, and nitrobiaryls through palladium-catalyzed couplings of β-nitrovinyl and o-nitroaryl thioethers
-
A highly efficient, base-free, mild protocol for the palladium-catalyzed, copper-activated desulfitative couplings of vinyl and aryl β- nitrothioethers generates a wide variety of conjugated nitroorganics. Orthogonality to traditional Suzuki-Miyaura coupling is demonstrated, as well as synthetic utility, through reductive Cadogan cyclization, for the formation of indoles, carbazoles, and pyrroles.
- Creech, Gardner S.,Kwon, Ohyun
-
p. 2670 - 2674
(2013/07/11)
-
- BIS-CARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME
-
A biscarbazole derivative of the invention is represented by a formula (1A or (1B) below. In the formula (1A) or (1B): A1 represents a substituted or unsubstituted nitrogen-containing heterocyclic group having 1 to 30 ring carbon atoms; A2 represents a substituted or unsubstituted aromatic hydrocarbon group having 6 to 30 ring carbon atoms, or substituted or unsubstituted nitrogen-containing heterocyclic group having 1 to 30 ring carbon atoms; X1 and X2 each are a linking group; Y1 to Y4 each represent a substituent; p and q represent an integer of 1 to 4; and r and s represent an integer of 1 to 3.
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Page/Page column 114-115
(2012/02/15)
-
- Carbazole-based coplanar molecule (CmInF) as a universal host for multi-color electrophosphorescent devices
-
The synthesis, isomerism, photophysics and electrophosphorescent characterization of some functional cyclometallated iridium(iii) complexes containing 2-[2-(N-phenylcarbazolyl)]pyridine and 2-[3-(N-phenylcarbazolyl)] pyridine molecular frameworks are described. A carbazole-based coplanar molecule (CmInF) obtained through the intramolecular ring closure of aryl substitutions at the C3 and C6 positions exhibits a high triplet energy (ET = 2.77 eV), morphological stability (Tg = 195 °C) and hole mobility in the range of up to 5 × 10-3 cm2 V-1 s-1. Highly efficient multi-color electrophosphorescent devices have been successfully achieved employing CmInF as the universal host material doped with phosphorescent dopants of various colors under the same device configuration of ITO/PEDOT:PSS (300 A)/TCTA (250 A)/CmInF: dopant (250 A)/TAZ (500 A)/LiF/Al (PEDOT:PSS = poly(ethylene dioxythiophene):polystyrene sulfonate; TCTA = 4,4′,4′′-tri(N- carbazolyl)triphenylamine; TAZ = 3-(4-biphenylyl)-4-phenyl-5-(4-tert- butylphenyl)-1,2,4-triazole). Through the mixing of two phosphorescent dopants of complementary colors, we also fabricated a two-color white organic light-emitting device (WOLED) with the same device structure consisting of 12 wt% FIrpic and 0.3 wt% (Mpg)2Ir(acac) co-doped into CmInF as a single-emitting-layer, which exhibits peak WOLED efficiency of 13.4% (23.4 cd A-1) and 11.2 lm W-1 with the Commission Internationale de L'Eclairage (CIE) coordinates of (0.33, 0.37). In addition, the use of such device structure in full-color OLEDs has the advantages of simplifying manufacturing process and reducing production cost that are the critical issues of commercialization.
- Ho, Cheuk-Lam,Chi, Liang-Chen,Hung, Wen-Yi,Chen, Wei-Jiun,Lin, Yu-Cheng,Wu, Hao,Mondal, Ejabul,Zhou, Gui-Jiang,Wong, Ken-Tsung,Wong, Wai-Yeung
-
experimental part
p. 215 - 224
(2012/07/01)
-
- Asymmetric anthracene-based blue host materials: Synthesis and electroluminescence properties of 9-(2-naphthyl)-10-arylanthracenes
-
A series of bulky aryl-substituted asymmetric anthracene blue host materials, 9-(2-naphthyl)-10-(3-(1-naphthyl)phenyl)anthracene, where phenyl was varied from H (5a), Me (5b), Ph (5e), and 1-Naph (5f) at the 6-position and Me (5c) at the 2-position, was s
- Wee, Kyung-Ryang,Han, Won-Sik,Kim, Ju-Eun,Kim, Ae-Li,Kwon, Soonnam,Kang, Sang Ook
-
experimental part
p. 1115 - 1123
(2011/09/16)
-
- Carbazole-linked porphyrin dimers for organic light emitting diodes: Synthesis and initial photophysical studies
-
Carbazole linked porphyrin dimers were synthesized in good yields via stepwise Suzuki coupling reactions using bromoporphyrins and borylated carbazoles as the precursors, the latter of which were synthesized via known procedures from biphenyl derivatives. For comparative purposes porphyrin-carbazole monomers were synthesized. Single layer organic light emitting diodes (OLEDs) were created to demonstrate the optical properties of these materials. Light emission from these carbazole substituted porphyrins showed better results compared to previously examined bromo substituted porphyrins with better electroluminescence and lower turn-on voltages. Dimers exhibited turn-on voltages of 3 V compared to 6 V for monomeric porphyrin-carbazoles.
- Ryan, Aoife,Tuffy, Brian,Horn, Sabine,Blau, Werner J.,Senge, Mathias O.
