A one-pot synthesis of functionalized ethyl 1,3-thiazole-5-carboxylates from thioamides or thioureas and 2-chloro-1,3-dicarbonyl compounds in an ionic liquid
A simple one-pot synthesis of functionalized ethyl 1,3-thiazole-5- carboxylates from the reaction of 2-chloro-1,3-dicarbonyl compounds with thioureas or thioamides in the presence of 1-butyl-3-methylimidazolium trifluoromethanesulfonate is described. Grap
Yavari, Issa,Sayyed-Alangi, S. Zahra,Hajinasiri, Rahimeh,Sajjadi-Ghotbabadi, Hadi
experimental part
p. 209 - 211
(2010/03/26)
THIAZOLE COMPOUNDS
The present invention provides compounds of formula (I) wherein all variables are as defined herein, pharmaceutical compositions containing the same, processes for preparing the same and their use as pharmaceutical agents.
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Page/Page column 76
(2008/06/13)
Heterocyclic Analogues of the Antihypertensive β-Adrenergic Blocking Agent (S)-2--3-cyanopyridine
The syntheses of a series of isoelectronic analogues of (S)-2--3-cyanopyridine (1) are described; included in this group are examples of thiazole, isothiazole, thiadiazole, pyrazine, and the structurally related napht
Baldwin, John J.,Engerhardt, Edward L.,Hirshmann, Ralph,Ponticello, Gerald S.,Atkinson, Joseph G.,et al
p. 65 - 70
(2007/10/02)
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