70873-41-5

Usage

InChI:InChI=1/C12H8BrNO2/c13-10-6-7-11(12(8-10)14(15)16)9-4-2-1-3-5-9/h1-8H

Upstream product

• 875-51-4 4-Bromo-2-nitroaniline 
• 71-43-2 benzene 
• 3460-18-2 1,4-dibromo-2-nitrobenzene 
• 98-80-6 phenylboronic acid 
• 2996-92-1 phenyl trimethylsiloxane 
• 112671-42-8 4-bromo-1-iodo-2-nitrobenzene 
• 881-50-5 N-(4-bromo-2-nitrophenyl)acetamide 
• 92-66-0 4-bromo-1,1'-biphenyl 

Downstream Products

• 41604-22-2 4-bromo-2-amino-1,1'-biphenyl 
• 1313526-55-4 9-ethyl-6-methyl-2-(2-phenylethynyl)-9H-carbazole-3-carbaldehyde 
• 1313526-69-0 2-(4-chlorophenyl)-6-ethyl-9-methyl-3-phenyl-6H-pyrido[4,3-b]carbazol-2-ium triflate 
• 1313526-71-4 6-ethyl-9-methyl-3-phenyl-2-p-tolyl-6H-pyrido[4,3-b]carbazol-2-ium triflate 
• 1313526-73-6 6-ethyl-9-methyl-2-pentyl-3-phenyl-6H-pyrido[4,3-b]carbazol-2-ium triflate 
• 1313526-75-8 2-allyl-6-ethyl-9-methyl-3-phenyl-6H-pyrido[4,3-b]carbazol-2-ium triflate 
• 1313526-95-2 9-ethyl-2-(2-phenylethynyl)-9H-carbazolw-3-carbaldehyde 
• 1313526-77-0 6-ethyl-7,9-dimethyl-3-phenyl-2-p-tolyl-6H-pyrido[4,3-b]carbazol-2-ium triflate 
• 1313526-79-2 6-ethyl-2-(4-methoxyphenyl)-7,9-dimethyl-3-phenyl-6H-pyrido[4,3-b]carbazol-2-ium triflate 
• 1313526-81-6 6-ethyl-2-(furan-2-ylmethyl)-7,9-dimethyl-3-phenyl-6H-pyrido[4,3-b]carbazol-2-ium triflate 
• 1313526-83-8 2-(4-chlorophenyl)-6-ethyl-7,9-dimethyl-3-phenyl-6H-pyrido[4,3-b]carbazol-2-ium triflate 
• 1313526-85-0 2-allyl-6-ethyl-7,9-dimethyl-3-phenyl-6H-pyrido[4,3-b]carbazol-2-ium triflate 
• 1313526-96-3 9-ethyl-6,8-dimethyl-2-(phenylethynyl)-9H-carbazole-3-carbaldehyde 
• 1313526-56-5 6-ethyl-9-methyl-3-phenyl-6H-pyrido[4,3-b]carbazole 

Relevant academic research and scientific papers

LIPOXYGENASE INHIBITORS

Various embodiments of the present disclosure are directed to compounds having Formula I, Formula II, Formula IIA, Formula III, Formula IIIA, Formula IIIB, and/or pharmaceutically acceptable salts thereof. The compounds can be suitable for inhibiting lipoxygenases and/or treating associated diseases. In some embodiments, subject compounds are used to prepare a composition that is effective in treating neurodegenerative diseases.

LIPOXYGENASE INHIBITORS

Various embodiments of the present disclosure are directed to compounds having Formula (I), Formula (IA), Formula (IB), Formula (IC), Formula (ID), Formula (IE), and/or pharmaceutically acceptable salts thereof. The compounds can be suitable for inhibiting lipoxygenases, and/or treating associated diseases, such as Alzheimer's disease. In some embodiments, the compounds may be administered to a patient as part of a pharmaceutical formulation.

PHENYL-SULFAMOYL.BENZOYC ACIDS AS ERAP1 MODULATORS

The present invention relates to a compound of formula (I), or a pharmaceutically acceptable salt or hydrate thereof, wherein: the group X-Y is -NHSO2- or -SO2NH-; Z is a monocyclic aryl or heteroaryl group, each of which is optionally substituted by one ormore substituents selected from alkyl, cycloalkyl, halo, alkoxy, CN, haloalkyl and OH; R1 is H or alkyl; R2 is selected from COOH and a tetrazolyl group; R3 is selected from H, C land alkyl; R4 is selected from H and halo; R5 is selected from H, alkyl, haloalkyl, SO2-alkyl,Cl, alkoxy, OH, CN, hydroxyalkyl, alkylthio, heteroaryl, cycloalkyl, heterocycloalkyl andhaloalkoxy; R6 is H; R7 is selected from H, CN, haloalkyl, halo, SO2-alkyl,SO2NR12R13, heteroaryl, CONR10R11 and alkyl, wherein said heteroaryl group is optionallysubstituted by one or more substituents selected from alkyl, halo, alkoxy, CN, haloalkyl and OH; R8 is selected from H, alkyl, haloalkyl and halo; and R9 is H, alkyl or halo; R10 and R11 are each independently H or alkyl; and R12 and R13 are each independently H or alkyl. Further aspects of the invention relate to such compounds for use in the field of immuno- oncology and related applications. Another aspect of the invention relates to compounds of formulae (la) and (lb).

