70873-41-5

Basic information

• Product Name: 4'-Bromo-2-nitro-biphenyl
• Synonyms: 4'-Bromo-2-nitro-biphenyl;4-bromo-2-nitro-1,1'-biphenyl
• CAS NO: 70873-41-5
• Molecular Formula: C₁₂H₈BrNO₂
• Molecular Weight: 278.10142
• Mol File: 70873-41-5.mol
• Article Data: 40

Chemical Properties

• Melting Point: 59-60 °C(Solv: ligroine (8032-32-4))
• Boiling Point: 361.8°C at 760 mmHg
• Flash Point: 172.6°C
• Appearance: /
• Density: 1.521g/cm³
• Vapor Pressure: 4.21E-05mmHg at 25°C
• Refractive Index: 1.63
• CAS DataBase Reference: 4'-Bromo-2-nitro-biphenyl(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-Bromo-2-nitro-biphenyl(70873-41-5)
• EPA Substance Registry System: 4'-Bromo-2-nitro-biphenyl(70873-41-5)

Safety Data

• Hazardous Substances Data: 70873-41-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H8BrNO2/c13-10-6-7-11(12(8-10)14(15)16)9-4-2-1-3-5-9/h1-8H

Upstream product

• 3460-18-2 1,4-dibromo-2-nitrobenzene 
• 98-80-6 phenylboronic acid 
• 2996-92-1 phenyl trimethylsiloxane 
• 92-66-0 4-bromo-1,1'-biphenyl 
• 112671-42-8 4-bromo-1-iodo-2-nitrobenzene 
• 881-50-5 N-(4-bromo-2-nitrophenyl)acetamide 
• 71-43-2 benzene 
• 875-51-4 4-Bromo-2-nitroaniline 

Downstream Products

• 1313526-55-4 9-ethyl-6-methyl-2-(2-phenylethynyl)-9H-carbazole-3-carbaldehyde 
• 1313526-69-0 2-(4-chlorophenyl)-6-ethyl-9-methyl-3-phenyl-6H-pyrido[4,3-b]carbazol-2-ium triflate 
• 1313526-71-4 6-ethyl-9-methyl-3-phenyl-2-p-tolyl-6H-pyrido[4,3-b]carbazol-2-ium triflate 
• 1313526-73-6 6-ethyl-9-methyl-2-pentyl-3-phenyl-6H-pyrido[4,3-b]carbazol-2-ium triflate 
• 1313526-75-8 2-allyl-6-ethyl-9-methyl-3-phenyl-6H-pyrido[4,3-b]carbazol-2-ium triflate 
• 1313526-95-2 9-ethyl-2-(2-phenylethynyl)-9H-carbazolw-3-carbaldehyde 
• 1313526-77-0 6-ethyl-7,9-dimethyl-3-phenyl-2-p-tolyl-6H-pyrido[4,3-b]carbazol-2-ium triflate 
• 1313526-79-2 6-ethyl-2-(4-methoxyphenyl)-7,9-dimethyl-3-phenyl-6H-pyrido[4,3-b]carbazol-2-ium triflate 
• 1313526-81-6 6-ethyl-2-(furan-2-ylmethyl)-7,9-dimethyl-3-phenyl-6H-pyrido[4,3-b]carbazol-2-ium triflate 
• 1313526-83-8 2-(4-chlorophenyl)-6-ethyl-7,9-dimethyl-3-phenyl-6H-pyrido[4,3-b]carbazol-2-ium triflate 
• 1313526-85-0 2-allyl-6-ethyl-7,9-dimethyl-3-phenyl-6H-pyrido[4,3-b]carbazol-2-ium triflate 
• 1313526-96-3 9-ethyl-6,8-dimethyl-2-(phenylethynyl)-9H-carbazole-3-carbaldehyde 
• 1313526-56-5 6-ethyl-9-methyl-3-phenyl-6H-pyrido[4,3-b]carbazole 
• 1313526-98-5 6-ethyl-3-phenyl-6H-pyrido[4,3-b]carbazole 

Relevant articles and documents

LIPOXYGENASE INHIBITORS

Various embodiments of the present disclosure are directed to compounds having Formula I, Formula II, Formula IIA, Formula III, Formula IIIA, Formula IIIB, and/or pharmaceutically acceptable salts thereof. The compounds can be suitable for inhibiting lipoxygenases and/or treating associated diseases. In some embodiments, subject compounds are used to prepare a composition that is effective in treating neurodegenerative diseases.

PHENYL-SULFAMOYL.BENZOYC ACIDS AS ERAP1 MODULATORS

The present invention relates to a compound of formula (I), or a pharmaceutically acceptable salt or hydrate thereof, wherein: the group X-Y is -NHSO2- or -SO2NH-; Z is a monocyclic aryl or heteroaryl group, each of which is optionally substituted by one ormore substituents selected from alkyl, cycloalkyl, halo, alkoxy, CN, haloalkyl and OH; R1 is H or alkyl; R2 is selected from COOH and a tetrazolyl group; R3 is selected from H, C land alkyl; R4 is selected from H and halo; R5 is selected from H, alkyl, haloalkyl, SO2-alkyl,Cl, alkoxy, OH, CN, hydroxyalkyl, alkylthio, heteroaryl, cycloalkyl, heterocycloalkyl andhaloalkoxy; R6 is H; R7 is selected from H, CN, haloalkyl, halo, SO2-alkyl,SO2NR12R13, heteroaryl, CONR10R11 and alkyl, wherein said heteroaryl group is optionallysubstituted by one or more substituents selected from alkyl, halo, alkoxy, CN, haloalkyl and OH; R8 is selected from H, alkyl, haloalkyl and halo; and R9 is H, alkyl or halo; R10 and R11 are each independently H or alkyl; and R12 and R13 are each independently H or alkyl. Further aspects of the invention relate to such compounds for use in the field of immuno- oncology and related applications. Another aspect of the invention relates to compounds of formulae (la) and (lb).

Copper(II)-Catalyzed Iodinations of Carbazoles: Access to Functionalized Carbazoles

A copper-catalyzed iodination of carbazoles has been developed. Barluenga's reagent IPy2BF4 is used to generate a soft electrophilic halonium species for the iodination of the carbazoles. This report represents the first concept of copper-catalyst-promoted electrophilic halogenation of carbazoles. We demonstrated numerous applications of this methodology synthesizing diverse carbazole derivatives, i.e., both electron-rich and electron-deficient systems.