726138-31-4

Basic information

• Product Name: 2-Amino-3,5-diphenylpyridine
• Synonyms: 2-Amino-3,5-diphenylpyridine
• CAS NO: 726138-31-4
• Molecular Formula: C₁₇H₁₄N₂
• Molecular Weight: 246.31
• Mol File: 726138-31-4.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Amino-3,5-diphenylpyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-3,5-diphenylpyridine(726138-31-4)
• EPA Substance Registry System: 2-Amino-3,5-diphenylpyridine(726138-31-4)

Safety Data

• Hazardous Substances Data: 726138-31-4(Hazardous Substances Data)

Usage

Applications

Used in organic chemistry as a building block for:
Synthesis of pharmaceuticals
Synthesis of agrochemicals
Synthesis of dyes
Studied for potential pharmacological properties including:
Anti-cancer effects
Anti-inflammatory effects

Biological Activities

Investigated for potential pharmacological properties
Potential anti-cancer and anti-inflammatory effects

Industrial Applications

Valuable intermediate in organic synthesis
Utilized in various industries

Upstream product

• 35486-42-1 2-amino-3,5-dibromopyridine 
• 98-80-6 phenylboronic acid 
• 13965-03-2 bis-triphenylphosphine-palladium(II) chloride 
• 497-19-8 sodium carbonate 
• 504-29-0 2-aminopyridine 

Downstream Products

• 726138-30-3 2-(4-bromo-phenyl)-6,8-diphenyl-imidazo[1,2-a]pyridine 
• 873913-89-4 [3-(3,5-diphenyl-pyridin-2-yl)-prop-2-ynyl]-dimethyl-amine 
• 873913-82-7 2-iodo-3,5-diphenylpyridine 

Relevant articles and documents

Synthesis and evaluation of the anticoccidial activity of trifluoropyrido[1,2-a]pyrimidin-2-one derivatives

Screening of our chemical library to discover new molecules exhibiting in vitro activity against the invasion of host cells by Eimeria tenella revealed a lead compound with an IC50 of 15 μM. Structure-activity relationship studies were conducted with 34 newly synthesized compounds to identify more active molecules and enhance in vitro activity against the parasite. Four compounds were more effective in inhibiting MDBK cell invasion in vitro than the lead compound.

Pyrene derivatives comprising heteroaryl amine group and organic light-emitting diode including the same

The present invention relates to a pyrene derivative represented by chemical formula A, and an organic light-emitting diode including the same. In the chemical formula A, substituents Z, Ar_1, Ar_2, R_1 to R_5, connecting groups L_1 and L_2, and X, m, p and q are the same as defined in a detailed description of the present invention.COPYRIGHT KIPO 2015

AMIDE COMPOUND

The present invention relate to a compound represented by the formula (I) or (II) wherein ring A is an optionally substituted ring (the ring should not be pyrrolidine, piperidine and piperazine), ring B is an optionally substituted aromatic ring, ring D is an optionally substituted ring, R1 and R2 are each independently a hydrogen atom or a substituent, R3 is a hydrogen atom or a C1-6 alkyl group, or R3 is bonded to ring A to form a non-aromatic ring, ring Aa is an optionally substituted aromatic hydrocarbon, Y is CH or N, Ra1 is an optionally substituted hydrocarbon group, and Ra2 and Ra3 are each independently a hydrogen atom or a substituent, or a salt thereof. The present invention provides a compound having a DGAT inhibitory activity, which is useful for the treatment or amelioration of diseases or pathologies caused by high expression or high activation of DGAT.

AMIDE COMPOUND

Disclosed is a compound represented by the formula (I) or (II) below, or a salt thereof. [In the formulae, ring A represents an optionally substituted ring (which is not a pyrrolidine, piperidine or piperazine); ring B represents an optionally substituted aromatic ring; ring D represents an optionally substituted ring; R1 and R2 independently represent a hydrogen atom or a substituent; R3 represents a hydrogen atom or a C1-6 alkyl group, or alternatively it combines with the ring A to form a non-aromatic ring; ring Aa represents an optionally substituted aromatic hydrocarbon; Y represents CH or N; Ra1 represents an optionally substituted hydrocarbon group; and Ra2 and Ra3 independently represent a hydrogen atom or a substituent.] The compound has a DGAT inhibitory effect and is useful for treatment or improvement of diseases or conditions caused by high expression or high activation of DGAT.

New calcineurin inhibiting 3-dimethylaminopropyl substituted diarylheterocycles by sonogashira reactions and catalytic hydrogenation

A series of calcineurin inhibiting compounds 1 consisting of a central aromatic N-heterocycle, two aryl substituents and a 3-dimethylaminopropyl chain was synthesized by introduction of the side chain. A corresponding haloheterocycle 3 was transformed int

NITROGENOUS HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME

A specific derivative of heterocyclic compound having nitrogen atom and an organic electroluminescence device comprising the compound. An organic electroluminescence device comprising at least one of organic compound layers including a light emitting layer sandwiched between an anode and a cathode, wherein said at least one of the organic compound layers comprises the derivative of the heterocyclic compound having nitrogen atom as a sole component or as mixed component. The organic electroluminescence device achieves elevation of luminance and excellent efficiency of light emission, and also achieves long lifetime by an improvement of an electrode adhesion.