-
scheme or table
p. 8248 - 8254
(2011/11/12)
-
- Synthesis of functionalized ellipticinium and ellipticine derivatives via electrophilic cyclization
-
An efficient methodology for the synthesis of highly functionalized ellipticinium and ellipticine derivatives starting from the corresponding 2-bromocarbazoles via an AgOTf or CuI catalyzed electrophilic cyclization of 2-alkynyl-3-carbazolylaldimines is reported.
- Chaitanya, T. Krishna,Nagarajan, Rajagopal
-
scheme or table
p. 4662 - 4670
(2011/07/08)
-
- Air stable electron-transporting and ambipolar bay substituted perylene bisimides
-
Four new perylene bisimides containing carbazolyl and triphenylamino electron-donor groups in the bay region have been designed, synthesized and characterized. The materials possess high thermal stability and form uniform films. They display a wide absorption window extending to the near infrared region of the spectrum and demonstrate efficient photoinduced intramolecular electron transfer. Ionization potential values of these perylene bisimide derivatives measured by photoelectron spectroscopy range from 5.8 eV to 6 eV. Charge-transporting properties were investigated by the xerographic time of flight (XTOF) technique. Complementary ambipolar charge-transport was observed in differently linked carbazolyl substituted perylene bisimides while the triphenylamino substituted material exhibited competent electron drift mobility (>10-3 cm2 V-1 cm-1) under ambient conditions. Density functional theory (DFT) calculations were performed for carbazolyl bay substituted perylene bisimides in order to understand the complementary ambipolar charge transport as well as the difference in the optical properties.
- Reghu, Renji R.,Bisoyi, Hari Krishna,Grazulevicius, Juozas V.,Anjukandi, Padmesh,Gaidelis, Valentas,Jankauskas, Vygintas
-
scheme or table
p. 7811 - 7819
(2011/12/22)
-
- Practical syntheses of N-hexylcarbazol-2-yl- and -3-yl-boronic acids, their cross-coupled products and a derived tris-cyclometalated (pyridin-2-yl) carbazole iridium(III) complex
-
The syntheses of N-hexylcarbazol-2-yl- and -3-yl-boronic acids (1 and 2) are described on a ca. 7 g scale, starting from commercially available 2,5-dibromonitrobenzene (4) and carbazole (11), respectively. Compounds 1 and 2 underwent efficient palladium-catalyzed cross-coupling reactions under Suzuki-Miyaura conditions to yield products 17,18 and 20. Compound 18 reacted with IrCl3 to give the tris-cyclometalated (pyridin-2-yl)carbazole iridium(III) complex 21, the X-ray crystal structure of which is reported. Georg Thieme Verlag Stuttgart.
- Tavasli, Mustafa,Bettington, Sylvia,Bryce, Martin R.,Batsanov, Andrei S.,Monkman, Andrew P.
-
p. 1619 - 1624
(2007/10/03)
-
- Cardioselective antiischemic ATP-sensitive potassium channel openers. 4. Structure-activity studies on benzopyranylcyanoguanidines: Replacement of the benzopyran portion
-
The results of our efforts aimed at the replacement of the benzopyran ring of the lead cardiac selective antiischemic ATP-sensitive potassium channel (K(ATP)) opener (4) are described. Systematic modification of the benzopyran ring of 4 resulted in the discovery of a structurally simpler acyclic analog (8) with slightly lower antiischemic potency than the lead compound 4. Further structure-activity studies on the acyclic analog 8 provided the 2- phenoxy-3-pyridylurea analog 18 with improved antiischemic potency and selectivity compared to the benzopyran-based compound 4. These data demonstrate that the benzopyran ring of 4 and its congeners is not mandatory for antiischemic activity and cardiac selectivity. The results described in this paper also show that, as for the benzopyran class of compounds, the structure-activity relationships for the antiischemic and vasorelaxant activities of K(ATP) openers are distinct. The mechanism of action of the acyclic analogs (e.g., 18) still appears to involve K(ATP) opening as their cardioprotective effects are abolished by pretreatment with the K(ATP) blocker glyburide.
- Atwal, Karnail S.,Ferrara, Francis N.,Ding, Charles Z.,Grover, Gary J.,Sleph, Paul G.,Dzwonczyk, Steven,Baird, Anne J.,Normandin, Diane E.
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p. 304 - 313
(2007/10/03)
-
- Aryl urea and related compounds
-
Compounds having the formula STR1 and pharmaceutically acceptable salts thereof wherein X is a single bond, O, CO, S, NH or N(lower alkyl); Y is O, S or NCN; and R 1 to R 5'' are as defined herein. These compounds have potassium channel activating activit
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- A NEW METHOD OF SYNTHESIS OF α-ARYLPROPIONIC ACIDS INVOLVING COPPER(I) HOMOGENEOUS CATALYSIS
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The synthesis of α-arylpropionic acids involving, as first step, the facile coupling af an aryl bromide and diethyl malonate in the presence of Cu(I) bromide is described.The limits of application are discussed.
- Ugo, Renato,Nardi, Paola,Psaro, Rinaldo,Roberto, Dominique
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p. 511 - 514
(2007/10/02)
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