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72916-31-5

ethyl 6-amino-4-(2-chlorophenyl)-5-cyano-2-phenyl-4H-pyran-3-carboxylate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 72916-31-5 Structure

  • Basic information

    1. Product Name: ethyl 6-amino-4-(2-chlorophenyl)-5-cyano-2-phenyl-4H-pyran-3-carboxylate
    2. Synonyms: 4H-Pyran-3-carboxylic acid, 6-amino-4-(2-chlorophenyl)-5-cyano-2-phenyl-, ethyl ester; Ethyl 6-amino-4-(2-chlorophenyl)-5-cyano-2-phenyl-4H-pyran-3-carboxylate
    3. CAS NO:72916-31-5
    4. Molecular Formula: C21H17ClN2O3
    5. Molecular Weight: 380.8243
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 72916-31-5.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 595.3°C at 760 mmHg
    3. Flash Point: 313.8°C
    4. Appearance: N/A
    5. Density: 1.34g/cm3
    6. Vapor Pressure: 3.89E-14mmHg at 25°C
    7. Refractive Index: 1.641
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: ethyl 6-amino-4-(2-chlorophenyl)-5-cyano-2-phenyl-4H-pyran-3-carboxylate(CAS DataBase Reference)
    11. NIST Chemistry Reference: ethyl 6-amino-4-(2-chlorophenyl)-5-cyano-2-phenyl-4H-pyran-3-carboxylate(72916-31-5)
    12. EPA Substance Registry System: ethyl 6-amino-4-(2-chlorophenyl)-5-cyano-2-phenyl-4H-pyran-3-carboxylate(72916-31-5)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 72916-31-5(Hazardous Substances Data)

72916-31-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 72916-31-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,9,1 and 6 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 72916-31:
(7*7)+(6*2)+(5*9)+(4*1)+(3*6)+(2*3)+(1*1)=135
135 % 10 = 5
So 72916-31-5 is a valid CAS Registry Number.

72916-31-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl 6-amino-4-(2-chlorophenyl)-5-cyano-2-phenyl-4H-pyran-3-carboxylate

1.2 Other means of identification

Product number -
Other names HMS618I16

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:72916-31-5 SDS

72916-31-5Downstream Products

72916-31-5Relevant articles and documents

New tacrine-derived AChE/BuChE inhibitors: Synthesis and biological evaluation of 5-amino-2-phenyl-4H-pyrano[2,3-b]quinoline-3-carboxylates

Eghtedari, Mohammad,Sarrafi, Yaghoub,Nadri, Hamid,Mahdavi, Mohammad,Moradi, Alireza,Homayouni Moghadam, Farshad,Emami, Saeed,Firoozpour, Loghman,Asadipour, Ali,Sabzevari, Omid,Foroumadi, Alireza

, p. 237 - 246 (2017/02/15)

A series of poly-functionalized tacrine-derived compounds namely 5-amino-2-phenyl-4H-pyrano[2,3-b]quinoline-3-carboxylates were designed and synthesized as cholinesterases inhibitors. The in?vitro inhibition assay against AChE and BuChE demonstrated that most of compounds had potent AChE inhibitory with reserving potential of BuChE inhibition. Among them, compound 6i bearing a 4-(3-bromophenyl) moiety showed the most potent activity against AChE/BuChE (IC50s values of 0.069 and 1.35?μM, respectively). The anti-AChE activity of 6i was five times more than that of tacrine. The SAR study revealed that chloro/bromo substituent at ortho or meta position of the 4-phenyl ring can improve the anticholinesterase activity.

Dibutylamine-catalysed efficient one-pot synthesis of biologically potent pyrans

Kalla, Reddi Mohan Naidu,Kim, Mi Ri,Kim, Il

supporting information, p. 717 - 720 (2015/01/30)

An expedient, eco-friendly and efficient procedure for the preparation of novel pyran derivatives has been developed through a solvent-free, one-pot reaction of various aldehydes, malononitrile and either methylacetoacetate or ethyl benzoylacetate in the presence of dibutylamine (2.5 mol %) at room temperature. This procedure is advantageous because it is mild, environmentally friendly, gives high yields and requires short reaction times. Furthermore, the product did not necessitate separation via extraction and column chromatography.

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