A compound. Hole transporting material, organic electroluminescent device and display device (by machine translation)

The invention provides a compound of general formula (I). It can be used for hole transport materials. The compound has the fluorene fused ring-linked ortho-substituted phenyl triarylamine parent structure, the bond between atoms can be high, good thermal stability is achieved, solid deposition between molecules is facilitated, and the transition capability of holes is high. Be applied to hole transport layer, have suitable energy level level between adjacent level, be favorable to the injection and the migration of hole, can effectively reduce drive voltage, higher hole mobility simultaneously, can effectively promote organic electroluminescence device's luminous efficiency. The invention also provides a hole transport material comprising the compound of the general formula (I). Organic electroluminescent device and display device. (by machine translation)

Copper(II)-Catalyzed Iodinations of Carbazoles: Access to Functionalized Carbazoles

A copper-catalyzed iodination of carbazoles has been developed. Barluenga's reagent IPy2BF4 is used to generate a soft electrophilic halonium species for the iodination of the carbazoles. This report represents the first concept of copper-catalyst-promoted electrophilic halogenation of carbazoles. We demonstrated numerous applications of this methodology synthesizing diverse carbazole derivatives, i.e., both electron-rich and electron-deficient systems.

Organic metal compounds and organic light emitting diodes comprising the same

PURPOSE: An organic metal compound and an organic electroluminescent device containing the same are provided to ensure excellent thermal property and luminescence efficiency, and to be used in a display and a light. CONSTITUTION: An organic metal compound contains a compound of chemical formula 1. An organic electroluminescent device contains the organic metal compound of chemical formula 1. The compound is contained in a light emitting layer between anode and cathode. The organic electroluminescent device comprises one or more layers selected from a hole injection layer, a hole transport layer, an electron blocking layer, a hole blocking layer, an electron transport layer, and an electron injection layer between the anode and the cathode.

Biscarbazole derivative host materials and green emitter for OLED emissive region

An organic electroluminescence device utilizes a novel combination comprising one or more biscarbazole derivative compounds as the phosphorescent host material in combination with a green phosphorescent dopant material in the light emitting region of the device, where the biscarbazole derivative compounds are represented by a formula (1A) or (1B) below; where A1 represents a substituted or unsubstituted nitrogen-containing heterocyclic group having 1 to 30 ring carbon atoms; A2 represents a substituted or unsubstituted aromatic hydrocarbon group having 6 to 30 ring carbon atoms, or substituted or unsubstituted nitrogen-containing heterocyclic group having 1 to 30 ring carbon atoms; X1 and X2 each are a linking group; Y1 to Y4 each represent a substituent; p and q represent an integer of 1 to 4; and r and s represent an integer of 1 to 3; and the green phosphorescent dopant material is a phosphorescent organometallic complex having a chemical structure represented by LL′L″M wherein M is a metal that forms octahedral complexes, L, L′, and L″ are equivalent or inequivalent bidentate ligands wherein each L comprises a substituted or unsubstituted phenylpyridine ligand coordinated to M through an sp2 hybridized carbon and N; and, one of L, L′ and L″ is different from at least one of the other two.

Organic electroluminescent element and material for organic electroluminescent elements

An organic electroluminescence device includes: a cathode; an anode; and an organic thin-film layer having one or more layers and provided between the anode and the cathode, in which the organic layer includes an emitting layer. The emitting layer includes a first host material, a second host material and a phosphorescent dopant material. The first host material is a compound represented by a formula (1A). The second host material is a compound represented by a formula (2A).

Color-tunable thiazole-based iridium(III) complexes: Synthesis, characterization and their OLED applications

With respect to the commonly used electron-deficient pyridyl group in the benchmark dopant Ir(ppy)3, incorporating the electron-rich thiazolyl group with different chromophores have not been extensively studied. In this paper, some iridium(III) complexes bearing functional ligands with the thiazolyl moiety were synthesized and characterized by1H and13C NMR, UV–Vis absorption and photoluminescence spectroscopy. The emission color of these thiazole-based Ir(III) complexes can be tuned from yellow to red and the best phosphorescent organic light-emitting device exhibited the maximum external quantum efficiency of 11.1%, current efficiency of 35.8 cd/A and power efficiency of 21.9 lm/W.

An electric element for an organic compound, an organic electronic device and its electric element

The present invention provides a novel compound which is capable of improving light-emitting efficiency, stability and lifespan of an element, an organic electronic element using the same, and an electronic device thereof.